4.8 Article

The effects of glycols on molecular mobility, structure, and permeability in stratum corneum

Related references

Note: Only part of the references are listed.
Article Biophysics

The effect of pH and salt on the molecular structure and dynamics of the skin

Enamul Haque Mojumdar et al.

Summary: The study investigates how variations in pH, ionic strength, and salt composition influence the structure and dynamics of the stratum corneum (SC) lipid and protein components. The highest molecular mobility in both lipid and protein components is observed at the lowest pH of 4.0. The study results provide new insights on how SC molecular properties respond to solution conditions, which can be beneficial in developing topical drug delivery and cosmetic formulations.

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

Article Pharmacology & Pharmacy

In Vitro-In Vivo Correlation in Dermal Delivery: The Role of Excipients

Avnish Patel et al.

Summary: The composition of topical and transdermal formulations plays a crucial role in determining the drug delivery rate and extent through the skin. This study investigated the effects of commonly used excipients on the percutaneous absorption of ibuprofen, finding PG, DPG, and TPG to be more effective than PEG 300 in drug delivery. Quantitative CRS showed a positive correlation with in vitro diffusion studies, indicating its potential as a powerful tool for evaluating drug and vehicle delivery from dermal formulations.

PHARMACEUTICS (2021)

Article Chemistry, Physical

Extraction of natural moisturizing factor from the stratum corneum and its implication on skin molecular mobility

Maria Gunnarsson et al.

Summary: The study investigates the impact of NMF on skin molecular dynamics and the reversal of its effects by adding specific NMF components. It was found that removing NMF reduces molecular mobility in the skin, but replacing it with single NMF components restores molecular dynamics.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2021)

Article Dermatology

Effect of propylene glycol on the skin penetration of drugs

Victor Carrer et al.

ARCHIVES OF DERMATOLOGICAL RESEARCH (2020)

Article Chemistry, Medicinal

QbD-Based Investigation of Dermal Semisolid in situ Film-Forming Systems for Local Anaesthesia

Anita Kovacs et al.

DRUG DESIGN DEVELOPMENT AND THERAPY (2020)

Review Chemistry, Multidisciplinary

Recent strategies in spray drying for the enhanced bioavailability of poorly water-soluble drugs

Mark Davis et al.

JOURNAL OF CONTROLLED RELEASE (2018)

Article Chemistry, Analytical

Following-up skin penetration of lidocaine from different vehicles by Raman spectroscopic mapping

Monika Bakonyi et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2018)

Article Multidisciplinary Sciences

Tracking solvents in the skin through atomically resolved measurements of molecular mobility in intact stratum corneum

Quoc Dat Pham et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Skin hydration: interplay between molecular dynamics, structure and water uptake in the stratum corneum

Enamul Haque Mojumdar et al.

SCIENTIFIC REPORTS (2017)

Article Chemistry, Multidisciplinary

Chemical penetration enhancers in stratum corneum - Relation between molecular effects and barrier function

Quoc Dat Pham et al.

JOURNAL OF CONTROLLED RELEASE (2016)

Review Pharmacology & Pharmacy

Permeation enhancer strategies in transdermal drug delivery

Harneet Marwah et al.

DRUG DELIVERY (2016)

Article Chemistry, Physical

Stratum corneum molecular mobility in the presence of natural moisturizers

Sebastian Bjorklund et al.

SOFT MATTER (2014)

Review Pharmacology & Pharmacy

Novel chemical permeation enhancers for transdermal drug delivery

Yang Chen et al.

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2014)

Article Biochemical Research Methods

Signal intensities in 1H-13C CP and INEPT MAS NMR of liquid crystals

A. Nowacka et al.

JOURNAL OF MAGNETIC RESONANCE (2013)

Article Multidisciplinary Sciences

Characterization of Stratum Corneum Molecular Dynamics by Natural-Abundance 13C Solid-State NMR

Sebastian Bjorklund et al.

PLOS ONE (2013)

Review Chemistry, Multidisciplinary

Approaches for breaking the barriers of drug permeation through transdermal drug delivery

Amit Alexander et al.

JOURNAL OF CONTROLLED RELEASE (2012)

Article Pharmacology & Pharmacy

Chemical Penetration Enhancers for Transdermal Drug Delivery Systems

IB Pathan et al.

TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH (2011)

Article Chemistry, Multidisciplinary

Polarization Transfer Solid-State NMR for Studying Surfactant Phase Behavior

Agnieszka Nowacka et al.

LANGMUIR (2010)

Review Chemistry, Physical

Diffusional transport in responding lipid membranes

Emma Sparr et al.

SOFT MATTER (2009)

Article Pharmacology & Pharmacy

Alteration of Skin Hydration and its Barrier Function by Vehicle and Permeation Enhancers: A Study using TGA, FTIR, TEWL and Drug Permeation as Markers

D. K. Shah et al.

METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY (2008)

Article Biochemistry & Molecular Biology

Stratum corneum hydration: Phase transformations and mobility in stratum corneum, extracted lipids and isolated corneocytes

C. L. Silva et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2007)

Article Biochemical Research Methods

matNMR:: A flexible toolbox for processing, analyzing and visualizing magnetic resonance data in Matlab®

Jacco D. van Beek

JOURNAL OF MAGNETIC RESONANCE (2007)

Review Biochemistry & Molecular Biology

The skin barrier in healthy and diseased state

Joke A. Bouwstra et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2006)

Review Pharmacology & Pharmacy

Dermal and transdermal drug delivery systems: Current and future prospects

MB Brown et al.

DRUG DELIVERY (2006)

Review Chemistry, Multidisciplinary

Activity of water in aqueous systems; A frequently neglected property

MJ Blandamer et al.

CHEMICAL SOCIETY REVIEWS (2005)

Review Pharmacology & Pharmacy

Penetration enhancers

AC Williams et al.

ADVANCED DRUG DELIVERY REVIEWS (2004)