4.5 Article

Integrated age-related immunohistological changes occur in human olfactory epithelium and olfactory bulb

Related references

Note: Only part of the references are listed.
Article Otorhinolaryngology

Heterogeneous distribution of mature olfactory sensory neurons in human olfactory epithelium

Kazuhiro Omura et al.

Summary: The study revealed that the distribution and differentiation degree of mature olfactory sensory neurons are heterogeneous throughout the olfactory epithelium. Resection of the anterior or superior superior turbinate potentially damages olfactory function, while resection of the inferior or posterior superior turbinate or widening of the superior meatus is a safer alternative that does not damage mature olfactory sensory neurons or alter airflow to the olfactory cleft.

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY (2022)

Article Medicine, Research & Experimental

Aging-related olfactory loss is associated with olfactory stem cell transcriptional alterations in humans

Allison D. Oliva et al.

Summary: This study identified inflammation-associated changes in the olfactory epithelium (OE) stem cells of presbyosmic patients, suggesting that these changes may contribute to olfactory loss by disrupting normal epithelial homeostasis. The findings suggest that OE stem cells could be a therapeutic target for restoring olfaction.

JOURNAL OF CLINICAL INVESTIGATION (2022)

Article Otorhinolaryngology

Evaluation of the Neuroanatomical Basis of Olfactory Dysfunction in the General Population

Ran Lu et al.

Summary: This study revealed that olfactory bulb volume was independently correlated with odor identification function and mediated the age-related association between volumes of central olfactory structures and olfactory function.

JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY (2021)

Review Cell Biology

Initiation of the age-related decline of odor identification in humans: A meta-analysis

Chenping Zhang et al.

AGEING RESEARCH REVIEWS (2017)

Article Environmental Sciences

Fine particulate matter exposure and olfactory dysfunction among urban dwelling older US adults

Gaurav S. Ajmani et al.

ENVIRONMENTAL RESEARCH (2016)

Article Otorhinolaryngology

Office-based olfactory mucosa biopsies

Eric H. Holbrook et al.

INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY (2016)

Review Geriatrics & Gerontology

Olfaction and Aging: A Mini-Review

Johannes Attems et al.

GERONTOLOGY (2015)

Article Neurosciences

Injury in aged animals robustly activates quiescent olfactory neural stem cells

Jessica H. Brann et al.

FRONTIERS IN NEUROSCIENCE (2015)

Review Neurosciences

Aging in the olfactory system

Arie S. Mobley et al.

TRENDS IN NEUROSCIENCES (2014)

Review Psychology, Multidisciplinary

The influences of age on olfaction: a review

Richard L. Doty et al.

FRONTIERS IN PSYCHOLOGY (2014)

Article Medicine, Research & Experimental

Immunohistochemical Characterization of Human Olfactory Tissue

Eric H. Holbrook et al.

LARYNGOSCOPE (2011)

Article Multidisciplinary Sciences

Age-induced disruption of selective olfactory bulb synaptic circuits

Marion B. Richard et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Clinical Neurology

Biopsies of Olfactory Epithelium in Patients with Parkinson's Disease

Martin Witt et al.

MOVEMENT DISORDERS (2009)

Article Neurosciences

Correlation between olfactory bulb volume and olfactory function

D. Buschueter et al.

NEUROIMAGE (2008)

Article Medicine, Research & Experimental

Abnormalities of axon growth in human olfactory mucosa

EH Holbrook et al.

LARYNGOSCOPE (2005)