Noncanonical Sensing Mechanisms for Bacillus subtilis Chemoreceptors

Bodhankar et al. reported a noncanonical sensing mechanism that involves signal interaction with the McpA chemoreceptor signaling domain resulting in a chemorepellence response of Bacillus subtilis. The identified repellent binding site is analogous to that for attractant binding in McpB, another B. subtilis chemoreceptor.

Automated summary

Bodhankar et al. discovered a novel sensing mechanism in which the signal interacts with the McpA chemoreceptor signaling domain, resulting in a chemorepellence response in Bacillus subtilis. The identified binding site for the repellent is analogous to the attractant binding site in McpB, another chemoreceptor in B. subtilis.