Strepolyketide D, a new SEK15-derived polyketide compound from salt-lake-derived Streptomyces sp. DBC5

Article Plant Sciences

Chemical constituents from salt lake-derived Streptomyces sp. QHA10

Hao-Wen Zhao et al.

Summary: In this study, two new alkaloids and one new enoic acid were successfully isolated from the liquid fermentation of Streptomyces sp. QHA10 derived from a salt lake. The structures of these compounds were determined through extensive spectroscopic data analysis and X-ray diffraction. One of the new compounds exhibited potential anti-inflammatory activity by inhibiting nitric oxide production.

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2021)

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Article Plant Sciences

Strepyrazinone, a tricyclic diketopiperazine derivative with cytotoxicity from a marine-derived actinobacterium

Lu Zhang et al.

Summary: Strepyrazinone (1), a novel tricyclic diketopiperazine derivative with an unprecedented carbon skeleton in natural products, was isolated from marine-derived Streptomyces sp. B223. Its cytotoxic activity against HCT-116 cancer cell lines with an IC(50) value of 0.34 μM was demonstrated.

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2021)

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Review Biochemical Research Methods

Polyketide pesticides from actinomycetes

Shanshan Li et al.

Summary: Natural product derived polyketide pesticides have gained popularity worldwide due to their high efficacy, eco-friendly nature, and safety profile, with advancements in the development of such pesticides from actinomycetes in recent decades. These pesticides, such as avermectins, spinosyns, polynactins, tetramycin, and their analogues, have shown successful applications in crop protection, with continuous improvement driven by biotechnological advances.

CURRENT OPINION IN BIOTECHNOLOGY (2021)

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Article Chemistry, Medicinal