Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 25, Issue 2, Pages 197-204Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2022.2076673
Keywords
Streptomyces sp; polyketide; antioxidant activity; strepolyketide D
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A new polyketide compound was isolated from salt-lake-derived Streptomyces sp. DBC5 and showed moderate antioxidation.
A new SEK15-derived polyketide compound, strepolyketide D (1), was isolated from salt-lake-derived Streptomyces sp. DBC5, together with two known analogues (2-3). Their structures were elucidated based on spectroscopic analysis of IR, MS, 1 D and 2 D NMR. Compound 2 elicited moderate antioxidation with IC50 value of 39.26 mu g/ml. The results of the study revealed that salt-lake actinomycetes of Lake Dabancheng appear to have immense potential as a source of polyketide compounds.
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