Journal
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
Volume 24, Issue 6, Pages 503-517Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10286020.2022.2064284
Keywords
Cruciferae; Isatis indigotica; sulfonated alkaloid; isatithiomidosulfonate A; isatindosulfonic acids; isatithienopysulfonic acids
Funding
- National Natural Sciences Foundation of China [81630094, 81730093]
- CAMS Innovation Fund for Medical Science [2021-I2M-1-028]
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In this study, eleven new sulfonated alkaloids with diverse structures were isolated from an aqueous extract of Isatis indigotica root. The structures were determined using spectroscopic data analysis, chemical methods, and theoretical calculations, with (-)-4 being confirmed by single crystal X-ray diffraction.
Eleven new sulfonated alkaloids (1 - 11) having diverse structures were isolated from an aqueous extract of the Isatis indigotica root (ban lan gen). Their structures were determined by spectroscopic data analysis, chemical method, and theoretical calculation, of which (-)-4 was proved by single crystal X-ray diffraction.
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