4.6 Article

Preparation of multifunctional biohydrogel sensors with one freeze-thaw process

Journal

JOURNAL OF APPLIED POLYMER SCIENCE
Volume 139, Issue 27, Pages -

Publisher

WILEY
DOI: 10.1002/app.52482

Keywords

biocompatibility; biopolymers and renewable polymers; composites

Funding

  1. Natural Science Basic Research Plan in Shaanxi Province of China [2021JQ-541]
  2. National Natural Science Foundation of China [52003146, 52103008]
  3. Young Talent Fund of University Association for Science and Technology in Shaanxi, China [20210407]

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A biosensor based on hydrogels with good biocompatibility, antifreezing, and moisturizing properties was successfully synthesized in this study. The sensor could maintain conductivity under extreme conditions, and has potential bio-applications.
Conductive hydrogels have a significant prospect in the design of bioactuators, healthcare monitoring sensors, and flexible wearable devices. However, their poor temperature tolerance and biotoxicity limit their further applications. In this study, a biosensor based on hydrogels with good biocompatibility, antifreezing, and moisturizing properties was synthesized using a one freeze-thaw process. The sensor could withstand 60 degrees C for 400 min or -20 degrees C without freezing and maintain good conductivity. The excellent antibacterial activity and biocompatibility of the sensor ensure the safety of its biosecurity applications. Thus, the proposed biosensor has potential bio-applications as a bionic material under extreme conditions.

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