Journal
INTERNATIONAL JOURNAL OF NANOMEDICINE
Volume 17, Issue -, Pages 2097-2119Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/IJN.S361282
Keywords
diabetic wound healing; nanoparticles; antibacterial; low cytotoxicity; good biocompatibility; drug delivery
Funding
- National Natural Science Foundation of China [31961133015, 21736002, 31870791]
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Developing dressings that can accelerate the healing of diabetic wounds is of great clinical significance. Nanoparticles have significant advantages in promoting wound healing due to their antibacterial properties, low cytotoxicity, good biocompatibility, and drug delivery ability. Adding nanoparticles to dressings and using them to deliver drugs and cytokines has been proven to be effective.
Chronic wound caused by diabetes is an important cause of disability and seriously affects the quality of life of patients. Therefore, it is of great clinical significance to develop a wound dressing that can accelerate the healing of diabetic wounds. Nanoparticles have great advantages in promoting diabetic wound healing due to their antibacterial properties, low cytotoxicity, good biocompatibility and drug delivery ability. Adding nanoparticles to the dressing matrix and using nanoparticles to deliver drugs and cytokines to promote wound healing has proven to be effective. This review will focus on the effects of diabetes on wound healing, introduce the properties, preparation methods and action mechanism of nanoparticles in wound healing, and describe the effects and application status of various nanoparticle-loaded dressings in diabetes-related chronic wound healing.
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