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The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response
Anna Mandinova et al.
EMBO JOURNAL (2008)
The two-faced NF-kappa B in the skin
Inderpreet Sur et al.
INTERNATIONAL REVIEWS OF IMMUNOLOGY (2008)
Notch signaling: Its role in epidermal homeostasis and in the pathogenesis of skin diseases
Ryuhei Okuyama et al.
JOURNAL OF DERMATOLOGICAL SCIENCE (2008)
EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer
Vihren Kolev et al.
NATURE CELL BIOLOGY (2008)
Properties of the six isoforms of p63:: p53-like regulation in response to genotoxic stress and cross talk with ΔNp73
A. Petitjean et al.
CARCINOGENESIS (2008)
Molecular basis of the Li-Fraumeni syndrome:: an update from the French LFS families
G. Bougeard et al.
JOURNAL OF MEDICAL GENETICS (2008)
P53 and the pathogenesis of skin cancer
Cara L. Benjamin et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
Transcription regulation by mutant p53
L. Weisz et al.
ONCOGENE (2007)
Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKα kinases
Karine Lefort et al.
GENES & DEVELOPMENT (2007)
Srcasm corrects Fyn-induced epidermal hyperplasia by kinase down-regulation
Weijie Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Dimethyl sulfoxide to vorinostat: Development of this histone deacetylase inhibitor as an anticancer drug
Paul A. Marks et al.
NATURE BIOTECHNOLOGY (2007)
Dasatinib: a new step in molecular target therapy
A. Olivieri et al.
ANNALS OF ONCOLOGY (2007)
Identification of differentially expressed genes in cutaneous squamous cell carcinoma by microarray expression profiling
Ingo Nindl et al.
MOLECULAR CANCER (2006)
Impaired Notch signaling promotes de novo squamous cell carcinoma formation
Aaron Proweller et al.
CANCER RESEARCH (2006)
Real-time PCR analysis of a 3895 bp mitochondrial DNA deletion in nonmelanoma skin cancer and its use as a quantitative marker for sunlight exposure in human skin
A. Harbottle et al.
BRITISH JOURNAL OF CANCER (2006)
Genome-wide transcriptional profiling in human squamous cell carcinoma of the skin identifies unique tumor-associated signatures
Vinnie P. Kathpalia et al.
JOURNAL OF DERMATOLOGY (2006)
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation
BC Nguyen et al.
GENES & DEVELOPMENT (2006)
The incidence of both tandem duplications and the common deletion in mtDNA from three distinct categories of sun-exposed human skin and in prolonged culture of fibroblasts
Kim J. Krishnan et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2006)
Nucleotide excision repair and cancer
Diana Leibeling et al.
JOURNAL OF MOLECULAR HISTOLOGY (2006)
Divorcing ARF and p53: an unsettled case
Charles J. Sherr
NATURE REVIEWS CANCER (2006)
The Ras superfamily at a glance
K Wennerberg et al.
JOURNAL OF CELL SCIENCE (2005)
Srcasm modulates EGF and Src-kinase signaling in keratinocytes
WJ Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
CDK4 regulation by TNFR1 and JNK is required for NF-κB-mediated epidermal growth control
JY Zhang et al.
JOURNAL OF CELL BIOLOGY (2005)
INK4-ARF and p53 mutations in metastatic cutaneous squamous cell carcinoma - Case report and archival study on the use of Ink4a-ARF and p53 mutation analysis in identification of the corresponding primary tumor
WAM Blokx et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2005)
High commitment of embryonic keratinocytes to terminal differentiation through a notch1-caspase 3 regulatory mechanism
R Okuyama et al.
DEVELOPMENTAL CELL (2004)
A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors
MF Fraga et al.
CANCER RESEARCH (2004)
P16INK4a and p14ARF tumor suppressor genes are commonly inactivated in cutaneous squamous cell carcinoma
VL Brown et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2004)
E-cadherin promoter hypermethylation in preneoplastic and neoplastic skin lesions
MC Chiles et al.
MODERN PATHOLOGY (2003)
Biomarkers of human cutaneous squamous cell carcinoma from tissues and cell lines identified by DNA microarrays and qRT-PCR
TP Dooley et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
The ΔNp63α phosphoprotein binds the p21 and 14-3-3σ promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
MD Westfall et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Mutational analysis of CDKN2A genes in patients with squamous cell carcinoma of the skin
Z Saridaki et al.
BRITISH JOURNAL OF DERMATOLOGY (2003)
Notch1 functions as a tumor suppressor in mouse skin
M Nicolas et al.
NATURE GENETICS (2003)
TP53 mutations in human skin cancers
G Giglia-Mari et al.
HUMAN MUTATION (2003)
Progression of actinic keratosis to squamous cell carcinoma of the skin correlates with deletion of the 9p21 region encoding the p16INK4a tumor suppressor
L Mortier et al.
CANCER LETTERS (2002)
Srcasm: a novel Src activating and signaling molecule
JT Seykora et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The INK4a/ARF network in tumour suppression
CJ Sherr
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
p63α and ΔNp63α can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes
M Dohn et al.
ONCOGENE (2001)
CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-κB
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The spectrum of mitochondrial DNA deletions is a ubiquitous marker of ultraviolet radiation exposure in human skin
AJ Ray et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2000)