Related references
Note: Only part of the references are listed.Mechanisms Leading to Differential Hypoxia-Inducible Factor Signaling in the Diabetic Kidney: Modulation by SGLT2 Inhibitors and Hypoxia Mimetics
Milton Packer
AMERICAN JOURNAL OF KIDNEY DISEASES (2021)
The journey from erythropoietin to 2019 Nobel Prize: Focus on hypoxia-inducible factors in the kidney
Szu-Yu Pan et al.
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION (2021)
Hypoxia-inducible factors not only regulate but also are myeloid-cell treatment targets
Lovis Kling et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2021)
The crosstalk between HIFs and mitochondrial dysfunctions in cancer development
Xingting Bao et al.
CELL DEATH & DISEASE (2021)
Interleukin-6 blockade, a potential adjunct therapy for post-burn hypermetabolism
Dalia Barayan et al.
FASEB JOURNAL (2021)
Targeting MCL-1 in cancer: current status and perspectives
Haolan Wang et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2021)
The Role of Mitochondria in Acute Kidney Injury and Chronic Kidney Disease and Its Therapeutic Potential
Xiaoqin Zhang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Photocleavable proteins that undergo fast and efficient dissociation
Xiaocen Lu et al.
CHEMICAL SCIENCE (2021)
Cardiovascular Disease, Aging, and Clonal Hematopoiesis
Megan A. Evans et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 15, 2020 (2020)
The role of hypoxia-inducible factors in neovascular age-related macular degeneration: a gene therapy perspective
Parviz Mammadzada et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2020)
Bcl-XL: A multifunctional anti-apoptotic protein
Mingxue Li et al.
PHARMACOLOGICAL RESEARCH (2020)
Roles of Nrf2 in Protecting the Kidney from Oxidative Damage
Masahiro Nezu et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference
Marlies Ostermann et al.
KIDNEY INTERNATIONAL (2020)
Melatonin Antagonizes Nickel-Induced Aerobic Glycolysis by Blocking ROS-Mediated HIF-1α/miR210/ISCU Axis Activation
Mindi He et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2020)
If it's not one thing, HIF's another: immunoregulation by hypoxia inducible factors in disease
Ffion R. Hammond et al.
FEBS JOURNAL (2020)
Diabetic atherosclerosis: is there a role for the hypoxia-inducible factors?
Daniela Pirri et al.
BIOSCIENCE REPORTS (2020)
Hypoxia-inducible factor-1: A potential pharmacological target to manage psoriasis
Wen-Jing Zhu et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2020)
Hypoxia-inducible factors and innate immunity in liver cancer
Vincent Wai-Hin Yuen et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Hypoxia-inducible factors and diabetes
Jenny E. Gunton
JOURNAL OF CLINICAL INVESTIGATION (2020)
HIF-1α as a Mediator of Insulin Resistance, T2DM, and Its Complications: Potential Links With Obstructive Sleep Apnea
Agata Gabryelska et al.
FRONTIERS IN PHYSIOLOGY (2020)
The Importance of Hypoxia-Inducible Factors (HIF-1 and HIF-2) for the Pathophysiology of Inflammatory Bowel Disease
Evelyn L. Kerber et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
An intimate crosstalk between iron homeostasis and oxygen metabolism regulated by the hypoxia-inducible factors (HIFs)
Kiichi Hirota
FREE RADICAL BIOLOGY AND MEDICINE (2019)
Acute Kidney Injury After Burn: A Cohort Study From the Parkland Burn Intensive Care Unit
Audra T. Clark et al.
JOURNAL OF BURN CARE & RESEARCH (2019)
Acute kidney injury in trauma patients admitted to the ICU: a systematic review and meta-analysis
Signe Sovik et al.
INTENSIVE CARE MEDICINE (2019)
Hypoxia and Hypoxia-Inducible Factors in Kidney Injury and Repair
Shaoqun Shu et al.
CELLS (2019)
Predictive Biomarkers for Acute Kidney Injury in Burn Patients
Amir Emami et al.
JOURNAL OF BURN CARE & RESEARCH (2019)
Influences of Hypoxia Exercise on Whole-Body Insulin Sensitivity and Oxidative Metabolism in Older Individuals
Kristine Chobanyan-Juergens et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2019)
Management of Burns
David G. Greenhalgh
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Initial management of severe burn injury
Shawn Tejiram et al.
CURRENT OPINION IN CRITICAL CARE (2019)
Relationship Between Intermittent Hypoxia and Type 2 Diabetes in Sleep Apnea Syndrome
Hiroyo Ota et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Mechanisms of hypoxia signalling: new implications for nephrology
Johannes Schoedel et al.
NATURE REVIEWS NEPHROLOGY (2019)
Hypoxia-Inducible Factors as an Alternative Source of Treatment Strategy for Cancer
Musbau Adewumi Akanji et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
Mcl-1 and Bcl-xL are essential for survival of the developing nervous system
Lauren C. Fogarty et al.
CELL DEATH AND DIFFERENTIATION (2019)
HIF-1α/BNIP3 signaling pathway-induced-autophagy plays protective role during myocardial ischemia-reperfusion injury
Yanan Zhang et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
MITOCHONDRIAL FUNCTION IN THE KIDNEY AND HEART, BUT NOT THE BRAIN, IS MAINLY ALTERED IN AN EXPERIMENTAL MODEL OF ENDOTOXAEMIA
Marina Makrecka-Kuka et al.
SHOCK (2019)
Hypoxia-Induced ROS Contribute to Myoblast Pyroptosis during Obstructive Sleep Apnea via the NF-κB/HIF-1α Signaling Pathway
Li-Ming Yu et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
HIF-1α protects against oxidative stress by directly targeting mitochondria
Hong-Sheng Li et al.
REDOX BIOLOGY (2019)
Bax, Bak and beyond - mitochondrial performance in apoptosis
Aida Pena-Blanco et al.
FEBS JOURNAL (2018)
The Role of Succinate in Regulation of Immediate HIF-1α Expression in Hypoxia
L. D. Lukyanova et al.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2018)
Cardiorespiratory Fitness and Cardiovascular Disease Prevention: an Update
Mouaz H. Al-Mallah et al.
CURRENT ATHEROSCLEROSIS REPORTS (2018)
Hypoxia-inducible transcription factors, HIF1A and HIF2A, increase in aging mucosal tissues
Jeffrey L. Ebersole et al.
IMMUNOLOGY (2018)
Cancer stem cells and hypoxia-inducible factors (Review)
Wei-Wei Tong et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2018)
The role of hypoxia-inducible factors in leukemias
Donata Szymczak et al.
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE (2018)
Effects of Resveratrol on the Renin-Angiotensin System in the Aging Kidney
In-Ae Jang et al.
NUTRIENTS (2018)
The BCL-2 arbiters of apoptosis and their growing role as cancer targets
Jerry M. Adams et al.
CELL DEATH AND DIFFERENTIATION (2018)
Renal Aging: Causes and Consequences
Eoin D. O'Sullivan et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)
Genetics of the hypoxia-inducible factors in human cancers
Keiji Tanimoto
EXPERIMENTAL CELL RESEARCH (2017)
Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1α and Repression of NF-κB
Jonathan Braverman et al.
JOURNAL OF IMMUNOLOGY (2017)
Understanding nucleosome dynamics and their links to gene expression and DNA replication
William K. M. Lai et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins
Abdel Aouacheria et al.
NEUROCHEMISTRY INTERNATIONAL (2017)
Caspase-9: structure, mechanisms and clinical application
Ping Li et al.
ONCOTARGET (2017)
Hypoxia inducible factors in hepatocellular carcinoma
Chu Chen et al.
ONCOTARGET (2017)
Maintenance of redox homeostasis by hypoxia-inducible factors
Debangshu Samanta et al.
REDOX BIOLOGY (2017)
The biochemical alterations underlying post-burn hypermetabolism
Christopher Auger et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
Hypoxia augments LPS-induced inflammation and triggers high altitude cerebral edema in mice
Yanzhao Zhou et al.
BRAIN BEHAVIOR AND IMMUNITY (2017)
The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus
Philipp A. Gerber et al.
ANTIOXIDANTS & REDOX SIGNALING (2017)
Hypoxia-inducible factors as neuroprotective agent in Alzheimer's disease
Ben Sundra Ashok et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2017)
HIF-1 at the crossroads of hypoxia, inflammation, and cancer
Kuppusamy Balamurugan
INTERNATIONAL JOURNAL OF CANCER (2016)
A detailed evaluation of the new acute kidney injury criteria by KDIGO in critically ill patients
Junichi Izawa et al.
JOURNAL OF ANESTHESIA (2016)
Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer
Johannes Schoedel et al.
EUROPEAN UROLOGY (2016)
Postburn Hypermetabolism: Past, Present, and Future
Marc G. Jeschke
JOURNAL OF BURN CARE & RESEARCH (2016)
Role of ROS and RNS Sources in Physiological and Pathological Conditions
Sergio Di Meo et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer
Caroline Wigerup et al.
PHARMACOLOGY & THERAPEUTICS (2016)
The Role of BCL-2 Family Members In Acute Kidney Injury
Steven C. Borkan
SEMINARS IN NEPHROLOGY (2016)
Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study
Eric A. J. Hoste et al.
INTENSIVE CARE MEDICINE (2015)
Regulation of Hypoxia-Inducible Factor-1a by Reactive Oxygen Species : New Developments in an Old Debate
Shahrzad Movafagh et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2015)
The definition of acute kidney injury and its use in practice
Mark E. Thomas et al.
KIDNEY INTERNATIONAL (2015)
Structural integration in hypoxia-inducible factors
Dalei Wu et al.
NATURE (2015)
The Role of Oxygen Sensors, Hydroxylases, and HIF in Cardiac Function and Disease
W. H. Davin Townley-Tilson et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)
RENAL AUTOREGULATION IN HEALTH AND DISEASE
Mattias Carlstrom et al.
PHYSIOLOGICAL REVIEWS (2015)
Structural Mechanism for Regulation of Bcl-2 protein Noxa by phosphorylation
Christine B. Karim et al.
SCIENTIFIC REPORTS (2015)
Phosphorylation of the BNIP3 C-Terminus Inhibits Mitochondrial Damage and Cell Death without Blocking Autophagy
Katherine E. Liu et al.
PLOS ONE (2015)
Time-Dependent and Organ-Specific Changes in Mitochondrial Function, Mitochondrial DNA Integrity, Oxidative Stress and Mononuclear Cell Infiltration in a Mouse Model of Burn Injury
Bartosz Szczesny et al.
PLOS ONE (2015)
Molecular mechanisms of ischemic preconditioning in the kidney
Pinelopi P. Kapitsinou et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2015)
Transcriptional regulation by hypoxia inducible factors
Veronica L. Dengler et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2014)
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
Peter E. Czabotar et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Role of Hypoxia-Inducible Factors in Acute Kidney Injury
Kelly K. Andringa et al.
NEPHRON CLINICAL PRACTICE (2014)
Enhanceosomes as integrators of hypoxia inducible factor (HIF) and other transcription factors in the hypoxic transcriptional response
Matthew R. Pawlus et al.
CELLULAR SIGNALLING (2013)
Acute kidney injury after cardiac surgery according to Risk/Injury/Failure/Loss/End-stage, Acute Kidney Injury Network, and Kidney Disease: Improving Global Outcomes classifications
Anthony J. Bastin et al.
JOURNAL OF CRITICAL CARE (2013)
Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen
Andrew L. Doedens et al.
NATURE IMMUNOLOGY (2013)
Regulation of hypoxia-inducible factor-1α (HIF-1α) expression by interleukin-1β (IL-1β), insulin-like growth factors I (IGF-I) and II (IGF-II) in human osteoarthritic chondrocytes
Angelica Rossi Sartori-Cintra et al.
CLINICS (2012)
The Acute Kidney Injury Network (AKIN) Criteria Applied in Burns
Kevin K. Chung et al.
JOURNAL OF BURN CARE & RESEARCH (2012)
The HIF1 target gene NOX2 promotes angiogenesis through urotensin-II
Isabel Diebold et al.
JOURNAL OF CELL SCIENCE (2012)
Cooperativity of Stress-Responsive Transcription Factors in Core Hypoxia-Inducible Factor Binding Regions
Diego Villar et al.
PLOS ONE (2012)
Myeloid cell leukemia-1 (Mc1-1) is a candidate target gene of hypoxia-inducible factor-1 (HIF-1) in the testis
Michael A. Palladino et al.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2012)
Vascular Heterogeneity in the Kidney
Grietje Molema et al.
SEMINARS IN NEPHROLOGY (2012)
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
Gregg L. Semenza
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Overexpression of Pyruvate Dehydrogenase Kinase 3 Increases Drug Resistance and Early Recurrence in Colon Cancer
Chun-Wun Lu et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
Johannes Schoedel et al.
BLOOD (2011)
Hypoxia-Inducible Factor 1 Mediates Increased Expression of NADPH Oxidase-2 in Response to Intermittent Hypoxia
Guoxiang Yuan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2011)
Determinants and dynamics of genome accessibility
Oliver Bell et al.
NATURE REVIEWS GENETICS (2011)
Long-Term Persistance of the Pathophysiologic Response to Severe Burn Injury
Marc G. Jeschke et al.
PLOS ONE (2011)
Hypoxia-inducible factors and the prevention of acute organ injury
Samuel N. Heyman et al.
CRITICAL CARE (2011)
Acute kidney injury in critically ill burn patients. Risk factors, progression and impact on mortality
Tina Palmieri et al.
BURNS (2010)
Outcome of acute kidney injury in severe burns: a systematic review and meta-analysis
Nele Brusselaers et al.
INTENSIVE CARE MEDICINE (2010)
Factor inhibiting HIF limits the expression of hypoxia-inducible genes in podocytes and distal tubular cells
Johannes Schoedel et al.
KIDNEY INTERNATIONAL (2010)
The NADPH Oxidase Subunit NOX4 Is a New Target Gene of the Hypoxia-inducible Factor-1
Isabel Diebold et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
The BCL-2 Family Reunion
Jerry E. Chipuk et al.
MOLECULAR CELL (2010)
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
Amar J. Majmundar et al.
MOLECULAR CELL (2010)
HIF-1 and HIF-2 transcription factors - Similar but not identical
Agnieszka Loboda et al.
MOLECULES AND CELLS (2010)
Mitochondria and cell death: outer membrane permeabilization and beyond
Stephen W. G. Tait et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
HIF-Prolyl Hydroxylases in the Rat Kidney Physiologic Expression Patterns and Regulation in Acute Kidney Injury
Johannes Schoedel et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Iron-Based Redox Switches in Biology
F. Wayne Outten et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
J. Zhang et al.
CELL DEATH AND DIFFERENTIATION (2009)
Mitochondrial targeting of tBid/Bax: a role for the TOM complex?
M. Ott et al.
CELL DEATH AND DIFFERENTIATION (2009)
MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2
Stephen Y. Chan et al.
CELL METABOLISM (2009)
Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation
Erich B. Tahara et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
BCL-xL Is a Target Gene Regulated by Hypoxia-inducible Factor-1α
Ni Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
David R. Mole et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Abnormal Insulin Sensitivity Persists up to Three Years in Pediatric Patients Post-Burn
Gerd G. Gauglitz et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia
Yair Benita et al.
NUCLEIC ACIDS RESEARCH (2009)
Preferential binding of HIF-1 to transcriptionally active loci determines cell-type specific response to hypoxia
Xiaobo Xia et al.
GENOME BIOLOGY (2009)
Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax
Jonathan F. Lovell et al.
CELL (2008)
Biology of HIF-1 alpha
A. Weidemann et al.
CELL DEATH AND DIFFERENTIATION (2008)
Oxygen sensing by metazoans: The central role of the HIF hydroxylase pathway
William G. Kaelin et al.
MOLECULAR CELL (2008)
Cytochrome c:: functions beyond respiration
Yong-Ling P. Ow et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Acute kidney injury in intensive care unit patients: a comparison between the RIFLE and the Acute Kidney Injury Network classifications
Jose Antonio Lopes et al.
CRITICAL CARE (2008)
Hypoxia-inducible factors: Crosstalk between their protein stability and protein degradation
Wei Wei et al.
CANCER LETTERS (2007)
The role of hypoxia-inducible factors in cancer
M. A. Maynard et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production
Eric L. Bell et al.
JOURNAL OF CELL BIOLOGY (2007)
Hypoxia-inducible transcription factors and their role in renal disease
Kai-Uwe Eckardt et al.
SEMINARS IN NEPHROLOGY (2007)
Hypoxia-inducible factors in the kidney
Volker H. Haase
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
Cytokine expression profile over time in severely burned pediatric patients
Celeste C. Finnerty et al.
SHOCK (2006)
Hypoxia-inducible factors, hypoxia, and tumor angiogenesis
Michaela Gruber et al.
CURRENT OPINION IN HEMATOLOGY (2006)
The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-α
F Dayan et al.
CANCER RESEARCH (2006)
HIF-1α has an anti-apoptotic effect in human airway epithelium that is mediated via Mcl-1 gene expression
XH Liu et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2006)
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
JW Kim et al.
CELL METABOLISM (2006)
Gene expression programs in response to hypoxia: Cell type specificity and prognostic significance in human cancers
JT Chi et al.
PLOS MEDICINE (2006)
Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent
MP Biju et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2005)
Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues
EJ Soilleux et al.
HISTOPATHOLOGY (2005)
Hypoxia inducible factor 1α regulates T cell receptor signal transduction
AK Neumann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mechanism of HIF-1α-dependent suppression of hypoxia-induced apoptosis in squamous cell carcinoma cells
E Sasabe et al.
CANCER SCIENCE (2005)
Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1α accumulation-implications for prolyl hydroxylase activity and iron
M Callapina et al.
EXPERIMENTAL CELL RESEARCH (2005)
Brain-specific knock-out of hypoxia-inducible factor-1α reduces rather than increases hypoxic-ischemic damage
R Helton et al.
JOURNAL OF NEUROSCIENCE (2005)
Hypoxia-mediated down-regulation of bid and bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance
JT Erler et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
BH3-only protein noxa is a mediator of hypoxic cell death induced by hypoxia-inducible factor 1α
JY Kim et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis
AE Greijer et al.
JOURNAL OF CLINICAL PATHOLOGY (2004)
JunD reduces tumor angiogenesis by protecting cells from oxidative stress
D Gerald et al.
CELL (2004)
Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor
RJ Appelhoff et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction Of β2 integrin gene expression
TQ Kong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Oxygen sensing by HIF hydroxylases
CJ Schofield et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1α in normoxia
E Berra et al.
EMBO JOURNAL (2003)
Nitric oxide impairs normoxic degradation of HIF-1α by inhibition of prolyl hydroxylases
E Metzen et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Peritubular capillary loss after mouse acute nephrotoxicity correlates with down-regulation of vascular endothelial growth factor-A and hypoxia-inducible factor-1 alpha
HT Yuan et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
Regulation of hypoxia-inducible factor-1 alpha by nitric oxide through mitochondria-dependent and -independent pathways
J Mateo et al.
BIOCHEMICAL JOURNAL (2003)
Widespread, hypoxia-inducible expression of HIF-2α in distinct cell populations of different organs
MS Wiesener et al.
FASEB JOURNAL (2002)
Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway
C Treins et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice
H Kojima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Normoxic induction of the hypoxia-inducible factor 1α by insulin and interleukin-1β involves the phosphatidylinositol 3-kinase pathway
DP Stiehl et al.
FEBS LETTERS (2002)
Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch
D Lando et al.
SCIENCE (2002)
Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions
CC Caldwell et al.
JOURNAL OF IMMUNOLOGY (2001)
Regulation of the hypoxia-inducible factor 1α by the inflammatory mediators nitric oxide and tumor necrosis factor-α in contrast to desferroxamine and phenylarsine oxide
KB Sandau et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
FIH-1:: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
PC Mahon et al.
GENES & DEVELOPMENT (2001)
Transcription factors p53 and HIF-1α as targets of nitric oxide
B Brüne et al.
CELLULAR SIGNALLING (2001)
Hypoxia induces the expression of the pro-apoptotic gene BNIP3
K Guo et al.
CELL DEATH AND DIFFERENTIATION (2001)
Skeletal muscle apoptosis after burns is associated with activation of proapoptotic signals
S Yasuhara et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2000)
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1α during hypoxia -: A mechanism of O2 sensing
NS Chandel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Nora, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
E Oda et al.
SCIENCE (2000)
Share Paper
