Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 23, Issue 9, Pages -Publisher
MDPI
DOI: 10.3390/ijms23094991
Keywords
small GTPases; GTP-binding proteins; vascular development and zebrafish
Funding
- Ministry of Science and Technology, Taiwan [MOST107-2311-B-110-002, MOST108-2313-B-110-002-MY3]
- NSYSU-KMU Joint Research Project [NSYSUKMU106-P019, NSYSUKMU107-P002]
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This article discusses the role of Ras superfamily proteins in the development of the vascular system in zebrafish.
Members of the Ras superfamily have been found to perform several functions leading to the development of eukaryotes. These small GTPases are divided into five major subfamilies, and their regulators can turn on and turn off signals. Recent studies have shown that this superfamily of proteins has various roles in the process of vascular development, such as vasculogenesis and angiogenesis. Here, we discuss the role of these subfamilies in the development of the vascular system in zebrafish.
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