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Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P
R. Lane Coffee et al.
DISEASE MODELS & MECHANISMS (2010)
Seizure Sensitivity Is Ameliorated by Targeted Expression of K+-Cl- Cotransporter Function in the Mushroom Body of the Drosophila Brain
Daria S. Hekmat-Scafe et al.
GENETICS (2010)
Increased energy metabolism rescues glia-induced pathology in a Drosophila model of Huntington's disease
Marie-Therese Besson et al.
HUMAN MOLECULAR GENETICS (2010)
Early-Onset L-dopa-Responsive Parkinsonism with Pyramidal Signs Due to ATP13A2, PLA2G6, FBXO7 and Spatacsin Mutations
Coro Paisan-Ruiz et al.
MOVEMENT DISORDERS (2010)
Interaction between RasV12 and scribbled clones induces tumour growth and invasion
Ming Wu et al.
NATURE (2010)
Inflammation A driving force speeds cancer metastasis
Yadi Wu et al.
CELL CYCLE (2009)
Adenomatous polyposis coli regulates Drosophila intestinal stem cell proliferation
Wen-Chih Lee et al.
DEVELOPMENT (2009)
Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function
Vanessa A. Morais et al.
EMBO MOLECULAR MEDICINE (2009)
Partial loss of GATA factor Pannier impairs adult heart function in Drosophila
Li Qian et al.
HUMAN MOLECULAR GENETICS (2009)
Crypt stem cells as the cells-of-origin of intestinal cancer
Nick Barker et al.
NATURE (2009)
Nardilysin regulates axonal maturation and myelination in the central and peripheral nervous system
Mikiko Ohno et al.
NATURE NEUROSCIENCE (2009)
Serial Examination of an Inducible and Reversible Dilated Cardiomyopathy in Individual Adult Drosophila
Il-Man Kim et al.
PLOS ONE (2009)
Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot-Marie-Tooth neuropathy
Erik Storkebaum et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A Computational Screen for Regulators of Oxidative Phosphorylation Implicates SLIRP in Mitochondrial RNA Homeostasis
Joshua M. Baughman et al.
PLOS GENETICS (2009)
Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype
Ouarda Taghli-Lamallem et al.
AGING CELL (2008)
Towards a Drosophila model of Hutchinson-Gilford progeria syndrome
Gemma S. Beard et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2008)
Cell competition and its possible relation to cancer
Nicholas E. Baker et al.
CANCER RESEARCH (2008)
Adenomatous polyposis coli is present near the minimal level required for accurate graded responses to the Wingless morphogen
Hassina Benchabane et al.
DEVELOPMENT (2008)
Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease
Li Qian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The PINK1/Parkin pathway regulates mitochondrial morphology
Angela C. Poole et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Opinion - Is cell competition relevant to cancer?
Eduardo Moreno
NATURE REVIEWS CANCER (2008)
hVAPB, the causative gene of a heterogeneous group of motor neuron diseases in humans, is functionally interchangeable with its Drosophila homologue DVAP-33A at the neuromuscular junction
Andrea Chai et al.
HUMAN MOLECULAR GENETICS (2008)
Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants
Michael J. Allikian et al.
HUMAN MOLECULAR GENETICS (2007)
Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities
Cheng Wang et al.
JOURNAL OF NEUROSCIENCE (2007)
Cytoplasmic and mitochondrial protein translation in axonal and dendritic terminal arborization
Takahiro Chihara et al.
NATURE NEUROSCIENCE (2007)
A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development
Ivan P. G. Moskowitz et al.
CELL (2007)
Characterization of lamin Mutation Phenotypes in Drosophila and Comparison to Human Laminopathies
Andres Munoz-Alarcon et al.
PLOS ONE (2007)
Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity
Iraj Saadat et al.
NATURE (2007)
Autism spectrum phenotype in males and females with fragile x full mutation and premutation
Sally Clifford et al.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS (2007)
KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging
Karen Ocorr et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The Drosophila notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking
Robert Jaekel et al.
DEVELOPMENTAL CELL (2006)
Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila
Brooke M. McCartney et al.
DEVELOPMENT (2006)
Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila
Tatsushi Igaki et al.
CURRENT BIOLOGY (2006)
Dietary rescue of fumble -: a Drosophila model for pantothenate-kinase-associated neurodegeneration
Y Yang et al.
JOURNAL OF INHERITED METABOLIC DISEASE (2005)
Helicobacter pylori CagA:: a new paradigm for bacterial carcinogenesis
M Hatakeyama et al.
CANCER SCIENCE (2005)
The histone H3 acetylase dGcn5 is a key player in Drosophila melanogaster metamorphosis
C Carré et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Basigin (EMMPRIN/CD147) interacts with integrin to affect cellular architecture
KD Curtin et al.
JOURNAL OF CELL SCIENCE (2005)
Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations
MG Butler et al.
JOURNAL OF MEDICAL GENETICS (2005)
Regulation of notch signaling activity
F Schweisguth
CURRENT BIOLOGY (2004)
Metal-responsive transcription factor (MTF-1) and heavy metal stress response in Drosophila and mammalian cells:: a functional comparison
K Balamurugan et al.
BIOLOGICAL CHEMISTRY (2004)
The human protein Hugl-1 substitutes for Drosophila Lethal giant larvae tumour suppressor function in vivo
D Grifoni et al.
ONCOGENE (2004)
Expression of leukemic MLL fusion proteins in Drosophila affects cell cycle control and chromosome morphology
I Muyrers-Chen et al.
ONCOGENE (2004)
Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A
S Züchner et al.
NATURE GENETICS (2004)
hScrib is a functional homologue of the Drosophila tumour suppressor Scribble
LE Dow et al.
ONCOGENE (2003)
A genetic screen in Drosophila for metastatic behavior
RA Pagliarini et al.
SCIENCE (2003)
scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila
AM Brumby et al.
EMBO JOURNAL (2003)
The tumour suppressor gene l(2)giant discs is required to restrict the activity of Notch to the dorsoventral boundary during Drosophila wing development
T Klein
DEVELOPMENTAL BIOLOGY (2003)
Phenotypic effects of familial amyotrophic lateral sclerosis mutant Sod alleles in transgenic Drosophila
RJ Mockett et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Drosophila atonal fully rescues the phenotype of Math1 null mice:: New functions evolve in new cellular contexts
VY Wang et al.
CURRENT BIOLOGY (2002)
Epithelial-mesenchymal transitions in tumour progression
JP Thiery
NATURE REVIEWS CANCER (2002)
Wnt/Wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear β-catenin-TCF complex
T Kramps et al.
CELL (2002)
Influenza virus infection induces metallothionein gene expression in the mouse liver and lung by overlapping but distinct molecular mechanisms
K Ghoshal et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
The Drosophila homolog of mammalian zinc finger factor MTF-1 activates transcription in response to heavy metals
B Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster
LT Reiter et al.
GENOME RESEARCH (2001)
Initial sequencing and analysis of the human genome
ES Lander et al.
NATURE (2001)
Fray, a Drosophila serine/threonine kinase homologous to mammalian PASK, is required for axonal ensheathment
WM Leiserson et al.
NEURON (2000)
The genome sequence of Drosophila melanogaster
MD Adams et al.
SCIENCE (2000)
Comparative genomics of the eukaryotes
GM Rubin et al.
SCIENCE (2000)
A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch1
JS Mumm et al.
MOLECULAR CELL (2000)
Regulation of JNK by Src during Drosophila development
M Tateno et al.
SCIENCE (2000)
The effect of removing the N-terminal extension of the Drosophila myosin regulatory light chain upon flight ability and the contractile dynamics of the indirect flight muscle
JR Moore et al.
BIOPHYSICAL JOURNAL (2000)