Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 23, Issue 11, Pages -Publisher
MDPI
DOI: 10.3390/ijms23116149
Keywords
erythropoiesis; 3D genome organization; transcription factors; chromatin; enhancers; signaling; globin; thalassemia; anemia; leukemia
Funding
- Laboratory of Excellence GR-Ex (Investissements d'avenir program of the French National Research Agency) [ANR-11-LABX-0051, ANR-11-IDEX-0005-02]
- Labex EpiGenMed (Investissements d'avenir program) [ANR-10-LABX-12-01]
- Fondation pour la Recherche Medicale [Equipe FRM DEQ20180339221]
Ask authors/readers for more resources
Studies on the regulatory networks and signals controlling erythropoiesis have provided valuable insights in various fields of biology, extending beyond erythroid cells. This review highlights recent discoveries and demonstrates how erythroid cell research contributes to novel concepts and advancements in genome organization, chromatin organization, signaling, and disease, with broad relevance to life sciences.
Studies of the regulatory networks and signals controlling erythropoiesis have brought important insights in several research fields of biology and have been a rich source of discoveries with far-reaching implications beyond erythroid cells biology. The aim of this review is to highlight key recent discoveries and show how studies of erythroid cells bring forward novel concepts and refine current models related to genome and 3D chromatin organization, signaling and disease, with broad interest in life sciences.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
