Journal
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volume 64, Issue 45, Pages 8640-8646Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.jafc.6b03650
Keywords
parsley and dill based teas; alkenylbenzenes; estimated daily intake; toxic equivalency factors; margin of exposure; risk assessment
Funding
- SOIT foundation (the Foundation for Stimulation of Innovation in Toxicology)
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Risk assessment of parsley and dill based teas that contain alkenylbenzenes was performed. To this end the estimated daily intake (EDI) of alkenylbenzenes resulting from use of the teas was quantified. Since most teas appeared to contain more than one alkenylbenzene, a combined risk assessment was performed based on equal potency of all alkenylbenzenes or using a so-called toxic equivalency (TEQ) approach through defining toxic equivalency factors (TEFs) for the different alkenylbenzenes. The EDI values resulting from consuming one cup of tea a day were 0.2-10.1 mu g/kg bw for the individual alkenylbenzenes, 0.6-13.1,mu g/kg bw for the sum of the alkenylbenzenes, and 0.3-10.7 mu g safrole equiv/kg bw for the sum of alkenylbenzenes when expressed in safrole equivalents. The margin of exposure (MOE) values obtained were generally <10000, indicating a concern if the teas would be consumed on a daily basis over longer periods of time.
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