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EUKARYOTIC CELL (2010)
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Exposure of Hydrophobic Surfaces Initiates Aggregation of Diverse ALS-Causing Superoxide Dismutase-1 Mutants
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MOLECULAR CELL (2010)
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NATURE CHEMICAL BIOLOGY (2010)
Huntington's disease: a clinical review
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PRION (2010)
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Biology of Amyloid: Structure, Function, and Regulation
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Molecular Modeling of the Misfolded Insulin Subunit and Amyloid Fibril
Jay H. Choi et al.
BIOPHYSICAL JOURNAL (2009)
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FEBS LETTERS (2009)
Formation of Pmel17 Amyloid Is Regulated by Juxtamembrane Metalloproteinase Cleavage, and the Resulting C-terminal Fragment Is a Substrate for γ-Secretase
Markus P. Kummer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The Functional Curli Amyloid Is Not Based on In-register Parallel β-Sheet Structure
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JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity
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Molecular Characterization of Biofilm Formation and Attachment of Salmonella enterica Serovar Typhimurium DT104 on Food Contact Surfaces
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MOLECULAR MICROBIOLOGY (2009)
Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function
John D. Simon et al.
PIGMENT CELL & MELANOMA RESEARCH (2009)
The repeat domain of the melanosome fibril protein Pmel17 forms the amyloid core promoting melanin synthesis
Ryan P. McGlinchey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF
Ashley A. Nenninger et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Distinct conformations of in vitro and in vivo amyloids of huntingtin-exon1 show different cytotoxicity
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
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Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules
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The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response
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Prediction of aggregation-prone regions in structured proteins
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Autophagy fights disease through cellular self-digestion
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Jed J. W. Wiltzius et al.
PROTEIN SCIENCE (2008)
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A general model of prion strains and their pathogenicity
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The structural basis of yeast prion strain variants
Brandon H. Toyama et al.
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Mookyung Cheon et al.
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Influence of Curli expression by Escherichia coli O157:H7 on the cell's overall hydrophobicity, charge, and ability to attach to lettuce
Renee R. Boyer et al.
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Tryptophan 32 potentiates aggregation and cytotoxicity of a copper/zinc superoxide dismutase mutant associated with familial amyotrophic lateral sclerosis
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Atomic structures of amyloid cross-β spines reveal varied steric zippers
Michael R. Sawaya et al.
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A three-stage kinetic model of amyloid fibrillation
Chuang-Chung Lee et al.
BIOPHYSICAL JOURNAL (2007)
Amyloidogenesis of type III-dependent harpins from plant pathogenic bacteria
Jonghee Oh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Functional amyloid - from bacteria to humans
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TRENDS IN BIOCHEMICAL SCIENCES (2007)
The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis
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HUMAN MOLECULAR GENETICS (2007)
Cell death by incompatibility in the fungus Podospora
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Structural principles of tau and the paired helical filaments of Alzheimer's disease
Eckhard Mandelkow et al.
BRAIN PATHOLOGY (2007)
Non-self recognition and programmed cell death in filamentous fungi
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CURRENT OPINION IN MICROBIOLOGY (2006)
Characterization of the nanoscale properties of individual amyloid fibrils
Jeffrey F. Smith et al.
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The roles of intracellular protein-degradation pathways in neurodegeneration
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Exogenous induction of cerebral β-amyloidogenesis is governed by agent and host
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TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail - An important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing
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The Silver locus product Pmel17/gp100/Silv/ME20:: controversial in name and in function
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Purification of neuronal inclusions of patients with Huntington's disease reveals a broad range of N-terminal fragments of expanded huntingtin and insoluble polymers
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Rationalising lysozyme amyloidosis: Insights from the structure and solution dynamics of T70N lysozyme
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Correlation of structural elements and infectivity of the HET-s prion
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NATURE (2005)
Role of bacterial cell surface structures in Escherichia coli biofilm formation
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Delocalization of the multifunctional RNA splicing factor TLS/FUS in hippocampal neurones: exclusion from the nucleus and accumulation in dendritic granules and spine heads
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NEUROSCIENCE LETTERS (2005)
Raft lipids as common components of human extracellular amyloid fibrils
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Self-propagating, molecular-level polymorphism in Alzheimer's β-amyloid fibrils
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Curli fibers are required for development of biofilm architecture in Escherichia coli K-12 and enhance bacterial adherence to human uroepithelial cells
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Role of curli fimbriae in mediating the cells of enterohaemorrhagic Escherichia coli to attach to abiotic surfaces
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Depletion of TDP 43 overrides the need for exonic and intronic splicing enhancers in the human apoA-II gene
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NUCLEIC ACIDS RESEARCH (2005)
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release
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MOLECULAR MICROBIOLOGY (2004)
Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers
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FEBS LETTERS (2004)
The Dominant white, Dun and Smoky color variants in chicken are associated with insertion/deletion polymorphisms in the PMEL17 gene
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Domain Architectures and characterization of an RNA-binding protein, TLS
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JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Evidence for assembly of prions with left-handed β3-helices into trimers
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Emerging principles of conformation based prion inheritance
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ANNUAL REVIEW OF BIOCHEMISTRY (2004)
Stages in the development of Parkinson's disease-related pathology
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CELL AND TISSUE RESEARCH (2004)
A neuronal isoform of the Aplysia CPEB has prion-like properties
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CELL (2003)
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CELL (2003)
α-synuclein locus triplication causes Parkinson's disease
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Rationalization of the effects of mutations on peptide and protein aggregation rates
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The chaplins:: a family of hydrophobic cell-surface proteins involved in aerial mycelium formation in Streptomyces coelicolor
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GENES & DEVELOPMENT (2003)
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GENES & DEVELOPMENT (2003)
Sexual transmission of the [Het-s] prion leads to meiotic drive in Poldospora anserina
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Proprotein convertase cleavage liberates a fibrillogenic fragment of a resident glycoprotein to initiate melanosome biogenesis
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Domain organization and structure-function relationship of the HET-s prion protein of Podospora anserina
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EMBO JOURNAL (2003)
Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells
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JOURNAL OF CELL BIOLOGY (2003)
Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution
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JOURNAL OF MOLECULAR MEDICINE-JMM (2003)
Molecular conformation of a peptide fragment of transthyretin in an amyloid fibril
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Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines
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The protofilament structure of insulin amyloid fibrils
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Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties
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Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
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Microcin E492, a channel-forming bacteriocin from Klebsiella pneumoniae, induces apoptosis in some human cell lines
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
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Role of Escherichia coli curli operons in directing amyloid fiber formation
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Isolation of a 40-kDa Huntingtin-associated protein
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A hydrophobic stretch of 12 amino acid residues in the middle of α-synuclein is essential for filament assembly
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