4.0 Article

Liver transcriptome analysis reveals biological pathways and transcription factors in response to high ammonia exposure

Related references

Note: Only part of the references are listed.
Article Agriculture, Dairy & Animal Science

Effects of dietary inclusion of Radix Bupleuri extract on the growth performance, and ultrastructural changes and apoptosis of lung epithelial cells in broilers exposed to atmospheric ammonia

Shiping Bai et al.

Summary: The experiment demonstrated that ammonia exposure led to decreased body weight gain and feed intake in broilers, while supplementation with Radix Bupleuri extract (RBE) reduced feed consumption under NH70 conditions. At the cellular level, RBE addition alleviated intercellular ultrastructural damage induced by NH3 exposure.

JOURNAL OF ANIMAL SCIENCE (2021)

Article Biochemistry & Molecular Biology

ACTG1 regulates intervertebral disc degeneration via the NF- kB-p65 and Akt pathways

Tongde Wu et al.

Summary: ACTG1 gene mutation leads to hearing loss in humans and is involved in regulating tumor cell proliferation and migration, as well as playing an important role in intervertebral disc degeneration. The expression of ACTG1 gene is negatively correlated with the severity of disc degeneration, and the absence of ACTG1 exacerbates IDD development.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2021)

Article Biochemistry & Molecular Biology

UBXN7 cofactor of CRL3KEAP1 and CRL2VHL ubiquitin ligase complexes mediates reciprocal regulation of NRF2 and HIF-1α proteins

Jacopo Di Gregorio et al.

Summary: UBXN7 is a cofactor protein that regulates the protein levels of NRF2 and HIF-1α, and coordinates the activity of CRL3(KEAP1) and CRL2(VHL) ubiquitin ligase complexes under conditions of oxidative stress or hypoxia. This regulation leads to different metabolic states and adaptive responses to mitochondrial stress.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2021)

Article Environmental Sciences

Excessive ammonia inhalation causes liver damage and dysfunction by altering gene networks associated with oxidative stress and immune function

Xiangyin Zeng et al.

Summary: This study found that excessive NH3 inhalation had effects on the transcriptional profiles and liver function in fattening pigs, leading to oxidative stress and immune dysfunction, which resulted in liver damage. The study not only provided a new perspective for assessing the toxicity of NH3, but also enriched the toxicological mechanism of NH3.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021)

Article Agriculture, Dairy & Animal Science

Effect of dietary coarse corn inclusion on broiler live performance, litter characteristics, and ammonia emission

Lingjuan Wang-Li et al.

POULTRY SCIENCE (2020)

Article Surgery

Porcine Liver Anatomy Applied to Biomedicine

Lada Eberlova et al.

JOURNAL OF SURGICAL RESEARCH (2020)

Article Biochemistry & Molecular Biology

COX10-AS1 Facilitates Cell Proliferation and Inhibits Cell Apoptosis in Glioblastoma Cells at Post-Transcription Level

Chaoyang Zhou et al.

NEUROCHEMICAL RESEARCH (2020)

Article Environmental Sciences

Oxidative stress and mitochondrial dysfunction involved in ammonia-induced nephrocyte necroptosis in chickens

Qi Han et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2020)

Article Environmental Sciences

Ammonia exposure causes lung injuries and disturbs pulmonary circadian clock gene network in a pig study

Xiaotong Wang et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2020)

Article Multidisciplinary Sciences

Ammonia exposition during gestation induces neonatal oxidative damage in the brain and long-term cognitive alteration in rats

Diogo Dominguini et al.

ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS (2020)

Article Biochemistry & Molecular Biology

AnimalTFDB 3.0: a comprehensive resource for annotation and prediction of animal transcription factors

Hui Hu et al.

NUCLEIC ACIDS RESEARCH (2019)

Article Agriculture, Dairy & Animal Science

The evaluation of potential immunotoxicity induced by environmental pollutant ammonia in broilers

Yang An et al.

POULTRY SCIENCE (2019)

Article Environmental Sciences

Ammonia induces Treg/Th1 imbalance with triggered NF-κB pathway leading to chicken respiratory inflammation response

Qunxiang Shi et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2019)

Article Environmental Sciences

The co-expression of circRNA and mRNA in the thymuses of chickens exposed to ammonia

Dechun Chen et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2019)

Article Biochemistry & Molecular Biology

TRRUST v2: an expanded reference database of human and mouse transcriptional regulatory interactions

Heonjong Han et al.

NUCLEIC ACIDS RESEARCH (2018)

Review Gastroenterology & Hepatology

Circadian Clock Control of Liver Metabolic Functions

Hans Reinke et al.

GASTROENTEROLOGY (2016)

Article Biochemical Research Methods

HTSeq-a Python framework to work with high-throughput sequencing data

Simon Anders et al.

BIOINFORMATICS (2015)

Article Biochemistry & Molecular Biology

STRING v10: protein-protein interaction networks, integrated over the tree of life

Damian Szklarczyk et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Agriculture, Dairy & Animal Science

Chronic ammonia exposure does not influence hepatic gene expression in growing pigs

Z. Cheng et al.

ANIMAL (2014)

Article Biochemical Research Methods

circlize implements and enhances circular visualization in R

Zuguang Gu et al.

BIOINFORMATICS (2014)

Article Mathematical & Computational Biology

cytoHubba: identifying hub objects and sub-networks from complex interactome

Chia-Hao Chin et al.

BMC SYSTEMS BIOLOGY (2014)

Article Biotechnology & Applied Microbiology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love et al.

GENOME BIOLOGY (2014)

Article Endocrinology & Metabolism

Ammonia toxicity to the brain

Olivier Braissant et al.

JOURNAL OF INHERITED METABOLIC DISEASE (2013)

Article Pharmacology & Pharmacy

Application of ggplot2 to Pharmacometric Graphics

K. Ito et al.

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2013)

Article Biochemistry & Molecular Biology

ATF3 inhibits adipocyte differentiation of 3T3-L1 cells

Min Kyung Jang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

Article Biochemical Research Methods

Fast gapped-read alignment with Bowtie 2

Ben Langmead et al.

NATURE METHODS (2012)

Article Biotechnology & Applied Microbiology

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

Guangchuang Yu et al.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2012)

Article Ophthalmology

HIF1A Is Essential for the Development of the Intermediate Plexus of the Retinal Vasculature

Christian Caprara et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)

Article Agriculture, Dairy & Animal Science

GENE EXPRESSION OF HEPATIC GLUCOCORTICOID RECEPTOR NR3C1 AND CORRELATION WITH PLASMATIC CORTICOSTERONE IN ITALIAN CHICKENS

S. P. Marelli et al.

ANIMAL BIOTECHNOLOGY (2010)

Article Immunology

Fos Proteins Suppress Dextran Sulfate Sodium-Induced Colitis through Inhibition of NF-κB

Yasunari Takada et al.

JOURNAL OF IMMUNOLOGY (2010)

Article Biochemical Research Methods

TopHat: discovering splice junctions with RNA-Seq

Cole Trapnell et al.

BIOINFORMATICS (2009)

Article Gastroenterology & Hepatology

Blood ammonia levels in liver cirrhosis: a clue for the presence of portosystemic collateral veins

Giovanni Tarantino et al.

BMC GASTROENTEROLOGY (2009)

Review Immunology

Microanatomy of the liver immune system

Eszter Nemeth et al.

SEMINARS IN IMMUNOPATHOLOGY (2009)

Article Gastroenterology & Hepatology

Lack of association of the 3′-UTR polymorphism in the NFKBIA gene with Crohn's disease in an Israeli cohort

E. Leshinsky-Silver et al.

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE (2007)

Review Gastroenterology & Hepatology

Does stress exacerbate liver diseases?

Y Chida et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2006)

Article Psychology, Developmental

A non-accidental poisoning with ammonia in adolescence

D Dilli et al.

CHILD CARE HEALTH AND DEVELOPMENT (2005)

Article Multidisciplinary Sciences

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

A Subramanian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Endocrinology & Metabolism

Metabolomic analysis of adrenal lipids during hypoxia in the neonatal rat: implications in steroidogenesis

ED Bruder et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)

Article Biochemistry & Molecular Biology

Cytoscape: A software environment for integrated models of biomolecular interaction networks

P Shannon et al.

GENOME RESEARCH (2003)