Journal
INDIAN JOURNAL OF PEDIATRICS
Volume 89, Issue 10, Pages 1031-1033Publisher
SPRINGER INDIA
DOI: 10.1007/s12098-022-04170-8
Keywords
Rituximab; Encephalitis; Herpes simplex virus; Anti-N-methyl-D-aspartate-receptor
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Funding
- Mutua Madrilena Foundation Award [AP162572016]
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This article reports the long-term response of two infants with anti-N-methyl-D-aspartate receptor (anti-NMDAR) post herpes simplex encephalitis treated with rituximab. Rituximab may improve the course of the disease and should be considered early as a second-line treatment. Data on the long-term effect of rituximab in B cell depletion and immunoglobulins levels in infants are needed.
The long-term response of two infants with anti-N-methyl-D-aspartate receptor (anti-NMDAR) post herpes simplex encephalitis treated with rituximab is reported here. Rituximab may improve the course of the disease and should be considered early as second-line treatment. Data on the long-term effect of rituximab in B cell depletion and immunoglobulins levels in infants are needed.
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