Journal
IMMUNITY
Volume 55, Issue 5, Pages 735-737Publisher
CELL PRESS
DOI: 10.1016/j.immuni.2022.04.014
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- Institute for Basic Science (IBS) , Republic of Korea [IBS-R801-D2]
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This study revealed that human KIR(+)CD8(+) T cells suppress autoimmunity by eliminating pathogenic CD4(+) T cells.
Identification of regulatory CD8(+) T cells that suppress pathological immune responses is an importunate pursuit. In a recent issue of Science, Li et al. demonstrated that human KIR(+)CD8(+) T cells suppress autoimmunity by eliminating pathogenic CD4(+) T cells.
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