4.7 Article

T3-induced enhancement of mitochondrial Ca2+ uptake as a boost for mitochondrial metabolism

Related references

Note: Only part of the references are listed.
Article Cell Biology

Dynamic Control of Mitochondrial Ca2+ Levels as a Survival Strategy of Cancer Cells

Corina T. Madreiter-Sokolowski et al.

Summary: Cancer cells have increased energy demands and maintaining mitochondrial Ca2+ homeostasis is crucial for their survival. The ER-mitochondrial linkage and UCP2 play key roles in the mitochondrial Ca2+ uptake route in cancer cells. Disrupting the balance of these factors can lead to cancer cell death.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Biochemistry & Molecular Biology

Thyroid Hormone Induces Ca2+-Mediated Mitochondrial Activation in Brown Adipocytes

Minh-Hanh Thi Nguyen et al.

Summary: Short-term exposure to T-3 induces UCP1 upregulation and mitochondrial activation in brown adipocytes through PLC-mediated elevation of [Ca2+].

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Biochemistry & Molecular Biology

Protein arginine methyltransferase 1 regulates cell proliferation and differentiation in adult mouse adult intestine

Lu Xue et al.

Summary: Adult stem cells are crucial in organ physiology and tissue repair, yet the mechanisms of their development remain unclear. PRMT1, a coactivator of T3 receptor, is highly expressed during intestinal maturation. Knockout of PRMT1 in the intestine surprisingly leads to increased cell proliferation and changes in cell types in the crypt, indicating a potential regulation beyond T3-signaling in intestinal development.

CELL AND BIOSCIENCE (2021)

Article Biochemistry & Molecular Biology

Sigma-1 Receptor Promotes Mitochondrial Bioenergetics by Orchestrating ER Ca2+ Leak during Early ER Stress

Zhanat Koshenov et al.

Summary: The endoplasmic reticulum (ER) is a vital organelle responsible for processing and trafficking nearly 30% of human proteins. ER stress can trigger a response called unfolded protein response (UPR) to restore ER functions. The Sigma-1 receptor (S1R) plays a crucial role in enhancing mitochondrial bioenergetics during early ER stress by directing enhanced ER Ca2+ leak towards mitochondria.

METABOLITES (2021)

Review Multidisciplinary Sciences

Mitochondrial TCA cycle metabolites control physiology and disease

Inmaculada Martinez-Reyes et al.

NATURE COMMUNICATIONS (2020)

Review Biochemistry & Molecular Biology

Interrelation between ROS and Ca2+ in aging and age-related diseases

Corina T. Madreiter-Sokolowski et al.

REDOX BIOLOGY (2020)

Review Physiology

Important Trends in UCP3 Investigation

Elena E. Pohl et al.

FRONTIERS IN PHYSIOLOGY (2019)

Article Multidisciplinary Sciences

MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex

Benjamin Gottschalk et al.

NATURE COMMUNICATIONS (2019)

Article Biochemistry & Molecular Biology

N-Acetylcysteine as an antioxidant and disulphide breaking agent: the reasons why

Giancarlo Aldini et al.

FREE RADICAL RESEARCH (2018)

Review Biochemistry & Molecular Biology

Use the Protonmotive Force: Mitochondrial Uncoupling and Reactive Oxygen Species

Brandon J. Berry et al.

JOURNAL OF MOLECULAR BIOLOGY (2018)

Review Endocrinology & Metabolism

Metabolic Effects of the Intracellular Regulation of Thyroid Hormone: Old Players, New Concepts

Annunziata G. Cicatiello et al.

FRONTIERS IN ENDOCRINOLOGY (2018)

Article Biochemistry & Molecular Biology

Intact mitochondrial Ca2+ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS)

Suphachai Charoensin et al.

FREE RADICAL BIOLOGY AND MEDICINE (2017)

Article Biochemistry & Molecular Biology

Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity

Zhiwei Dong et al.

MOLECULAR CELL (2017)

Article Multidisciplinary Sciences

Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo

G. Sebastian Hoenes et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Oncology

UCP2 and PRMT1 are key prognostic markers for lung carcinoma patients

Corina T. Madreiter-Sokolowski et al.

ONCOTARGET (2017)

Article Biochemical Research Methods

Quantifying ROS levels using CM-H2DCFDA and HyPer

Monika Oparka et al.

METHODS (2016)

Article Multidisciplinary Sciences

PRMT1-mediated methylation of MICU1 determines the UCP2/3 dependency of mitochondrial Ca2+ uptake in immortalized cells

Corina T. Madreiter-Sokolowski et al.

NATURE COMMUNICATIONS (2016)

Review Cardiac & Cardiovascular Systems

The Ins and Outs of Mitochondrial Calcium

Toren Finkel et al.

CIRCULATION RESEARCH (2015)

Article Medical Laboratory Technology

Single-Dose T3 Administration: Kinetics and Effects on Biochemical and Physiological Parameters

Jacqueline Jonklaas et al.

THERAPEUTIC DRUG MONITORING (2015)

Article Cardiac & Cardiovascular Systems

Effects of continuous triiodothyronine infusion on the tricarboxylic acid cycle in the normal immature swine heart under extracorporeal membrane oxygenation in vivo

Masaki Kajimoto et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2014)

Review Biochemistry & Molecular Biology

Inositol 1,4,5-trisphosphate receptor-isoform diversity in cell death and survival

Hristina Ivanova et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)

Review Endocrinology & Metabolism

Defending plasma T3 is a biological priority

Sherine M. Abdalla et al.

CLINICAL ENDOCRINOLOGY (2014)

Review Physiology

THYROID HORMONE REGULATION OF METABOLISM

Rashmi Mullur et al.

PHYSIOLOGICAL REVIEWS (2014)

Review Physiology

MITOCHONDRIAL REACTIVE OXYGEN SPECIES (ROS) AND ROS-INDUCED ROS RELEASE

Dmitry B. Zorov et al.

PHYSIOLOGICAL REVIEWS (2014)

Article Multidisciplinary Sciences

UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation

Angelo Vozza et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Cell Biology

PGC-1α buffers ROS-mediated removal of mitochondria during myogenesis

S. Baldelli et al.

CELL DEATH & DISEASE (2014)

Article Multidisciplinary Sciences

Gene Specific Actions of Thyroid Hormone Receptor Subtypes

Jean Z. Lin et al.

PLOS ONE (2013)

Review Endocrinology & Metabolism

The role of thyroid hormone and brown adipose tissue in energy homoeostasis

Antonio C. Bianco et al.

LANCET DIABETES & ENDOCRINOLOGY (2013)

Article Biochemistry & Molecular Biology

Depletion of the p43 mitochondrial T3 receptor in mice affects skeletal muscle development and activity

Laurence Pessemesse et al.

FASEB JOURNAL (2012)

Review Biochemistry & Molecular Biology

Uncoupling proteins and the control of mitochondrial reactive oxygen species production

Ryan J. Mailloux et al.

FREE RADICAL BIOLOGY AND MEDICINE (2011)

Article Biochemistry & Molecular Biology

Rapid turnover of mitochondrial uncoupling protein 3

Vian Azzu et al.

BIOCHEMICAL JOURNAL (2010)

Article Biochemistry & Molecular Biology

Redox-optimized ROS balance: A unifying hypothesis

M. A. Aon et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2010)

Article Endocrinology & Metabolism

Reduced Expression of Uncoupling Protein 2 in Adipose Tissue in Patients with Hypothyroidism

Signe Gjedde et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)

Review Biochemistry & Molecular Biology

Regulation of mitochondrial dehydrogenases by calcium ions

Richard M. Denton

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)

Article Cell Biology

T3-mediated expression of PGC-1α via a far upstream located thyroid hormone response element

Anne Wulf et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2008)

Article Cell Biology

Uncoupling proteins 2 and 3 are fundamental for mitochondrial Ca2+ uniport

Michael Trenker et al.

NATURE CELL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

UCP2 is a mitochondrial transporter with an unusual very short half-life

Sophie Rousset et al.

FEBS LETTERS (2007)

Article Cardiac & Cardiovascular Systems

Nuclear-mitochondrial cross-talk in cardiomyocyte T3 signaling:: A time-course analysis

MJ Goldenthal et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2005)

Review Cell Biology

Calcium, ATP, and ROS: a mitochondrial love-hate triangle

PS Brookes et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)

Article Nutrition & Dietetics

The role of uncoupling protein 3 in fatty acid metabolism: protection against lipotoxicity?

P Schrauwen et al.

PROCEEDINGS OF THE NUTRITION SOCIETY (2004)

Review Biochemistry & Molecular Biology

Thyroid hormone and uncoupling proteins

A Lanni et al.

FEBS LETTERS (2003)

Article Biochemistry & Molecular Biology

Thyroid hormone may induce changes in the concentration of the mitochondrial calcium uniporter

SG Robles et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Two thyroid hormone-mediated gene expression patterns in vivo identified by cDNA expression arrays in rat

JM Weitzel et al.

NUCLEIC ACIDS RESEARCH (2001)

Article Endocrinology & Metabolism

T3 increases mitochondrial ATP production in oxidative muscle despite increased expression of UCP2 and-3

KR Short et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2001)