Covalent organic framework reinforced hollow fiber for solid-phase microextraction and determination of pesticides in foods

A novel solid-phase micro extraction (SPME) system was constructed by immobilizing a three-dimensional hydroxyl-functionalized covalent organic framework (COF) into the wall pores of hollow fiber (HF). The extractant was sensitive to hydrogen bond acceptors contained analytes. Combined with high performance liquid chromatography (HPLC), a SPME-HPLC method was established for acetamiprid (Ace), dimethipin (Dim), and amitrole (Ami) simultaneous determination from rice and apple samples. Critical extraction parameters were optimized. The analytical method was proved to have good linearity with the linear coefficients above 0.99, satisfactory precision with the RSD less than 4.9%, desirable recovery ranged from 79.3% to 106.8%, and low limit of detection (LOD) ranged from 0.86 to 1.38 ng/g for Ace, Dim, and Ami. The explored analytical method has potentials for hydrogen bond acceptors contained pesticides sensitive and selective determination from food samples.

Automated summary

A novel SPME-HPLC method was developed for the simultaneous determination of Ace, Dim, and Ami from rice and apple samples. The critical extraction parameters were optimized, and the method showed good linearity, precision, and recovery. The analytical method has potential for sensitive and selective determination of pesticides containing hydrogen bond acceptors from food samples.