Association between infection with Toxoplasma gondii and psychiatric disorders

Toxoplasmosis is one of the world's most prevalent zoonoses. The causative agent, Toxoplasma gondii (Nicolle et Manceaux, 1908) is a facultative heteroxenic, polyxenic apicomplexan protist. There are several potential pathways of transmission within and be-tween host species. Most infections with T. gondii result from close contact with pets/cats, ingestion of tissue cysts in undercooked meat of infected animals, and oocysts from food or water contaminated by feline faeces. Recently, epidemiological studies have shown that T. gondii infection plays a prominent role in the pathogenesis of several psychiatric disorders. This report reviews the association be-tween T. gondii infection and patients with psychiatric disorders, particularly schizophrenia, depressive disorders and bipolar disorders.

Automated summary

Toxoplasmosis is a prevalent zoonotic disease caused by the parasite Toxoplasma gondii. Transmission can occur through close contact with pets/cats, ingestion of undercooked meat or food/water contaminated by cat feces. Recent studies have shown an association between T. gondii infection and psychiatric disorders, particularly schizophrenia, depressive disorders, and bipolar disorders.