4.7 Article

The forkhead box O transcription factor regulates lipase and anti-microbial peptide expressions to promote lipid catabolism and improve innate immunity in the Eriocheir sinensis with hepatopancreatic necrosis disease

Related references

Note: Only part of the references are listed.
Article Fisheries

Toll-crustin signaling pathway is activated in the Eriocheir sinensis with hepatopancreatic necrosis disease (HPND)

Ximei Nie et al.

Summary: In this study, we investigated the effects of HPND on the innate immune regulation in Chinese mitten crab and found that the Toll-crustin signaling pathway is activated in diseased crabs. Our findings provide new insights for HPND research.

AQUACULTURE (2022)

Article Biology

Metatranscriptomic Analysis Reveals an Imbalance of Hepatopancreatic Flora of Chinese Mitten Crab Eriocheir sinensis with Hepatopancreatic Necrosis Disease

Zeen Shen et al.

Summary: The imbalance of hepatopancreatic flora is associated with Chinese mitten crab Eriocheir sinensis hepatopancreas necrosis disease (HPND), and the enriched pathways of differentially-expressed genes (DEGs) are related to the pathological mechanism of HPND. Additionally, virus and microsporidia did not seem to play a significant role in the occurrence of HPND.

BIOLOGY-BASEL (2021)

Article Toxicology

Acute exposure to microcystin-LR induces hepatopancreas toxicity in the Chinese mitten crab (Eriocheir sinensis)

Cheng Chi et al.

Summary: Chinese mitten crab is economically important in aquaculture, but hepatopancreatic necrosis syndrome caused by cyanobacteria bloom outbreaks and MC-LR toxicity can affect its quality and breeding industry.

ARCHIVES OF TOXICOLOGY (2021)

Article Microbiology

FOXO regulates the expression of antimicrobial peptides and promotes phagocytosis of hemocytes in shrimp antibacterial immunity

Cang Li et al.

Summary: This study identified the involvement of FOXO in systemic and cellular immunity regulation in invertebrates, specifically in shrimp. FOXO plays a critical role in maintaining hemolymph and intestinal microbiota homeostasis by promoting the expression of antimicrobial peptides and enhancing phagocytosis of hemocytes against pathogens. The study revealed the different functions of FOXO in mucosal and systemic antibacterial immunity of invertebrates, providing insights for disease prevention and control in aquaculture.

PLOS PATHOGENS (2021)

Article Environmental Sciences

Evaluation of pathology and environmental variables contributing to hepatopancreatic necrosis syndrome of Chinese mitten crab, Eriocheir sinensis

Xiaoli Huang et al.

Summary: Hepatopancreatic Necrosis Syndrome (HPNS) severely impacts the Chinese mitten crab industry, with limited understanding of its etiology and pathogenesis. The study revealed that HPNS primarily affects the hepatopancreas and muscles of crabs, showing characteristics such as non-interstitial atrophic hepatopathy and lesions. Research suggests that environmental factors and nutrition deficiency play a significant role in the development of HPNS.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2021)

Article Biochemistry & Molecular Biology

Regulation of antimicrobial peptide genes via insulin-like signaling pathway in the silkworm Bombyx mori

Jie Zhang et al.

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY (2018)

Review Endocrinology & Metabolism

Monoacylglycerol signalling and ABHD6 in health and disease

Pegah Poursharifi et al.

DIABETES OBESITY & METABOLISM (2017)

Review Genetics & Heredity

Genome-wide identification and characterization of Fox genes in the silkworm, Bombyx mori

JiangBo Song et al.

FUNCTIONAL & INTEGRATIVE GENOMICS (2015)

Review Cell & Tissue Engineering

Concise Review: Forkhead Pathway in the Control of Adult Neurogenesis

Emmanuelle C. Genin et al.

STEM CELLS (2014)

Article Biochemistry & Molecular Biology

20-Hydroxyecdysone-induced transcriptional activity of FoxO upregulates brummer and acid lipase-1 and promotes lipolysis in Bombyx fat body

Muktadir S. Hossain et al.

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY (2013)

Review Cell Biology

FOXOs: signalling integrators for homeostasis maintenance

Astrid Eijkelenboom et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)

Review Endocrinology & Metabolism

FoxO1, the transcriptional chief of staff of energy metabolism

Stavroula Kousteni

Article Fisheries

A novel type III crustin (CrusEs2) identified from Chinese mitten crab Eriocheir sinensis

Changkao Mu et al.

FISH & SHELLFISH IMMUNOLOGY (2011)

Review Zoology

Viral diseases in commercially exploited crabs: A review

Jean-Robert Bonami et al.

JOURNAL OF INVERTEBRATE PATHOLOGY (2011)

Review Zoology

Bacterial diseases of crabs: A review

W. Wang

JOURNAL OF INVERTEBRATE PATHOLOGY (2011)

Article Genetics & Heredity

Effect of fasting on digestive gland lipase transcripts expression in Penaeus vannamei

Crisalejandra Rivera-Perez et al.

MARINE GENOMICS (2011)

Review Oncology

Understanding FOXO, New Views on Old Transcription Factors

F. Zanella et al.

CURRENT CANCER DRUG TARGETS (2010)

Article Fisheries

Molecular characterization and expression of a crustin-like gene from Chinese mitten crab, Eriocheir sinensis

Changkao Mu et al.

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2010)

Article Multidisciplinary Sciences

FOXO-dependent regulation of innate immune homeostasis

Thomas Becker et al.

NATURE (2010)

Review Fisheries

Crustins: Enigmatic WAP domain-containing antibacterial proteins from crustaceans

Valerie J. Smith et al.

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY (2008)

Review Biochemistry & Molecular Biology

The FoxO code

D. R. Calnan et al.

ONCOGENE (2008)

Article Multidisciplinary Sciences

Tissue entrainment by feedback regulation of insulin gene expression in the endoderm of Caenorhabditis elegans

Coleen T. Murphy et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Review Immunology

The intricate interface between immune system and metabolism

G Matarese et al.

TRENDS IN IMMUNOLOGY (2004)

Review Biochemistry & Molecular Biology

The triglyceride lipases of the pancreas

ME Lowe

JOURNAL OF LIPID RESEARCH (2002)

Article Biochemistry & Molecular Biology

Kinetic behavior of the pancreatic lipase-colipase-lipid system

HL Brockman

BIOCHIMIE (2000)

Article Biochemistry & Molecular Biology

Properties and function of pancreatic lipase related protein 2

ME Lowe

BIOCHIMIE (2000)