Related references
Note: Only part of the references are listed.USP28 and USP25 are downregulated by Vismodegib in vitro and in colorectal cancer cell lines
Hui Wang et al.
FEBS JOURNAL (2021)
USP2-Related Cellular Signaling and Consequent Pathophysiological Outcomes
Hiroshi Kitamura et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma
E. Josue Ruiz et al.
ELIFE (2021)
The role of the deubiquitinating enzyme DUB3/USP17 in cancer: a narrative review
Guang-Fei Yang et al.
CANCER CELL INTERNATIONAL (2021)
Proteasome Inhibitor Drugs
Lloyd D. Fricker
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 60 (2020)
Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2
Wenyang Li et al.
GENES & DEVELOPMENT (2020)
Inhibition of USP2 eliminates cancer stem cells and enhances TNBC responsiveness to chemotherapy
Jiabei He et al.
CELL DEATH & DISEASE (2019)
A Novel Mechanism Driving Poor-Prognosis Prostate Cancer: Overexpression of the DNA Repair Gene, Ribonucleotide Reductase Small Subunit M2 (RRM2)
Ying Z. Mazzu et al.
CLINICAL CANCER RESEARCH (2019)
USP7: Structure, substrate specificity, and inhibition
Alexandra Pozhidaeva et al.
DNA REPAIR (2019)
Structural and functional studies of USP20 ZnF-UBP domain by NMR
Yuanyuan Yang et al.
PROTEIN SCIENCE (2019)
Functional analysis of deubiquitylating enzymes in tumorigenesis and development
Ji Cheng et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2019)
From Discovery to Bedside: Targeting the Ubiquitin System
Ingrid E. Wertz et al.
CELL CHEMICAL BIOLOGY (2019)
Deubiquitylating enzymes and drug discovery: emerging opportunities
Jeanine A. Harrigan et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Identification of small-molecule inhibitors of USP2a
Marcin D. Tomala et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability
Dominika Kwasna et al.
MOLECULAR CELL (2018)
Targeting deubiquitinase USP28 for cancer therapy
Xiaofang Wang et al.
CELL DEATH & DISEASE (2018)
6-Thioguanine is a noncompetitive and slow binding inhibitor of human deubiquitinating protease USP2
Shang-Ju Chuang et al.
SCIENTIFIC REPORTS (2018)
USP2a Supports Metastasis by Tuning TGF-beta Signaling
Yin Zhao et al.
CELL REPORTS (2018)
The Molecular Mechanisms of Regulation on USP2's Alternative Splicing and the Significance of Its Products
Han-Qing Zhu et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2017)
Ubiquitin carboxyl-terminal hydrolases: involvement in cancer progression and clinical implications
Ying Fang et al.
CANCER AND METASTASIS REVIEWS (2017)
Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a
Katarzyna Magiera et al.
CELL CHEMICAL BIOLOGY (2017)
Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models
Mindy I. Davis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes
Syed Arif Abdul Rehman et al.
MOLECULAR CELL (2016)
Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins
Carlos A. Castaneda et al.
STRUCTURE (2016)
Deubiquitinase inhibition as a cancer therapeutic strategy
Padraig D'Arcy et al.
PHARMACOLOGY & THERAPEUTICS (2015)
The Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In Vitro
Mei-Chuan Chen et al.
MOLECULAR PHARMACOLOGY (2015)
Development of inhibitors in the ubiquitination cascade
Wei Zhang et al.
FEBS LETTERS (2014)
A Small-Molecule Blocking Ribonucleotide Reductase Holoenzyme Formation Inhibits Cancer Cell Growth and Overcomes Drug Resistance
Bingsen Zhou et al.
CANCER RESEARCH (2013)
The ubiquitin-specific protease USP2a prevents endocytosis-mediated EGFR degradation
Z. Liu et al.
ONCOGENE (2013)
MDM2, MDMX and p53 in oncogenesis and cancer therapy
Mark Wade et al.
NATURE REVIEWS CANCER (2013)
USP2a Protein Deubiquitinates and Stabilizes the Circadian Protein CRY1 in Response to Inflammatory Signals
Xin Tong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Activity-Based Chemical Proteomics Accelerates Inhibitor Development for Deubiquitylating Enzymes
Mikael Altun et al.
CHEMISTRY & BIOLOGY (2011)
Ubiquitin-specific Cysteine Protease 2a (USP2a) Regulates the Stability of Aurora-A
Yan Shi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cyclin D as a therapeutic target in cancer
Elizabeth A. Musgrove et al.
NATURE REVIEWS CANCER (2011)
What Determines the Specificity and Outcomes of Ubiquitin Signaling?
Fumiyo Ikeda et al.
CELL (2010)
Targeting the degradation of cyclin D1 will help to eliminate oncogene addiction
James T. Lee et al.
CELL CYCLE (2010)
Emerging Roles of Deubiquitinases in Cancer-Associated Pathways
Joseph J. Sacco et al.
IUBMB LIFE (2010)
MdmX is a substrate for the deubiquitinating enzyme USP2a
N. Allende-Vega et al.
ONCOGENE (2010)
The ubiquitin pathway: An emerging drug target in cancer therapy
Sudharsana Rao Ande et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Suppression of Cancer Cell Growth by Promoting Cyclin D1 Degradation
Jing Shan et al.
MOLECULAR CELL (2009)
Breaking the chains: structure and function of the deubiquitinases
David Komander et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
GSK-3 beta regulates cyclin D1 expression: A new target for chemotherapy
Fumi Takahashi-Yanaga et al.
CELLULAR SIGNALLING (2008)
Mechanisms, biology and inhibitors of deubiquitinating enzymes
Kerry Routenberg Love et al.
NATURE CHEMICAL BIOLOGY (2007)
The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2
Lauren F. Stevenson et al.
EMBO JOURNAL (2007)
The many ways of Wnt in cancer
Paul Polakis
CURRENT OPINION IN GENETICS & DEVELOPMENT (2007)
The isopeptidase USP2a protects human prostate cancer from apoptosis
Carmen Priolo et al.
CANCER RESEARCH (2006)
Structural basis of ubiquitin recognition by the deubiquitinating protease USP2
Martin Renatus et al.
STRUCTURE (2006)
A genomic and functional inventory of deubiquitinating enzymes
SMB Nijman et al.
CELL (2005)
The isopeptidase USP2a regulates the stability of fatty acid synthase in prostate cancer
E Graner et al.
CANCER CELL (2004)
Investigation of the binding constant and stoichiometry of biocompatible cobalt ferrite-based magnetic fluids to serum albumin
AC Tedesco et al.
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2004)
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
MH Glickman et al.
PHYSIOLOGICAL REVIEWS (2002)
Share Paper
