Related references
Note: Only part of the references are listed.Paclitaxel mitigates structural alterations and cardiac conduction system defects in a mouse model of Hutchinson-Gilford progeria syndrome
Alvaro Macias et al.
CARDIOVASCULAR RESEARCH (2022)
Hutchinson-Gilford progeria syndrome: Rejuvenating old drugs to fight accelerated ageing
Solenn M. Guilbert et al.
METHODS (2021)
Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation
Jonathan H. Shrimp et al.
ACS MEDICINAL CHEMISTRY LETTERS (2021)
Interleukin-6 neutralization ameliorates symptoms in prematurely aged mice
Stefano Squarzoni et al.
AGING CELL (2021)
Farnesyltransferase inhibition in HGPS
Tom Misteli
CELL (2021)
Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome
Amanda Sanchez-Lopez et al.
CIRCULATION (2021)
In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice
Luke W. Koblan et al.
NATURE (2021)
Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford progeria syndrome
So-mi Kang et al.
COMMUNICATIONS BIOLOGY (2021)
Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson-Gilford progeria syndrome
Madaiah Puttaraju et al.
NATURE MEDICINE (2021)
A targeted antisense therapeutic approach for Hutchinson-Gilford progeria syndrome
Michael R. Erdos et al.
NATURE MEDICINE (2021)
A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells
Xue Chen et al.
ELIFE (2021)
Arterial stiffness and cardiac dysfunction in Hutchinson-Gilford Progeria Syndrome corrected by inhibition of lysyl oxidase
Ryan von Kleeck et al.
LIFE SCIENCE ALLIANCE (2021)
Molecular and Cellular Mechanisms Driving Cardiovascular Disease in Hutchinson-Gilford Progeria Syndrome: Lessons Learned from Animal Models
Ignacio Benedicto et al.
CELLS (2021)
Genetic reduction of mTOR extends lifespan in a mouse model of Hutchinson-Gilford Progeria syndrome
Wayne A. Cabral et al.
AGING CELL (2021)
Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome
Beatriz Marcos-Ramiro et al.
ACS CENTRAL SCIENCE (2021)
Dietary magnesium supplementation improves lifespan in a mouse model of progeria
Ricardo Villa-Bellosta
EMBO MOLECULAR MEDICINE (2020)
Generation of a Hutchinson-Gilford progeria syndrome monkey model by base editing
Fang Wang et al.
PROTEIN & CELL (2020)
Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13
Patricia R. Pitrez et al.
NATURE COMMUNICATIONS (2020)
Therapeutic Antisense Oligonucleotides Are Coming of Age
C. Frank Bennett
ANNUAL REVIEW OF MEDICINE, VOL 70 (2019)
Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells
Magda R. Hamczyk et al.
EMBO MOLECULAR MEDICINE (2019)
Single-dose CRISPR-Cas9 therapy extends lifespan of mice with Hutchinson-Gilford progeria syndrome
Ergin Beyret et al.
NATURE MEDICINE (2019)
Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome
Olaya Santiago-Fernandez et al.
NATURE MEDICINE (2019)
Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome
Beatriz Dorado et al.
CELL DISCOVERY (2019)
Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice
Clea Barcena et al.
NATURE MEDICINE (2019)
ATP-based therapy prevents vascular calcification and extends longevity in a mouse model of Hutchinson-Gilford progeria syndrome
Ricardo Villa-Bellosta
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite
Lara del Campo et al.
AGING CELL (2019)
Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome
Gabriel Balmus et al.
NATURE COMMUNICATIONS (2018)
Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism
Clea Barcena et al.
CELL REPORTS (2018)
Emerging candidate treatment strategies for Hutchinson-Gilford progeria syndrome
Charlotte Strandgren et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2017)
MG132-induced progerin clearance is mediated by autophagy activation and splicing regulation
Karim Harhouri et al.
EMBO MOLECULAR MEDICINE (2017)
Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome
Leslie B. Gordon et al.
CIRCULATION (2016)
Interruption of progerin-lamin A/C binding ameliorates Hutchinson-Gilford progeria syndrome phenotype
Su-Jin Lee et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Modulation of LMNA splicing as a strategy to treat prelamin A diseases
John M. Lee et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Antisense-Based Progerin Downregulation in HGPS-Like Patients' Cells
Karim Harhouri et al.
CELLS (2016)
Impact of Farnesylation Inhibitors on Survival in Hutchinson-Gilford Progeria Syndrome
Leslie B. Gordon et al.
CIRCULATION (2014)
Defective Extracellular Pyrophosphate Metabolism Promotes Vascular Calcification in a Mouse Model of Hutchinson-Gilford Progeria Syndrome That Is Ameliorated on Pyrophosphate Treatment
Ricardo Villa-Bellosta et al.
CIRCULATION (2013)
Targeting Isoprenylcysteine Methylation Ameliorates Disease in a Mouse Model of Progeria
Mohamed X. Ibrahim et al.
SCIENCE (2013)
Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
Fernando G. Osorio et al.
GENES & DEVELOPMENT (2012)
Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome
Leslie B. Gordon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging
Fernando G. Osorio et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging
Ignacio Varela et al.
NATURE MEDICINE (2008)
A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model
Brian C. Capell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation
Shao H. Yang et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Prelamin A and lamin A appear to be dispensable in the nuclear lamina
LG Fong et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome
R Varga et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
P Scaffidi et al.
NATURE MEDICINE (2005)
Lamin A truncation in Hutchinson-Gilford progeria
A De Sandre-Giovannoli et al.
SCIENCE (2003)
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome
M Eriksson et al.
NATURE (2003)