4.5 Article

Tucatinib: an investigational novel therapeutic agent for the treatment of HER-2 colorectal cancer

Related references

Note: Only part of the references are listed.
Article Medicine, General & Internal

Trastuzumab Deruxtecan in HER2-Mutant Non-Small-Cell Lung Cancer

Bob T. Li et al.

Summary: Trastuzumab deruxtecan demonstrated durable anticancer activity in previously treated HER2-mutant NSCLC patients, with two cases of fatal drug-related interstitial lung disease reported. The observed toxic effects were generally consistent with previous studies.

NEW ENGLAND JOURNAL OF MEDICINE (2022)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Oncology

Trastuzumab deruxtecan (DS-8201) in patients with HER2-expressing metastatic colorectal cancer (DESTINY-CRC01): a multicentre, open-label, phase 2 trial

Salvatore Siena et al.

Summary: This study aimed to investigate the antitumour activity and safety of trastuzurnab deruxtecan in patients with HER2-expressing metastatic colorectal cancer. The drug showed promising and durable activity in HER2-positive metastatic colorectal cancer refractory to standard treatment, with a safety profile consistent with previous trials. However, careful monitoring and prompt intervention are required for important risks like interstitial lung disease and pneumonitis.

LANCET ONCOLOGY (2021)

Review Oncology

HER2 as a Predictive Biomarker and Treatment Target in Colorectal Cancer

Astrid De Cuyper et al.

CLINICAL COLORECTAL CANCER (2020)

Article Medicine, General & Internal

Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer

R. K. Murthy et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Oncology

Nationwide trends in incidence, treatment and survival of colorectal cancer patients with synchronous metastases

Lydia G. M. van der Geest et al.

CLINICAL & EXPERIMENTAL METASTASIS (2015)

Article Medicine, General & Internal

Randomized Trial of TAS-102 for Refractory Metastatic Colorectal Cancer

Robert J. Mayer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Review Pharmacology & Pharmacy

Targeting the epidermal growth factor receptor in solid tumors: focus on safety

Eleonora Lucchini et al.

EXPERT OPINION ON DRUG SAFETY (2014)

Article Biochemistry & Molecular Biology

HER-2 overexpression and survival in colorectal cancer: a meta-analysis

Chao Li et al.

JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B (2014)

Article Biotechnology & Applied Microbiology

Expression of HER2 in colorectal cancer does not correlate with prognosis

Wieslaw Janusz Kruszewski et al.

DISEASE MARKERS (2010)

Article Oncology

Lapatinib Side-Effect Management

Cynthia Frankel et al.

CLINICAL JOURNAL OF ONCOLOGY NURSING (2010)

Article Medicine, General & Internal

Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer

Eric Van Cutsem et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)