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ANTIOXIDANTS & REDOX SIGNALING (2011)
The release of high mobility group box 1 in apoptosis is triggered by nucleosomal DNA fragmentation
Yoichiro Yamada et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2011)
Metabolic regulation by HMGB1-mediated autophagy and mitophagy
Rui Kang et al.
AUTOPHAGY (2011)
HMGB1 as an autophagy sensor in oxidative stress
Rui Kang et al.
AUTOPHAGY (2011)
DR396, an apoptotic DNase gamma inhibitor, attenuates high mobility group box 1 release from apoptotic cells
Yoichiro Yamada et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Peroxynitrite induces HMGB1 release by cardiac cells in vitro and HMGB1 upregulation in the infarcted myocardium in vivo
Noureddine Loukili et al.
CARDIOVASCULAR RESEARCH (2011)
High mobility group box 1 induces synoviocyte proliferation in rheumatoid arthritis by activating the signal transducer and activator transcription signal pathway
Hui-Fang Guo et al.
CLINICAL AND EXPERIMENTAL MEDICINE (2011)
Lysosomal thiol reductase negatively regulates autophagy by altering glutathione synthesis and oxidation
Hao-Sen Chiang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Gene Silencing of NALP3 Protects Against Liver Ischemia-Reperfusion Injury in Mice
Ping Zhu et al.
HUMAN GENE THERAPY (2011)
Hemorrhagic Shock Activation of NLRP3 Inflammasome in Lung Endothelial Cells
Meng Xiang et al.
JOURNAL OF IMMUNOLOGY (2011)
Adenovirus Membrane Penetration Activates the NLRP3 Inflammasome
A. U. Barlan et al.
JOURNAL OF VIROLOGY (2011)
Crosstalk in NF-κB signaling pathways
Andrea Oeckinghaus et al.
NATURE IMMUNOLOGY (2011)
Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus
Gina S. Garcia-Romo et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
INTERFERON REGULATORY FACTOR 1 MEDIATES ACETYLATION AND RELEASE OF HIGH MOBILITY GROUP BOX 1 FROM HEPATOCYTES DURING MURINE LIVER ISCHEMIA-REPERFUSION INJURY
Rajeev Dhupar et al.
SHOCK (2011)
Glycyrrhizin Prevents Liver Injury by Inhibition of High-Mobility Group Box 1 Production by Kupffer Cells after Ischemia-Reperfusion in Rats
Masahito Ogiku et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Lipopolysaccharide-induced Notch signaling activation through JNK-dependent pathway regulates inflammatory response
Po-Nien Tsao et al.
JOURNAL OF BIOMEDICAL SCIENCE (2011)
Complement factor 3 deficiency attenuates hemorrhagic shock-related hepatic injury and systemic inflammatory response syndrome
Changchun Cai et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2010)
Antioxidant Inhibits HMGB1 Expression and Reduces Pancreas Injury in Rats with Severe Acute Pancreatitis
Zhong Wei Zhang et al.
DIGESTIVE DISEASES AND SCIENCES (2010)
The Anti-Inflammatory Activity of HMGB1 A Box Is Enhanced When Fused with C-Terminal Acidic Tail
Wei Gong et al.
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2010)
Endogenous HMGB1 regulates autophagy
Daolin Tang et al.
JOURNAL OF CELL BIOLOGY (2010)
Inflammasome-Dependent Release of the Alarmin HMGB1 in Endotoxemia
Mohamed Lamkanfi et al.
JOURNAL OF IMMUNOLOGY (2010)
CARBON MONOXIDE FROM CORM-2 REDUCES HMGB1 RELEASE THROUGH REGULATION OF IFN-β/JAK2/STAT-1/INOS/NO SIGNALING BUT NOT COX-2 IN TLR-ACTIVATED MACROPHAGES
Konstantin Tsoyi et al.
SHOCK (2010)
Legionella pneumophila induces cathepsin B-dependent necrotic cell death with releasing high mobility group box1 in macrophages
Yoshitomo Morinaga et al.
RESPIRATORY RESEARCH (2010)
Quercetin Prevents LPS-Induced High-Mobility Group Box 1 Release and Proinflammatory Function
Daolin Tang et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2009)
High mobility group B2 is secreted by myeloid cells and has mitogenic and chemoattractant activities similar to high mobility group B1
Tobias Pusterla et al.
AUTOIMMUNITY (2009)
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
YoungSik Cho et al.
CELL (2009)
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
Sudan He et al.
CELL (2009)
NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways
Stephen B. Willingham et al.
JOURNAL OF IMMUNOLOGY (2009)
HMGB1 Is Phosphorylated by Classical Protein Kinase C and Is Secreted by a Calcium-Dependent Mechanism
Young Joo Oh et al.
JOURNAL OF IMMUNOLOGY (2009)
Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis
Shaival H. Dave et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
The Free Radical Scavenger Edaravone Rescues Rats from Cerebral Infarction by Attenuating the Release of High-Mobility Group Box-1 in Neuronal Cells
Kiyoshi Kikuchi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells
Robin R. Craven et al.
PLOS ONE (2009)
EDARAVONE, A NOVEL FREE RADICAL SCAVENGER, REDUCES HIGH-MOBILITY GROUP BOX 1 AND PROLONGS SURVIVAL IN A NEONATAL SEPSIS MODEL
Shin Kato et al.
SHOCK (2009)
Amino acid residues 201-205 in C-terminal acidic tail region plays a crucial role in antibacterial activity of HMGB1
Wei Gong et al.
JOURNAL OF BIOMEDICAL SCIENCE (2009)
CRM1-Mediated Nuclear Export of Proteins and Drug Resistance in Cancer
Joel G. Turner et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Poly ADP-ribose polymerase-1: An international molecule of mystery
Bethany C. Woodhouse et al.
DNA REPAIR (2008)
Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation
Masakazu Okamoto et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Calcium/calmodulin-dependent protein kinase (CaMK) IV mediates nucleocytoplasmic shuttling and release of HMGB1 during lipopolysaccharide stimulation of macrophages
Xianghong Zhang et al.
JOURNAL OF IMMUNOLOGY (2008)
The Notch pathway in podocytes plays a role in the development of glomerular disease
Thiruvur Niranjan et al.
NATURE MEDICINE (2008)
HMGB1 release induced by liver ischemia involves Toll-like receptor 4-dependent reactive oxygen species production and calcium-mediated signaling
Allan Tsung et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Innate immune recognition triggers secretion of lysosomal enzymes by macrophages
Rebecca L. Lackman et al.
TRAFFIC (2007)
The anti-inflammatory effects of heat shock protein 72 involve inhibition of high-mobility-group box 1 release and proinflammatory function in macrophages
Daolin Tang et al.
JOURNAL OF IMMUNOLOGY (2007)
Hemorrhagic shock induces NAD(P)H oxidase activation in neutrophils: Role of HMGB1-TLR4 signaling
Jie Fan et al.
JOURNAL OF IMMUNOLOGY (2007)
Role of oxidative stress in alterations of mitochondrial function in ischemic-reperfused hearts
Zhanna Makazan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1
Daolin Tang et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Distribution and cellular localization of high mobility group box protein 1 (HMGB1) in the spinal cord of a transgenic mouse model of ALS
Daniele Lo Coco et al.
NEUROSCIENCE LETTERS (2007)
Cytolytic cells induce HMGB1 release from melanoma cell lines
Norimasa Ito et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
The JAK-STAT signaling pathway: Input and output intergration
Peter J. Murray
JOURNAL OF IMMUNOLOGY (2007)
Exposure of the promonocytic cell line THP-1 to Escherichia coli induces IFN-γ-Inducible lysosomal thiol reductase expression by inflammatory cytokines
Rebecca L. Lackman et al.
JOURNAL OF IMMUNOLOGY (2006)
Role of HMGB1 in apoptosis-mediated sepsis lethality
Shixin Qin et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
Nitric oxide down-regulates caveolin-1 expression in rat brains during focal cerebral ischemia and reperfusion injury
JG Shen et al.
JOURNAL OF NEUROCHEMISTRY (2006)
NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1
C Semino et al.
BLOOD (2005)
Poly(ADP-Ribose) polymerases:: Homology, structural domains and functions.: Novel therapeutical applications
PA Nguewa et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2005)
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
P Jagtap et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Phospholipase C gamma 1 is required for activation of store-operated channels in human keratinocytes
CL Tu et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2005)
Amphoterin as an extracellular regulator of cell motility: from discovery to disease
HJ Huttunen et al.
JOURNAL OF INTERNAL MEDICINE (2004)
Cutting edge:: Direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-κB
HS Park et al.
JOURNAL OF IMMUNOLOGY (2004)
Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms
GQ Chen et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion
T Bonaldi et al.
EMBO JOURNAL (2003)
20 years of Ins(1,4,5)P3, and 40 years before
RF Irvine
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Increased susceptibility to LPS-induced endotoxin shock in secretory leukoprotease inhibitor (SLPI)-deficient mice
A Nakamura et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Structural basis for the proinflammatory cytokine activity of high mobility group box 1
JH Li et al.
MOLECULAR MEDICINE (2003)
Degradation of chromosomal DNA during apoptosis
S Nagata et al.
CELL DEATH AND DIFFERENTIATION (2003)
The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway
S Gardella et al.
EMBO REPORTS (2002)
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
P Scaffidi et al.
NATURE (2002)
Secretory lysosomes
EJ Blott et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
HMG 1 and 2: architectural DNA-binding proteins
JO Thomas
BIOCHEMICAL SOCIETY TRANSACTIONS (2001)
Immune depression in polymicrobial sepsis: The role of necrotic (injured) tissue and endotoxin
A Ayala et al.
CRITICAL CARE MEDICINE (2000)