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A review on wound dressings: Antimicrobial agents, biomaterials, fabrication techniques, and stimuli-responsive drug release

Journal

EUROPEAN POLYMER JOURNAL
Volume 173, Issue -, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.eurpolymj.2022.111293

Keywords

Wound dressing; Biomaterials; Fabrication techniques; 3D printing; Stimuli-responsive wound dressing

Funding

  1. NSERC Discovery [537244-2018]
  2. CFI John R. Evans Leader Fund [37696]

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Skin, the largest organ of the body, protects against injuries and is prone to wounds. Wound care is critical for compromised immune systems or severe wounds. Infection is a common complication, and wound dressings are widely used to aid in complete skin recovery. Recent research focuses on antimicrobial agents, biomaterials, and fabrication techniques in wound dressings, emphasizing the importance of non-toxic solvents and stimuli-responsive dressings.
Skin, the largest organ of the body, protects the inner organs against the ambient environment, and it is prone to internal and external injuries in the form of wounds. The wound healing process of the body can be hindered by a compromised immune system or severity of the wound, making wound care critical under these circumstances. Infection is the most prevalent complication that arises in wounds, and wound dressings are widely used to assist the self-healing process of the body for complete skin recovery. In this review, the recently developed wound dressings are reviewed, focusing on reviewing various antimicrobial agents, biomaterials, and fabrication techniques. In moving toward green chemistry, the importance of using non-toxic solvents for fabricating wound dressing is emphasized. Finally, the importance of using stimuli-responsive wound dressings as a recent trend in wound dressing is highlighted. The outcome of this review will lead to novel research in the field of wound dressing and drug-eluting constructs.

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