Dual Photocatalysis for the Straightforward Coupling of Thiosugars and Arylsulfoximines: Towards Unprecedented Cyclic Heteroatomic Structures

A general, scalable and easy to implement protocol is described for the coupling of thiosugars and various ortho-functionalized S-aryl S-perfluoroalkyl sulfoximines. This dual photocatalysis methodology was developed with a commercial hydrogen atom transfer reagent and produced key structures that were transformed into original cyclic skeletons bearing previously undescribed chemical functions.

Automated summary

This study presents a general, scalable, and easy to implement protocol for synthesizing thiosugars and various ortho-functionalized compounds. The dual photocatalysis methodology using a commercial hydrogen atom transfer reagent resulted in the production of key structures, which were then transformed into original cyclic skeletons bearing previously undescribed chemical functions.