4.7 Article

Fibrin-targeting molecular MRI in inflammatory CNS disorders

Related references

Note: Only part of the references are listed.
Review Clinical Neurology

The extracellular matrix as modifier of neuroinflammation and remyelination in multiple sclerosis

Samira Ghorbani et al.

Summary: Failure of remyelination in multiple sclerosis lesions is influenced by changes in extracellular matrix components, which not only impair oligodendrocyte recruitment but also enhance inflammatory responses. The deposition of matrix members is mainly due to cells such as reactive astrocytes and microglia/macrophages, leading to both pro-inflammatory and anti-inflammatory effects within the lesions.

BRAIN (2021)

Review Neurosciences

Molecular MRI of Neuroinflammation: Time to Overcome the Translational Roadblock

Maxime Gauberti et al.

Summary: The use of magnetic resonance imaging (MRI) to detect molecular targets in the central nervous system non-invasively has drawn interest for many years. Recent advances in using large superparamagnetic probes like micro-sized particles of iron oxide (MPIO) have significantly improved the sensitivity of molecular MRI in neuroinflammation studies.

NEUROSCIENCE (2021)

Article Radiology, Nuclear Medicine & Medical Imaging

Molecular Magnetic Resonance Imaging of Fibrin Deposition in the Liver as an Indicator of Tissue Injury and Inflammation

Iliyana Atanasova et al.

INVESTIGATIVE RADIOLOGY (2020)

Review Nanoscience & Nanotechnology

Molecular imaging of extracellular matrix proteins with targeted probes using magnetic resonance imaging

Mani Salarian et al.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2020)

Article Clinical Neurology

MS optic neuritis-induced long-term structural changes within the visual pathway

Marc Pawlitzki et al.

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2020)

Article Multidisciplinary Sciences

Cerebral amyloid angiopathy-linked β-amyloid mutations promote cerebral fibrin deposits via increased binding affinity for fibrinogen

Steven A. Cajamarca et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

atlasBREX: Automated template-derived brain extraction in animal MRI

Johannes Lohmeier et al.

SCIENTIFIC REPORTS (2019)

Article Clinical Neurology

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria

Alan J. Thompson et al.

LANCET NEUROLOGY (2018)

Review Neurosciences

Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics

Mark A. Petersen et al.

NATURE REVIEWS NEUROSCIENCE (2018)

Review Clinical Neurology

A Review of the Current Evidence on Gadolinium Deposition in the Brain

Richard Pullicino et al.

CLINICAL NEURORADIOLOGY (2018)

Article Clinical Neurology

Meningeal inflammation and cortical demyelination in acute multiple sclerosis

Ryan J. Bevan et al.

ANNALS OF NEUROLOGY (2018)

Article Medicine, General & Internal

Multiple sclerosis

Massimo Filippi et al.

NATURE REVIEWS DISEASE PRIMERS (2018)

Article Neurosciences

Molecular and Metabolic Imaging in Multiple Sclerosis

Marcello Moccia et al.

NEUROIMAGING CLINICS OF NORTH AMERICA (2017)

Article Clinical Neurology

Fibrin(ogen) and Neurodegeneration in the Progressive Multiple Sclerosis Cortex

Richard L. Yates et al.

ANNALS OF NEUROLOGY (2017)

Article Medicine, Research & Experimental

Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis

Barry S. Shea et al.

JCI INSIGHT (2017)

Article Chemistry, Multidisciplinary

A Manganese Alternative to Gadolinium for MRI Contrast

Eric M. Gale et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Review Clinical Neurology

Nonconventional MRI and microstructural cerebral changes in multiple sclerosis

Christian Enzinger et al.

NATURE REVIEWS NEUROLOGY (2015)

Article Chemistry, Multidisciplinary

Activation and Retention: A Magnetic Resonance Probe for the Detection of Acute Thrombosis

Galen S. Loving et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Clinical Neurology

Gray matter damage predicts the accumulation of disability 13 years later in MS

Massimo Filippi et al.

NEUROLOGY (2013)

Review Pharmacology & Pharmacy

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

Cris S. Constantinescu et al.

BRITISH JOURNAL OF PHARMACOLOGY (2011)

Article Computer Science, Interdisciplinary Applications

N4ITK: Improved N3 Bias Correction

Nicholas J. Tustison et al.

IEEE TRANSACTIONS ON MEDICAL IMAGING (2010)

Article Radiology, Nuclear Medicine & Medical Imaging

Thrombus Imaging With Fibrin-Specific Gadolinium-Based MR Contrast Agent EP-2104R Results of a Phase II Clinical Study of Feasibility

Josef Vymazal et al.

INVESTIGATIVE RADIOLOGY (2009)

Article Chemistry, Multidisciplinary

EP-2104R: A fibrin-specific gadolinium-based MRI contrast agent for detection of thrombus

Kirsten Overoye-Chan et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

Article Multidisciplinary Sciences

Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets

May H. Han et al.

NATURE (2008)

Article Clinical Neurology

The clinico-radiological paradox in multiple sclerosis revisited

F Barkhof

CURRENT OPINION IN NEUROLOGY (2002)