'Obesities': Position statement on a complex disease entity with multifaceted drivers

Academic medicine fosters research that moves from discovery to translation, at the same time as promoting education of the next generation of professionals. In the field of obesity, the supposed integration of knowledge, discovery and translation research to clinical care is being particularly hampered. The classification of obesity based on the body mass index does not account for several subtypes of obesity. The lack of a universally shared definition of obesities makes it impossible to establish the real burden of the different obesity phenotypes. The individual's genotype, adipotype, enterotype and microbiota interplays with macronutrient intake, appetite, metabolism and thermogenesis. Further investigations based on the concept of differently diagnosed obesities are required.

Automated summary

Academic medicine aims to promote research that moves from discovery to translation and educate the next generation of professionals. However, in the field of obesity, integration of knowledge and translation research is hindered by the inability of the body mass index classification to account for multiple subtypes of obesity, and the lack of a universally shared definition, which prevents the determination of the true burden of different obesity phenotypes.