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The biology and function of exosomes in cancer
Raghu Kalluri
JOURNAL OF CLINICAL INVESTIGATION (2016)
Donor dendritic cell-derived exosomes promote allograft-targeting immune response
Quan Liu et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Exosomes as therapeutics: The implications of molecular composition and exosomal heterogeneity
Scott W. Ferguson et al.
JOURNAL OF CONTROLLED RELEASE (2016)
Microvesicles and exosomes: new players in metabolic and cardiovascular disease
Charlotte Lawson et al.
JOURNAL OF ENDOCRINOLOGY (2016)
Extracellular Vesicles Exploit Viral Entry Routes for Cargo Delivery
Helena M. van Dongen et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2016)
The potential of endurance exercise-derived exosomes to treat metabolic diseases
Adeel Safdar et al.
NATURE REVIEWS ENDOCRINOLOGY (2016)
Endothelial Microparticle-Derived Reactive Oxygen Species: Role in Endothelial Signaling and Vascular Function
Dylan Burger et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
Joanna Kowal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Adipocyte-derived microvesicles from obese mice induce M1 macrophage phenotype through secreted miR-155
Yaqin Zhang et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2016)
Extracellular vesicles secreted by highly metastatic clonal variants of osteosarcoma preferentially localize to the lungs and induce metastatic behaviour in poorly metastatic clones
Rebecca Macklin et al.
ONCOTARGET (2016)
The RNA-Binding Protein SYNCRIP Is a Component of the Hepatocyte Exosomal Machinery Controlling MicroRNA Sorting
Laura Santangelo et al.
CELL REPORTS (2016)
Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction
Matthew J. Shurtleff et al.
ELIFE (2016)
Circulating microRNAs are deregulated in overweight/obese children: preliminary results of the I.Family study
Giuseppe Iacomino et al.
GENES AND NUTRITION (2016)
Coronary Artery-Bypass-Graft Surgery Increases the Plasma Concentration of Exosomes Carrying a Cargo of Cardiac MicroRNAs: An Example of Exosome Trafficking Out of the Human Heart with Potential for Cardiac Biomarker Discovery
Costanza Emanueli et al.
PLOS ONE (2016)
Cells release subpopulations of exosomes with distinct molecular and biological properties
Eduard Willms et al.
SCIENTIFIC REPORTS (2016)
The investigation of circulating microRNAs associated with lipid metabolism in childhood obesity
U. Can et al.
PEDIATRIC OBESITY (2016)
MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA
Ruenn Chai Lai et al.
JOURNAL OF EXTRACELLULAR VESICLES (2016)
High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources
Reka A. Haraszti et al.
JOURNAL OF EXTRACELLULAR VESICLES (2016)
Exosomes in Tears of Healthy Individuals: Isolation, Identification, and Characterization
A. E. Grigor'eva et al.
BIOCHEMISTRY MOSCOW-SUPPLEMENT SERIES B-BIOMEDICAL CHEMISTRY (2016)
Weight-reduction through a low-fat diet causes differential expression of circulating microRNAs in obese C57BL/6 mice
Ching-Hua Hsieh et al.
BMC GENOMICS (2015)
Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells
Claudiane Guay et al.
CELL COMMUNICATION AND SIGNALING (2015)
Circulating Exosomes Induced by Cardiac Pressure Overload Contain Functional Angiotensin II Type 1 Receptors
Gianluigi Pironti et al.
CIRCULATION (2015)
Excess Metabolic and Cardiovascular Risk is not Manifested in all Phenotypes of Polycystic Ovary Syndrome: Implications for Diagnosis and Treatment
Georgios Daskalopoulos et al.
CURRENT VASCULAR PHARMACOLOGY (2015)
Metabolic phenotype-microRNA data fusion analysis of the systemic consequences of Roux-en-Y gastric bypass surgery
Q. Wu et al.
INTERNATIONAL JOURNAL OF OBESITY (2015)
Stabilization of Exosome-targeting Peptides via Engineered Glycosylation
Michelle E. Hung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
The Effect of Glucose on the Release and Bioactivity of Exosomes From First Trimester Trophoblast Cells
Gregory E. Rice et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2015)
Mass-Spectrometry-Based Molecular Characterization of Extracellular Vesicles: Lipidomics and Proteomics
Simion Kreimer et al.
JOURNAL OF PROTEOME RESEARCH (2015)
Driving the Hypoxia-Inducible Pathway in Human Pericytes Promotes Vascular Density in an Exosome-Dependent Manner
Jamie N. Mayo et al.
MICROCIRCULATION (2015)
Tumour exosome integrins determine organotropic metastasis
Ayuko Hoshino et al.
NATURE (2015)
Exosomes in bodily fluids are a highly stable resource of disease biomarkers
Stephanie Boukouris et al.
PROTEOMICS CLINICAL APPLICATIONS (2015)
Ectosomes and exosomes: shedding the confusion between extracellular vesicles
Emanuele Cocucci et al.
TRENDS IN CELL BIOLOGY (2015)
Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters
Charles P. Lai et al.
NATURE COMMUNICATIONS (2015)
Directional cell movement through tissues is controlled by exosome secretion
Bong Hwan Sung et al.
NATURE COMMUNICATIONS (2015)
Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles
Valentina R. Minciacchi et al.
ONCOTARGET (2015)
Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration
Liang Ma et al.
CELL RESEARCH (2015)
Migrasomes: a new organelle of migrating cells
Bruno da Rocha-Azevedo et al.
CELL RESEARCH (2015)
Classification and Diagnosis of Diabetes
[Anonymous]
DIABETES CARE (2015)
N-linked (N-) Glycoproteomics of Urimary Exosomes
Mayank Saraswat et al.
MOLECULAR & CELLULAR PROTEOMICS (2015)
Adipocyte-derived exosomal miRNAs: a novel mechanism for obesity-related disease
Sarah C. Ferrante et al.
PEDIATRIC RESEARCH (2015)
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
Oscar P. B. Wiklander et al.
JOURNAL OF EXTRACELLULAR VESICLES (2015)
Biological properties of extracellular vesicles and their physiological functions
Maria Yanez-Mo et al.
JOURNAL OF EXTRACELLULAR VESICLES (2015)
Elevated circulating microRNA-122 is associated with obesity and insulin resistance in young adults
Rui Wang et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2015)
Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter
Charles P. Lai et al.
ACS NANO (2014)
Exosomes from breast milk inhibit HIV-1 infection of dendritic cells and subsequent viral transfer to CD4+ T cells
Tanja I. Naslund et al.
AIDS (2014)
Long Noncoding RNAs in Patients With Acute Myocardial Infarction
Melanie Vausort et al.
CIRCULATION RESEARCH (2014)
Biogenesis and secretion of exosomes
Joanna Kowal et al.
CURRENT OPINION IN CELL BIOLOGY (2014)
Differential Expression of MicroRNAs in Omental Adipose Tissue From Gestational Diabetes Mellitus Subjects Reveals miR-222 as a Regulator of ERα Expression in Estrogen-Induced Insulin Resistance
Zhonghua Shi et al.
ENDOCRINOLOGY (2014)
Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study
Nicolas Amabile et al.
EUROPEAN HEART JOURNAL (2014)
Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles
G. R. Willis et al.
HUMAN REPRODUCTION (2014)
Mass Spectrometry Methodology in Lipid Analysis
Lin Li et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Application of microRNAs in diabetes mellitus
Haiyong Chen et al.
JOURNAL OF ENDOCRINOLOGY (2014)
Extracellular vesicles from blood plasma: determination of their morphology, size, phenotype and concentration
N. Arraud et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2014)
Heparan sulfate proteoglycan as a cell-surface endocytosis receptor
Helena C. Christianson et al.
MATRIX BIOLOGY (2014)
Human Adipocyte Extracellular Vesicles in Reciprocal Signaling Between Adipocytes and Macrophages
Mariette E. G. Kranendonk et al.
OBESITY (2014)
Effect of Extracellular Vesicles of Human Adipose Tissue on Insulin Signaling in Liver and Muscle Cells
Mariette E. G. Kranendonk et al.
OBESITY (2014)
Quantitative and stoichiometric analysis of the microRNA content of exosomes
John R. Chevillet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Harnessing the exosome-induced immune response for cancer immunotherapy
Ulf Gehrmann et al.
SEMINARS IN CANCER BIOLOGY (2014)
Hrs- and CD63-Dependent Competing Mechanisms Make Different Sized Endosomal Intraluminal Vesicles
James R. Edgar et al.
TRAFFIC (2014)
MicroRNA Expression in Circulating Microvesicles Predicts Cardiovascular Events in Patients With Coronary Artery Disease
Felix Jansen et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2014)
Co-isolation of extracellular vesicles and high-density lipoproteins using density gradient ultracentrifugation
Yuana Yuana et al.
JOURNAL OF EXTRACELLULAR VESICLES (2014)
Routes and mechanisms of extracellular vesicle uptake
Laura Ann Mulcahy et al.
JOURNAL OF EXTRACELLULAR VESICLES (2014)
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood
Lesley Cheng et al.
JOURNAL OF EXTRACELLULAR VESICLES (2014)
Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
Alicia Llorente et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2013)
Multicolor Flow Cytometry and Nanoparticle Tracking Analysis of Extracellular Vesicles in the Plasma of Normal Pregnant and Pre-eclamptic Women
Rebecca A. Dragovic et al.
BIOLOGY OF REPRODUCTION (2013)
Targeting the Circulating MicroRNA Signature of Obesity
Francisco Jose Ortega et al.
CLINICAL CHEMISTRY (2013)
Insulinoma-released exosomes activate autoreactive marginal zone-like B cells that expand endogenously in prediabetic NOD mice
Roman Bashratyan et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Visualization and in vivo tracking of the exosomes of murine melanoma B16-BL6 cells in mice after intravenous injection
Yuki Takahashi et al.
JOURNAL OF BIOTECHNOLOGY (2013)
Exosomes in tumor microenvironment influence cancer progression and metastasis
Christoph Kahlert et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2013)
Microparticle Increase in Severe Obesity: Not Related to Metabolic Syndrome and Unchanged after Massive Weight Loss
Alain Stepanian et al.
OBESITY (2013)
Sonic Hedgehog Carried by Microparticles Corrects Angiotensin II-Induced Hypertension and Endothelial Dysfunction in Mice
Vannina Gonzalez Marrachelli et al.
PLOS ONE (2013)
Exosomal Signaling during Hypoxia Mediates Microvascular Endothelial Cell Migration and Vasculogenesis
Carlos Salomon et al.
PLOS ONE (2013)
Serum Circulating microRNA Profiling for Identification of Potential Type 2 Diabetes and Obesity Biomarkers
Nuria Pescador et al.
PLOS ONE (2013)
Hypoxia-Induced Changes in the Bioactivity of Cytotrophoblast-Derived Exosomes
Carlos Salomon et al.
PLOS ONE (2013)
Cancer cell exosomes depend on cell-surface heparan sulfate proteoglycans for their internalization and functional activity
Helena C. Christianson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development
Paulina Kucharzewska et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Proteomics, transcriptomics and lipidomics of exosomes and ectosomes
Dong-Sic Choi et al.
PROTEOMICS (2013)
Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells
Jun Suzuki et al.
SCIENCE (2013)
Restoration of glycemic control in patients with type 2 diabetes mellitus after bariatric surgery is associated with reduction in microparticles
Vicky Cheng et al.
SURGERY FOR OBESITY AND RELATED DISEASES (2013)
Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs
Carolina Villarroya-Beltri et al.
NATURE COMMUNICATIONS (2013)
Circulating Microparticles Carry a Functional Endothelial Nitric Oxide Synthase That Is Decreased in Patients With Endothelial Dysfunction
Patrick Horn et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)
Regulation of lipid signaling by diacylglycerol kinases during T cell development and function
Sruti Krishna et al.
FRONTIERS IN IMMUNOLOGY (2013)
Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes
Rossella Crescitelli et al.
JOURNAL OF EXTRACELLULAR VESICLES (2013)
Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease
Dolores Di Vizio et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Hypoxic enhancement of exosome release by breast cancer cells
Hamish W. King et al.
BMC CANCER (2012)
Plasma Endothelial Microparticles and Their Correlation With the Presence of Hypertension and Arterial Stiffness in Patients With Type 2 Diabetes
Yinghua Chen et al.
JOURNAL OF CLINICAL HYPERTENSION (2012)
Prospective Study on Circulating MicroRNAs and Risk of Myocardial Infarction
Anna Zampetaki et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2012)
Characterization of Membrane-shed Microvesicles from Cytokine-stimulated β-Cells Using Proteomics Strategies
Giuseppe Palmisano et al.
MOLECULAR & CELLULAR PROTEOMICS (2012)
Exosomal cell-to-cell transmission of alpha synuclein oligomers
Karin M. Danzer et al.
MOLECULAR NEURODEGENERATION (2012)
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs
Eduard Hergenreider et al.
NATURE CELL BIOLOGY (2012)
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
Hector Peinado et al.
NATURE MEDICINE (2012)
Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry
Els J. van der Vlist et al.
NATURE PROTOCOLS (2012)
MicroRNAs in metabolism and metabolic disorders
Veerle Rottiers et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein
Joseph F. Nabhan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation
Hina Kalra et al.
PLOS BIOLOGY (2012)
RNA-containing exosomes in human nasal secretions
Cecilia Lasser et al.
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY (2011)
Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy
Viktoriya Sokolova et al.
COLLOIDS AND SURFACES B-BIOINTERFACES (2011)
Protein Targeting to Exosomes/Microvesicles by Plasma Membrane Anchors
Beiyi Shen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Insulinoma-Released Exosomes or Microparticles Are Immunostimulatory and Can Activate Autoreactive T Cells Spontaneously Developed in Nonobese Diabetic Mice
Huiming Sheng et al.
JOURNAL OF IMMUNOLOGY (2011)
Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages
Cecilia Lasser et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis
Rebecca A. Dragovic et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2011)
MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
Kasey C. Vickers et al.
NATURE CELL BIOLOGY (2011)
Under pressure: the search for the essential mechanisms of hypertension
Thomas M. Coffman
NATURE MEDICINE (2011)
Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
Jason D. Arroyo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Alterations in Platelet Function and Cell-Derived Microvesicles in Recently Menopausal Women: Relationship to Metabolic Syndrome and Atherogenic Risk
Muthuvel Jayachandran et al.
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH (2011)
Circulating level of microparticles and their correlation with arterial elasticity and endothelium-dependent dilation in patients with type 2 diabetes mellitus
Bo Feng et al.
ATHEROSCLEROSIS (2010)
Circulating MicroRNAs in Patients With Coronary Artery Disease
Stephan Fichtlscherer et al.
CIRCULATION RESEARCH (2010)
Circulating microRNAs are new and sensitive biomarkers of myocardial infarction
Yuri D'Alessandra et al.
EUROPEAN HEART JOURNAL (2010)
Increased circulating CD31+/annexin V+ apoptotic microparticles and decreased circulating endothelial progenitor cell levels in hypertensive patients with microalbuminuria
Po-Hsun Huang et al.
JOURNAL OF HYPERTENSION (2010)
Lipidomics: coming to grips with lipid diversity
Andrej Shevchenko et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Oncosome Formation in Prostate Cancer: Association with a Region of Frequent Chromosomal Deletion in Metastatic Disease
Dolores Di Vizio et al.
CANCER RESEARCH (2009)
Adipose Tissue Exosome-Like Vesicles Mediate Activation of Macrophage-Induced Insulin Resistance
Zhong-bin Deng et al.
DIABETES (2009)
Lipophilic Dye Staining of Cryptococcus neoformans Extracellular Vesicles and Capsule
Andre Moraes Nicola et al.
EUKARYOTIC CELL (2009)
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
Sekar Kathiresan et al.
NATURE GENETICS (2009)
ExoCarta: A compendium of exosomal proteins and RNA
Suresh Mathivanan et al.
PROTEOMICS (2009)
Intercellular transfer of the oncogenic receptor EGFrvIII by microvesicles derived from tumour cells
Khalid Al-Nedawi et al.
NATURE CELL BIOLOGY (2008)
Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
Johan Skog et al.
NATURE CELL BIOLOGY (2008)
Cathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles
Ilaria Giusti et al.
NEOPLASIA (2008)
Role of the T cell in the genesis of angiotensin II-induced hypertension and vascular dysfunction
Tomasz J. Guzik et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Exosome lipidomics unravels lipid sorting at the level of multivesicular bodies
Caroline Subra et al.
BIOCHIMIE (2007)
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
Carey N. Lumeng et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Mature dendritic cells pulsed with exosomes stimulate efficient cytotoxic T-lymphocyte responses and antitumour immunity
Siguo Hao et al.
IMMUNOLOGY (2007)
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
Hadi Valadi et al.
NATURE CELL BIOLOGY (2007)
A comprehensive classification system for lipids
E Fahy et al.
JOURNAL OF LIPID RESEARCH (2005)
Shed membrane particles from T lymphocytes impair endothelial function and regulate endothelial protein expression
S Martin et al.
CIRCULATION (2004)
Role of platelet microparticles in the production of thromboxane by rabbit pulmonary artery
SL Pfister
HYPERTENSION (2004)
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
HY Xu et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Tumor-derived exosomes:: a new source of tumor rejection antigens
F André et al.
VACCINE (2002)
Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus
M Diamant et al.
CIRCULATION (2002)
Changes in phospholipid extractability and composition accompany mineralization of chicken growth plate cartilage matrix vesicles
LNY Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Proteomic analysis of dendritic cell-derived exosomes:: A secreted subcellular compartment distinct from apoptotic vesicles
C Théry et al.
JOURNAL OF IMMUNOLOGY (2001)