Related references
Note: Only part of the references are listed.Human UPF3A and UPF3B enable fault-tolerant activation of nonsense-mediated mRNA decay
Damaris Wallmeroth et al.
EMBO JOURNAL (2022)
The Branched Nature of the Nonsense-Mediated mRNA Decay Pathway
Zhongxia Yi et al.
TRENDS IN GENETICS (2021)
Twelve years of SAMtools and BCFtools
Petr Danecek et al.
GIGASCIENCE (2021)
Translational repression of NMD targets by GIGYF2 and EIF4E2
Boris Zinshteyn et al.
PLOS GENETICS (2021)
Chemical crosslinking enhances RNA immunoprecipitation for efficient identification of binding sites of proteins that photo-crosslink poorly with RNA
Robert D. Patton et al.
RNA (2020)
A synonymous UPF3B variant causing a speech disorder implicates NMD as a regulator of neurodevelopmental disorder gene networks
Deepti Domingo et al.
HUMAN MOLECULAR GENETICS (2020)
The role of the NMD factor UPF3B in olfactory sensory neurons
Kun Tan et al.
ELIFE (2020)
CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex
Jennifer Gerbracht et al.
NUCLEIC ACIDS RESEARCH (2020)
Nonsense-Mediated mRNA Decay Begins Where Translation Ends
Evangelos D. Karousis et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2019)
PTC-bearing mRNA elicits a genetic compensation response via Upf3a and COMPASS components
Zhipeng Ma et al.
NATURE (2019)
Quality and quantity control of gene expression by nonsense-mediated mRNA decay
Tatsuaki Kurosaki et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Nonsense-mediated mRNA decay: The challenge of telling right from wrong in a complex transcriptome
Aparna Kishor et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2019)
A Upf3b-mutant mouse model with behavioral and neurogenesis defects
L. Huang et al.
MOLECULAR PSYCHIATRY (2018)
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay
Thomas D. Baird et al.
ELIFE (2018)
The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity
Justin W. Mabin et al.
CELL REPORTS (2018)
A GC-rich sequence feature in the 3′ UTR directs UPF1-dependent mRNA decay in mammalian cells
Naoto Imamachi et al.
GENOME RESEARCH (2017)
Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6-and SMG7-mediated degradation pathways
Martino Colombo et al.
RNA (2017)
The exon junction complex: a lifelong guardian of mRNA fate
Lauren A. Woodward et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2017)
UMI-tools: modeling sequencing errors in Unique Molecular Identifiers to improve quantification accuracy
Tom Smith et al.
GENOME RESEARCH (2017)
High-resolution profiling of NMD targets in yeast reveals translational fidelity as a basis for substrate selection
Alper Celik et al.
RNA (2017)
Dual function of UPF3B in early and late translation termination
Gabriele Neu-Yilik et al.
EMBO JOURNAL (2017)
The exon junction complex as a node of post-transcriptional networks
Herve Le Hir et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay
Eleen Y. Shum et al.
CELL (2016)
Near-optimal probabilistic RNA-seq quantification
Nicolas L. Bray et al.
NATURE BIOTECHNOLOGY (2016)
Exon Junction Complexes: Supervising the Gene Expression Assembly Line
Volker Boehm et al.
TRENDS IN GENETICS (2016)
Rapid Protein Depletion in Human Cells by Auxin-Inducible Degron Tagging with Short Homology Donors
Toyoaki Natsume et al.
CELL REPORTS (2016)
Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story
Feng He et al.
ANNUAL REVIEW OF GENETICS, VOL 49 (2015)
The unfolded protein response is shaped by the NMD pathway
Rachid Karam et al.
EMBO REPORTS (2015)
Full UPF3B function is critical for neuronal differentiation of neural stem cells
Tahani Alrahbeni et al.
MOLECULAR BRAIN (2015)
A post-translational regulatory switch on UPF1 controls targeted mRNA degradation
Tatsuaki Kurosaki et al.
GENES & DEVELOPMENT (2014)
Normalization of RNA-seq data using factor analysis of control genes or samples
Davide Risso et al.
NATURE BIOTECHNOLOGY (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
STAR: ultrafast universal RNA-seq aligner
Alexander Dobin et al.
BIOINFORMATICS (2013)
Exome sequencing identifies UPF3B as the causative gene for a Chinese non-syndrome mental retardation pedigree
X. Xu et al.
CLINICAL GENETICS (2013)
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran et al.
NATURE PROTOCOLS (2013)
The Cellular EJC Interactome Reveals Higher-Order mRNP Structure and an EJC-SR Protein Nexus
Guramrit Singh et al.
CELL (2012)
Broadening the phenotype associated with mutations in UPF3B: Two further cases with renal dysplasia and variable developmental delay
Sally Ann Lynch et al.
EUROPEAN JOURNAL OF MEDICAL GENETICS (2012)
Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability
L. S. Nguyen et al.
MOLECULAR PSYCHIATRY (2012)
The cryo-EM structure of the UPF-EJC complex shows UPF1 poised toward the RNA 3′ end
Roberto Melero et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
Interaction of PABPC1 with the translation initiation complex is critical to the NMD resistance of AUG-proximal nonsense mutations
Isabel Peixeiro et al.
NUCLEIC ACIDS RESEARCH (2012)
Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability
Hidenori Tani et al.
RNA BIOLOGY (2012)
RNA Homeostasis Governed by Cell Type-Specific and Branched Feedback Loops Acting on NMD
Lulu Huang et al.
MOLECULAR CELL (2011)
Identification of a MicroRNA that Activates Gene Expression by Repressing Nonsense-Mediated RNA Decay
Ivone G. Bruno et al.
MOLECULAR CELL (2011)
A novel frameshift mutation in UPF3B identified in brothers affected with childhood onset schizophrenia and autism spectrum disorders
A. M. Addington et al.
MOLECULAR PSYCHIATRY (2011)
A hyperactive piggyBac transposase for mammalian applications
Kosuke Yusa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Drosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent manner
Paul Avery et al.
RNA (2011)
Autoregulation of the nonsense-mediated mRNA decay pathway in human cells
Hasmik Yepiskoposyan et al.
RNA (2011)
Upf1 Senses 3′UTR Length to Potentiate mRNA Decay
J. Robert Hogg et al.
CELL (2010)
Mutations of the UPF3B gene, which encodes a protein widely expressed in neurons, are associated with nonspecific mental retardation with or without autism
F. Laumonnier et al.
MOLECULAR PSYCHIATRY (2010)
Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex.
Gretel Buchwald et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
A UPF3-mediated regulatory switch that maintains RNA surveillance
Wai-Kin Chan et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways
Pavel V. Ivanov et al.
EMBO JOURNAL (2008)
NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements
Joachim Weischenfeldt et al.
GENES & DEVELOPMENT (2008)
A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay
Guramrit Singh et al.
PLOS BIOLOGY (2008)
Posttranscriptional gene regulation by spatial rearrangement of the 3′ untranslated region
Andrea B. Eberle et al.
PLOS BIOLOGY (2008)
NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity
Hala Chamieh et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Communication with the Exon-Junction complex and activation of nonsense-mediated decay by human Upf proteins occur in the cytoplasm
Guramrit Singh et al.
MOLECULAR CELL (2007)
Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation
Patrick S. Tarpey et al.
NATURE GENETICS (2007)
Meiotic sex chromosome inactivation
James M. A. Turner
DEVELOPMENT (2007)
An alternative branch of the nonsense-mediated decay pathway
Wai-Kin Chan et al.
EMBO JOURNAL (2007)
A conserved role for cytoplasmic poly(A)-binding protein 1 (PABPC1) in nonsense-mediated mRNA decay
Isabelle Behm-Ansmant et al.
EMBO JOURNAL (2007)
hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay
J Wittmann et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay
I Kashima et al.
GENES & DEVELOPMENT (2006)
Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation
Joachim B. Kunz et al.
RNA (2006)
The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity
L Ballut et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
A faux 3′-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay
N Amrani et al.
NATURE (2004)
Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise
JT Mendell et al.
NATURE GENETICS (2004)
Y14 and hUpf3b form an NMD-activating complex
NH Gehring et al.
MOLECULAR CELL (2003)
Translation is required to remove Y14 from mRNAs in the cytoplasm
J Dostie et al.
CURRENT BIOLOGY (2002)
The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts
WR Wang et al.
EMBO JOURNAL (2001)
Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability
SM Medghalchi et al.
HUMAN MOLECULAR GENETICS (2001)
Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon
J Lykke-Andersen et al.
CELL (2000)