4.5 Article

Numerical investigation of microchannel geometry for effective on-chip biofluid delivery by AC electrothermal effect

Journal

ELECTROPHORESIS
Volume 43, Issue 21-22, Pages 2130-2140

Publisher

WILEY
DOI: 10.1002/elps.202100362

Keywords

AC electrokinetics; AC electrothermal effect; microchannel; micropump

Funding

  1. US NSF CPS/USDA NIFA [2017-67007-26150]
  2. University of Tennessee Initiative for PON/POC Nanobiosensing
  3. University of Tennessee, Institute for a Secure & Sustainable Environment

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This research optimizes the microchannel design for ACET micropumps and achieves effective delivery of biofluids, bringing new progress to the field of on-chip biofluid delivery research and applications.
Although there exist tremendous needs for on-chip biofluid delivery, research in this field has yielded limited numbers of devices for real-world applications. One challenge is the difficulty for micropumps to meet the requirements of being low cost to fabricate, easy to integrate and effective for intended applications at the same time. This research focuses on AC electrothermal (ACET) micropumps based on planar interdigitated electrodes, due to their practicality in fabrication and operation, and compatibility with biochemical fluids. Our prior work has optimized the design of electrode dimensions for a fixed microchannel design. This work finds that microchannel dimensions can also affect ACET micropumps significantly, with respect to flow rate and electric impedance loading. This work first considers the constraints arising from impedance loading by ACET micropumps on power supplies, then the investigation describes several key parameters (threshold height, saturation thickness), to arrive at an appropriate microchannel geometry for the effective delivery of biofluids. The optimized microchannel is expected to incorporate well into a multifunctional lab-chip system to transport biofluids efficiently.

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