Decreased fetal cardiac output in pregnant women with severe SARS-Cov-2 infection

Article Acoustics

Protein expression of angiotensin-converting enzyme 2, a SARS-CoV-2-specific receptor, in fetal and placental tissues throughout gestation: new insight for perinatal counseling

V Faure-Bardon et al.

Summary: The study found that ACE2 expression can be detected in fetal kidney, rectum, and ileum samples from 15 weeks onward, and was barely detectable in fetal lung samples at 15 + 5 weeks' gestation. ACE2 expression was not found in the fetal brain, heart, or cardiac tissues.

ULTRASOUND IN OBSTETRICS & GYNECOLOGY (2021)

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Review Obstetrics & Gynecology

COVID-19 infection in pregnant women: Review of maternal and fetal outcomes

Deemah Salem et al.

Summary: Pregnant women who are COVID-19 positive are typically asymptomatic or exhibit mild-to-moderate symptoms, similar to non-pregnant women. Pneumonia is a common outcome in pregnant women with COVID-19. While there are increased risks for pregnant women with co-morbidities, it is still uncertain whether SARS-CoV-2 infection raises the risk of complications for mothers, fetuses, and newborns.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2021)

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Review Medicine, General & Internal

The Effects of COVID-19 on Placenta and Pregnancy: What Do We Know So Far?

Yin Ping Wong et al.

Summary: The COVID-19 pandemic caused by SARS-CoV-2 has led to global health crisis, with the virus potentially impacting organ systems including the placenta. Although vertical transmission to fetus via the placenta is possible, the protective mechanisms of the placental barrier against viral spread to newborns remain unclear and raise debates.

DIAGNOSTICS (2021)

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Article Obstetrics & Gynecology

Effect of SARS-CoV-2 infection during the second half of pregnancy on fetal growth and hemodynamics: A prospective study

Giuseppe Rizzo et al.

Summary: Pregnancies complicated by SARS-CoV-2 infection do not have a higher risk of fetal growth restriction through impaired placental function, and increased fetal surveillance is not supported based on the findings from this study.

ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA (2021)

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Article Obstetrics & Gynecology

Assessment of fetal Doppler parameters in pregnant women with COVID-19 infection: a prospective case-control study

Sule Goncu Ayhan et al.

Summary: A prospective case-control study was conducted to investigate the effect of SARS-CoV-2 on fetal Doppler parameters. The study found that COVID-19 seems to have no adverse effect on fetoplacental circulation in mild and moderate patients during the acute phase of the infection.

JOURNAL OF PERINATAL MEDICINE (2021)

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Review Obstetrics & Gynecology

Placental histopathology after SARS-CoV-2 infection in pregnancy: a systematic review and meta-analysis

Raffaella Di Girolamo et al.

Summary: This study aimed to report the spectrum of placental pathology findings in pregnancies complicated by SARS-CoV-2 infection. A significant proportion of placentas in pregnant women with SARS-CoV-2 infection showed histopathologic findings suggestive of placental hypoperfusion and inflammation. Future multicenter prospective blinded studies are needed to correlate these placental lesions with pregnancy outcomes.

AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM (2021)

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Article Pathology