4.7 Article

Metal nanoparticles as a promising technology in targeted cancer treatment

Journal

DRUG DELIVERY
Volume 29, Issue 1, Pages 664-678

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/10717544.2022.2039804

Keywords

Cancer treatment; metal nanoparticles; targeting; radiation therapy; hyperthermia

Funding

  1. National Natural Science Foundation of China [81802674]
  2. Natural Science Foundation of Zhejiang Province [LY21H160049]
  3. Medical Health Science and Technology Project of Zhejiang Provincial Health Commission [2021KY482, 2020KY008]

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This article discusses the therapeutic potential of metal nanoparticles as anticancer drugs, including their application in tumor targeting and the risk factors involved in clinical use.
Traditional anticancer treatments have several limitations, but cancer is still one of the deadliest diseases. As a result, new anticancer drugs are required for the treatment of cancer. The use of metal nanoparticles (NPs) as alternative chemotherapeutic drugs is on the rise in cancer research. Metal NPs have the potential for use in a wide range of applications. Natural or surface-induced anticancer effects can be found in metals. The focus of this review is on the therapeutic potential of metal-based NPs. The potential of various types of metal NPs for tumor targeting will be discussed for cancer treatment. The in vivo application of metal NPs for solid tumors will be reviewed. Risk factors involved in the clinical application of metal NPs will also be summarized.

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