4.1 Article

Oral immune-me diate d disorders with malignant potential/association: An overview

Journal

DM DISEASE-A-MONTH
Volume 69, Issue 1, Pages -

Publisher

MOSBY-ELSEVIER
DOI: 10.1016/j.disamonth.2022.101349

Keywords

Dermatitis herpetiformis; Immune-mediated; Lichen planus; Linear IgA disease; Lupus; Malignant potential; Sjogren's syndrome

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Oral immune-mediated disorders are a group of oral diseases or conditions that may result from an abnormality in the individual's normal immune response. Some of these disorders are associated with malignancy. This article provides an overview of several oral diseases, such as oral lichen planus, primary Sjogren's syndrome, systemic lupus erythematosus, dermatitis herpetiformis, and linear immunoglobulin A bullous dermatosis, which are caused by irregularities in the immune system and have the potential to undergo malignant transformation, thereby increasing morbidity and mortality rates.
A group of oral disorders or conditions, which may result from, or could be triggered by an abnormality in the normal immune response of an individual are known as oral immune-mediated disorders. Some of these disorders have malignant potential, while others are associated with malignancy. In this overview, we will discuss a few of the oral diseases (such as oral lichen planus, primary Sjogren's syndrome, systemic lupus erythematosus, dermatitis herpetiformis, and linear immunoglobulin A bullous dermatosis, to name a few), which are caused due to irregularity in the immune system and are either associated with malignancy or capable of undergoing malignant transforming, thereby increasing the morbidity and mortality rate.& COPY; 2022 Elsevier Inc. All rights reserved.

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