Hydroxyapatite-based bio-ceramic of ternary nanocomposites containing cuprous oxide/graphene oxide for biomedical applications

The nanocomposites (NCs) contain a hybrid matrix and reinforcing material that could improve the physicochemical and biological properties of individual compounds. HAP, Cu2O, and GO were prepared separately and combined to fabricate nanocomposite (NCs). The hexagonal symmetry of HAP and the cubic symmetry of Cu2O were confirmed using XRD analysis. The different scanning techniques detected HAP with nanorod shape. The length decreased from 50 to 27 nm. Rv reached 208.4 nm. The effect of the ternary nanocomposite (TNC) against S. aureus and E. coli reached 14.1 +/- 1.1 and 13.2 +/- 1.2 mm, respectively. Furthermore, the cell viability towards the human cell line is around 103 +/- 4%. The enhancement in antibacterial behavior and cell viability confirms the biocompatibility of the TNC to be encouraged for use in biomedical utilizations such as bone regeneration.

Automated summary

Nanocomposites (NCs) are hybrid materials that improve the properties of individual compounds. HAP and Cu2O were confirmed to have hexagonal and cubic symmetry, respectively, through XRD analysis. Different scanning techniques revealed nanorod-shaped HAP. The ternary nanocomposite (TNC) showed significant antibacterial activity and good cell viability.