Journal
DIABETES CARE
Volume 45, Issue 7, Pages 1666-1669Publisher
AMER DIABETES ASSOC
DOI: 10.2337/dc22-0073
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Funding
- University of Virginia
- Societe Francophone du Diabete
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This study assessed the accuracy and clinical relevance of a factory-calibrated CGM in individuals on hemodialysis. The results showed that the CGM had reasonably accurate performance and is clinically relevant for improving diabetes management in this population.
OBJECTIVE Continuous glucose monitoring (CGM) improves diabetes management, but its reliability in individuals on hemodialysis is poorly understood and potentially affected by interstitial and intravascular volume variations. RESEARCH DESIGN AND METHODS We assessed the accuracy of a factory-calibrated CGM by using venous blood glucose measurements (vBGM) during hemodialysis sessions and self-monitoring blood glucose (SMBG) at home. RESULTS Twenty participants completed the protocol. The mean absolute relative difference of the CGM was 13.8% and 14.4%, when calculated on SMBG (n = 684) and on vBGM (n = 624), and 98.7% and 100% of values in the Parkes error grid A/B zones, respectively. Throughout 181 days of CGM monitoring, the median time in range (70-180 mg/dL) was 38.5% (interquartile range 29.3-57.9), with 28.7% (7.8-40.6) of the time >250 mg/dL. CONCLUSIONS The overall performance of a factory-calibrated CGM appears reasonably accurate and clinically relevant for use in practice by individuals on hemodialysis and health professionals to improve diabetes management.
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