4.0 Review

Managing the Behavioral and Psychological Symptoms of Dementia

Related references

Note: Only part of the references are listed.
Article Geriatrics & Gerontology

Systematic review of pharmacological interventions for people with Lewy body dementia

Katrina E. Watts et al.

Summary: This article systematically reviews the pharmacological management of Lewy body dementia (LBD) and provides evidence-based recommendations and clinical guidelines for its clinical care. The study identifies the efficacy of various medications in managing cognitive, neuropsychiatric, and hallucination symptoms associated with LBD and Parkinson's Disease Dementia (PDD). The findings support the use of specific medications for symptom management in LBD and PDD.

AGING & MENTAL HEALTH (2023)

Article Psychology, Clinical

Managing depressive symptoms in people with mild cognitive impairment and mild dementia with a multicomponent psychotherapy intervention: a randomized controlled trial

Johanne B. Tonga et al.

Summary: The study evaluated the CORDIAL program and found that this psychosocial intervention effectively reduced depressive symptoms in MCI and dementia patients, with effects persisting for up to 6 months post-intervention.

INTERNATIONAL PSYCHOGERIATRICS (2021)

Article Geriatrics & Gerontology

Less Is More: The Impact of Deprescribing Psychotropic Drugs on Behavioral and Psychological Symptoms and Daily Functioning in Nursing Home Patients. Results From the Cluster-Randomized Controlled COSMOS Trial

Marie H. Gedde et al.

Summary: The study found that medication reviews using collegial mentoring and systematic clinical evaluation resulted in a reduction in psychotropic drug prescriptions, improved activities of daily living, and did not negatively affect behavioral and psychological symptoms of dementia.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2021)

Review Pharmacology & Pharmacy

Discontinuation of antipsychotics treatment for elderly patients within a specialized behavioural unit: a retrospective review

Raymond LinBin Gao et al.

Summary: The study found that the use of high dose antipsychotics is associated with worse discontinuation outcomes in hospitalized dementia patients, suggesting limitations on the daily dose of certain medications.

INTERNATIONAL JOURNAL OF CLINICAL PHARMACY (2021)

Article Psychiatry

The Psychopharmacology Algorithm Project at the Harvard South Shore Program: An update on management of behavioral and psychological symptoms in dementia

Anderson Chen et al.

Summary: This article updates algorithms for the use of psychopharmacologic agents in geriatric patients with dementia, proposing different treatment approaches for emergent, urgent, and non-urgent settings. Recommendations for specific medications like olanzapine and trazodone are provided based on the severity of the situation.

PSYCHIATRY RESEARCH (2021)

Article Clinical Neurology

Psychosis in neurodegenerative disease: differential patterns of hallucination and delusion symptoms

Georges Naasan et al.

Summary: This study compared the rates and content of psychosis in patients with different neurodegenerative diseases. It found that patients with Lewy body disease/Alzheimer's disease pathology were more likely to have hallucinations, while patients with FTLD-TDP were more likely to have delusions. The data suggests that the nature and content of psychosis can provide valuable information about underlying neurodegenerative pathology.

BRAIN (2021)

Review Clinical Neurology

Pharmacotherapy for Frontotemporal Dementia

Rita Khoury et al.

Summary: Frontotemporal dementia is a diverse spectrum of neurodegenerative disorders with genetic mutations contributing to its heritability. Current treatments are limited by lack of approval and potential side effects, with emerging therapies targeting specific genes and proteins for disease modification. Advancements in understanding the disease's pathophysiology and designing better clinical trials are crucial for improving outcomes.

CNS DRUGS (2021)

Review Clinical Neurology

Visual hallucinations in neurological and ophthalmological disease: pathophysiology and management

John O'Brien et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2020)

Review Pharmacology & Pharmacy

Pharmacotherapy of Behavioral and Psychological Symptoms of Dementia: State of the Art and Future Progress

Radoslaw Magierski et al.

FRONTIERS IN PHARMACOLOGY (2020)

Review Clinical Neurology

Treatment Options for Agitation in Dementia

John M. Ringman et al.

CURRENT TREATMENT OPTIONS IN NEUROLOGY (2019)

Review Psychiatry

Advances in Management of Neuropsychiatric Syndromes in Neurodegenerative Diseases

Jeffrey Cummings et al.

CURRENT PSYCHIATRY REPORTS (2019)

Article Geriatrics & Gerontology

Using electronic health records to estimate the prevalence of agitation in Alzheimer disease/dementia

Rachel Halpern et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2019)

Review Pharmacology & Pharmacy

The Pharmacology of Visual Hallucinations in Synucleinopathies

Mirella Russo et al.

FRONTIERS IN PHARMACOLOGY (2019)

Article Clinical Neurology

Aripiprazole for the treatment of psychotic symptoms in patients with dementia with Lewy bodies: a case series

Yuka Sugawara Kikuchi et al.

NEUROPSYCHIATRIC DISEASE AND TREATMENT (2019)

Article Clinical Neurology

Citalopram Improves Obsessive Compulsive Crossword Puzzling in Frontotemporal Dementia

Sebastian Meyer et al.

CASE REPORTS IN NEUROLOGY (2019)

Article Geriatrics & Gerontology

What Behavioral and Psychological Symptoms of Dementia Affect Caregiver Burnout?

Kazuko Hiyoshi-Taniguchi et al.

CLINICAL GERONTOLOGIST (2018)

Review Pharmacology & Pharmacy

Pharmacological treatments for alleviating agitation in dementia: a systematic review and network meta-analysis

Khachen Kongpakwattana et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2018)

Article Clinical Neurology

Sequential drug treatment algorithm for agitation and aggression in Alzheimer's and mixed dementia

Simon J. C. Davies et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2018)

Article Geriatrics & Gerontology

Factors Associated with the Caregivers' Desire to Institutionalize Persons with Dementia: A Cross-Sectional Study

Sophie Vandepitte et al.

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2018)

Review Medicine, General & Internal

Pharmacological interventions for apathy in Alzheimer's disease

Myuri T. Ruthirakuhan et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2018)

Review Medicine, General & Internal

Antidepressants for treating depression in dementia

Robert Dudas et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2018)

Review Medicine, General & Internal

Valproate preparations for agitation in dementia

Sarah F. Baillon et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2018)

Review Psychiatry

Antipsychotic Use in Dementia: Is There a Problem and Are There Solutions?

Julia Kirkham et al.

CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE (2017)

Review Pharmacology & Pharmacy

An update on the advancements in the treatment of agitation in Alzheimer's disease

Anton P. Porsteinsson et al.

EXPERT OPINION ON PHARMACOTHERAPY (2017)

Review Geriatrics & Gerontology

The relationship of specific items on the Neuropsychiatric Inventory to caregiver burden in dementia: a systematic review

Toril Marie Terum et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2017)

Letter Pharmacology & Pharmacy

Aripiprazole Improves Psychotic, Cognitive, and Motor Symptoms in a Patient With Lewy Body Dementia

Cho Lee et al.

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2017)

Article Geriatrics & Gerontology

Efficacy and Safety of Citalopram Compared to Atypical Antipsychotics on Agitation in Nursing Home Residents With Alzheimer Dementia

Giovanni Viscogliosi et al.

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION (2017)

Review Clinical Neurology

Pharmacological Therapy for Apathy in Alzheimer's Disease: A Systematic Review and Meta-Analysis

Amir A. Sepehry et al.

CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES (2017)

Article Clinical Neurology

Low-dose Lithium Treatment for Agitation and Psychosis in Alzheimer Disease and Frontotemporal Dementia: A Case Series

Davangere P. Devanand et al.

ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2017)

Review Clinical Neurology

Serotonergic drugs for the treatment of neuropsychiatric symptoms in dementia

Radoslaw Magierski et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2016)

Article Clinical Neurology

The prevalence of neuropsychiatric symptoms in Alzheimer's disease: Systematic review and meta-analysis

Qing-Fei Zhao et al.

JOURNAL OF AFFECTIVE DISORDERS (2016)

Review Clinical Neurology

Serotonergic drugs for the treatment of neuropsychiatric symptoms in dementia

Radoslaw Magierski et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2016)

Article Neurosciences

Time Trends in Antipsychotic Drug Use in Patients with Dementia: A Nationwide Study

Ane Norgaard et al.

JOURNAL OF ALZHEIMERS DISEASE (2016)

Article Geriatrics & Gerontology

Time to Response to Citalopram Treatment for Agitation in Alzheimer Disease

Daniel Weintraub et al.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2015)

Article Biology

Circadian rhythm in Alzheimer disease after trazodone use

Talyta C. Grippe et al.

CHRONOBIOLOGY INTERNATIONAL (2015)

Article Medicine, General & Internal

Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia A Randomized Clinical Trial

Jeffrey L. Cummings et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)

Article Clinical Neurology

Tetrahydrocannabinol for neuropsychiatric symptoms in dementia A randomized controlled trial

Geke A. H. van den Elsen et al.

NEUROLOGY (2015)

Article Medical Laboratory Technology

Therapeutic Drug Monitoring of Selective Serotonin Reuptake Inhibitors in Elderly Patients

Monica Hermann et al.

THERAPEUTIC DRUG MONITORING (2015)

Article Medicine, General & Internal

Effect of Citalopram on Agitation in Alzheimer Disease The CitAD Randomized Clinical Trial

Anton P. Porsteinsson et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)

Review Psychology, Clinical

Pharmacological treatments for neuropsychiatric symptoms of dementia in long-term care: a systematic review

Dallas P. Seitz et al.

INTERNATIONAL PSYCHOGERIATRICS (2013)

Article Psychology, Clinical

Safety and Efficacy of Methylphenidate for Apathy in Alzheimer's Disease: A Randomized, Placebo-Controlled Trial

Paul B. Rosenberg et al.

JOURNAL OF CLINICAL PSYCHIATRY (2013)

Article Geriatrics & Gerontology

Managing abnormal eating behaviours in frontotemporal lobar degeneration patients with topiramate

Shunichiro Shinagawa et al.

PSYCHOGERIATRICS (2013)

Review Medicine, General & Internal

Withdrawal versus continuation of chronic antipsychotic drugs for behavioural and psychological symptoms in older people with dementia

Tom Declercq et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2013)

Article Psychiatry

Atypical Antipsychotic Use in Patients With Dementia: Managing Safety Concerns

Martin Steinberg et al.

AMERICAN JOURNAL OF PSYCHIATRY (2012)

Article Psychiatry

Risk of Mortality Among Individual Antipsychotics in Patients With Dementia

Helen C. Kales et al.

AMERICAN JOURNAL OF PSYCHIATRY (2012)

Article Psychiatry

Meta-Analysis of Nonpharmacological Interventions for Neuropsychiatric Symptoms of Dementia

Henry Brodaty et al.

AMERICAN JOURNAL OF PSYCHIATRY (2012)

Letter Pharmacology & Pharmacy

Treatment of Indiscriminate, Inappropriate Sexual Behavior in Frontotemporal Dementia With Carbamazepine

Connie E. Poetter et al.

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2012)

Letter Clinical Neurology

Reversal of abnormal eating and drinking behaviour in a frontotemporal lobar degeneration patient using low-dose topiramate

Peter J. Nestor

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2012)

Article Medicine, General & Internal

Relapse Risk after Discontinuation of Risperidone in Alzheimer's Disease

D. P. Devanand et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Review Medicine, General & Internal

Antidepressants for agitation and psychosis in dementia

D. P. Seitz et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2011)

Article Geriatrics & Gerontology

Sertraline for the Treatment of Depression in Alzheimer Disease

Paul B. Rosenberg et al.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2010)

Article Geriatrics & Gerontology

Sertraline for the Treatment of Depression in Alzheimer Disease: Week-24 Outcomes

Daniel Weintraub et al.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2010)

Review Geriatrics & Gerontology

Nonpharmacological Therapies in Alzheimer's Disease: A Systematic Review of Efficacy

Javier Olazaran et al.

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2010)

Letter Clinical Neurology

Behavioural abnormalities associated with rapid deterioration of language functions in semantic dementia respond to sertraline

C. I. Prodan et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2009)

Article Health Care Sciences & Services

Predictors of Nursing Home Admission for Persons with Dementia

Joseph E. Gaugler et al.

MEDICAL CARE (2009)

Review Geriatrics & Gerontology

Inappropriate Sexual Behaviors in Cognitively Impaired Older Individuals

David R. R. Guay

AMERICAN JOURNAL OF GERIATRIC PHARMACOTHERAPY (2008)

Article Medicine, General & Internal

Antipsychotic therapy and short-term serious events in older adults with dementia

Paula A. Rochon et al.

ARCHIVES OF INTERNAL MEDICINE (2008)

Article Behavioral Sciences

Topiramate may modulate alcohol abuse but not other compulsive behaviors in frontotemporal dementia - Case report

Marcelo Cruz et al.

COGNITIVE AND BEHAVIORAL NEUROLOGY (2008)

Article Clinical Neurology

Serotonin-1A receptors in frontotemporal dementia compared with controls

Krista L. Lanctot et al.

PSYCHIATRY RESEARCH-NEUROIMAGING (2007)

Article Clinical Neurology

Inappropriate sexual behaviour in a case of ALS and FTD: Successful treatment with sertraline

Johanna M. H. Anneser et al.

AMYOTROPHIC LATERAL SCLEROSIS (2007)

Article Geriatrics & Gerontology

Preliminary findings: Behavioral worsening on donepezil in patients with frontotemporal dementia

Mario F. Mendez et al.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2007)

Article Geriatrics & Gerontology

Design of depression in Alzheimer's disease study-2

Barbara K. Martin et al.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2006)

Article Medicine, General & Internal

Effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease

Lon S. Schneider et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Geriatrics & Gerontology

Efficacy and adverse effects of atypical antipsychotics for dementia: Meta-analysis of randomized, placebo-controlled trials

LS Schneider et al.

AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY (2006)

Article Geriatrics & Gerontology

An exploratory open-label trial of ziprasidone for the treatment of behavioral and psychological symptoms of dementia

Fabio Lopes Rocha et al.

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2006)

Review Medicine, General & Internal

Risk of death with atypical antipsychotic drug treatment for dementia - Meta-analysis of randomized placebo-controlled trials

LS Schneider et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)

Article Geriatrics & Gerontology

Inappropriate sexual behaviors in dementia

B Black et al.

JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY (2005)

Article Clinical Neurology

Stereotypical movements and frontotemporal dementia

MF Mendez et al.

MOVEMENT DISORDERS (2005)

Article Geriatrics & Gerontology

Frontotemporal dementia: A randomised, controlled trial with trazodone

F Lebert et al.

DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2004)

Article Geriatrics & Gerontology

Behavioural disturbances in dementia patients and quality of the marital relationship

ME de Vugt et al.

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2003)