4.8 Article

Distinct inhibitory pathways control velocity and directional tuning in the mouse retina

Related references

Note: Only part of the references are listed.
Article Cell Biology

Gain control by sparse ultra-slow glycinergic synapses

Varsha Jain et al.

Summary: Glycinergic inhibition plays a crucial role in shaping the response properties of SACs in the retina, and is predominantly derived from specific amacrine cells in both the ON and OFF retinal pathways. Glycinergic inputs effectively control the output gain of SACs by summing and expanding their range of direction computation.

CELL REPORTS (2022)

Article Neurosciences

An offset ON-OFF receptive field is created by gap junctions between distinct types of retinal ganglion cells

Sam Cooler et al.

Summary: A systematic spatial offset between ON and OFF receptive subfields in F-mini-ON retinal ganglion cells was discovered, originating from a network of electrical synapses instead of dendritic positions. The asymmetry in morphology and connectivity of these RGCs explains their receptive field offset, affecting the precision of edge-location representation. This RGC network forms a new electrical channel combining the ON and OFF feedforward pathways within the output layer of the retina.

NATURE NEUROSCIENCE (2021)

Article Multidisciplinary Sciences

Rapid multi-directed cholinergic transmission in the central nervous system

Santhosh Sethuramanujam et al.

Summary: The study reveals that acetylcholine signals are transmitted through a rapid co-activation mechanism, activating receptors on multiple neurons surrounding the release site. Additionally, while acetylcholine signals are direction-selective locally, they do not show global directionality, facilitating information transfer at a local scale.

NATURE COMMUNICATIONS (2021)

Article Cell Biology

Cholinergic feedback to bipolar cells contributes to motion detection in the mouse retina

Chase B. Hellmer et al.

Summary: Cholinergic feedback from starburst amacrine cells to certain bipolar cells via alpha-7 nicotinic acetylcholine receptors promotes direction-selective signaling, contributing to motion detection. These findings highlight the role of bipolar cells in enhancing direction-selective signaling in retinal microcircuits.

CELL REPORTS (2021)

Article Neurosciences

Direction selectivity in retinal bipolar cell axon terminals

Akihiro Matsumoto et al.

Summary: Through two-photon glutamate imaging, it was discovered that direction selectivity arises early at bipolar cell outputs, with individual bipolar cells containing distinct populations of axon terminal boutons with different preferred directions. Tuning at these boutons relies on cholinergic excitation and GABAergic inhibition, contributing to the incremental refinement of directional tuning in the excitatory visual pathway.

NEURON (2021)

Article Biochemistry & Molecular Biology

Spatiotemporally Asymmetric Excitation Supports Mammalian Retinal Motion Sensitivity

Akihiro Matsumoto et al.

CURRENT BIOLOGY (2019)

Article Biochemistry & Molecular Biology

A Dense Starburst Plexus Is Critical for Generating Direction Selectivity

Ryan D. Morrie et al.

CURRENT BIOLOGY (2018)

Article Biochemistry & Molecular Biology

A Role for Mouse Primary Visual Cortex in Motion Perception

Tiago Marques et al.

CURRENT BIOLOGY (2018)

Article Multidisciplinary Sciences

Cortical direction selectivity emerges at convergence of thalamic synapses

Anthony D. Lien et al.

NATURE (2018)

Review Neurosciences

Neural Mechanisms of Motion Processing in the Mammalian Retina

Wei Wei

ANNUAL REVIEW OF VISION SCIENCE, VOL 4 (2018)

Article Neurosciences

Comparison of optomotor and optokinetic reflexes in mice

Friedrich Kretschmer et al.

JOURNAL OF NEUROPHYSIOLOGY (2017)

Article Cell Biology

Biophysical Variation within the M1 Type of Ganglion Cell Photoreceptor

Alan J. Emanuel et al.

CELL REPORTS (2017)

Article Neurosciences

A Dynamic Clamp on Every Rig

Niraj S. Desai et al.

ENEURO (2017)

Article Biochemistry & Molecular Biology

Role for Visual Experience in the Development of Direction-Selective Circuits

Remi Bos et al.

CURRENT BIOLOGY (2016)

Review Neurosciences

Development of synaptic connectivity in the retinal direction selective circuit

Ryan D. Morrie et al.

CURRENT OPINION IN NEUROBIOLOGY (2016)

Article Multidisciplinary Sciences

The functional diversity of retinal ganglion cells in the mouse

Tom Baden et al.

NATURE (2016)

Article Multidisciplinary Sciences

Species-specific wiring for direction selectivity in the mammalian retina

Huayu Ding et al.

NATURE (2016)

Editorial Material Biochemistry & Molecular Biology

Elementary motion detectors

Mark Frye

CURRENT BIOLOGY (2015)

Article Neurosciences

Inhibitory input to the direction-selective ganglion cell is saturated at low contrast

Mikhail Y. Lipin et al.

JOURNAL OF NEUROPHYSIOLOGY (2015)

Article Neurosciences

Function and Circuitry of VIP+ Interneurons in the Mouse Retina

Silvia J. H. Park et al.

JOURNAL OF NEUROSCIENCE (2015)

Article Cell Biology

An Amacrine Cell Circuit for Signaling Steady Illumination in the Retina

Jason Jacoby et al.

CELL REPORTS (2015)

Review Neurosciences

Retinal ganglion cell maps in the brain: implications for visual processing

Onkar S. Dhande et al.

CURRENT OPINION IN NEUROBIOLOGY (2014)

Article Multidisciplinary Sciences

Space-time wiring specificity supports direction selectivity in the retina

Jinseop S. Kim et al.

NATURE (2014)

Article Neurosciences

Genetic Dissection of Retinal Inputs to Brainstem Nuclei Controlling Image Stabilization

Onkar S. Dhande et al.

JOURNAL OF NEUROSCIENCE (2013)

Review Neurosciences

Direction selectivity in the retina: symmetry and asymmetry in structure and function

David I. Vaney et al.

NATURE REVIEWS NEUROSCIENCE (2012)

Review Neurosciences

Receptor targets of amacrine cells

Chi Zhang et al.

VISUAL NEUROSCIENCE (2012)

Review Neurosciences

Seeing Things in Motion: Models, Circuits, and Mechanisms

Alexander Borst et al.

NEURON (2011)

Article Neurosciences

Parallel Mechanisms Encode Direction in the Retina

Stuart Trenholm et al.

NEURON (2011)

Article Neurosciences

Quantitative analysis of spontaneous saccade-like rapid eye movements in C57BL/6 mice

Tomoya Sakatani et al.

NEUROSCIENCE RESEARCH (2007)

Article Neurosciences

Robust directional computation in on-off directionally selective ganglion cells of rabbit retina

Norberto M. Grzywacz et al.

VISUAL NEUROSCIENCE (2007)

Article Multidisciplinary Sciences

Mechanisms and circuitry underlying directional selectivity in the retina

SI Fried et al.

NATURE (2002)