Journal
COMPUTERS IN BIOLOGY AND MEDICINE
Volume 143, Issue -, Pages -Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.compbiomed.2022.105321
Keywords
MRI; MR Image reconstruction; Undersampled MRI; Undersampled MR Reconstruction; Radial sampling reconstruction; Deep learning
Categories
Funding
- European Structural and Investment Funds (ESF) under the programme Sachsen-Anhalt WISSENSCHAFT Internationalisierung [ZS/2016/08/80646]
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This study proposes a deep learning-based framework for MR image reconstruction, which can effectively reconstruct highly undersampled images without artifact. The framework shows robustness to different sampling patterns and preserves brain pathology during training.
MRI is an inherently slow process, which leads to long scan time for high-resolution imaging. The speed of acquisition can be increased by ignoring parts of the data (undersampling). Consequently, this leads to the degradation of image quality, such as loss of resolution or introduction of image artefacts. This work aims to reconstruct highly undersampled Cartesian or radial MR acquisitions, with better resolution and with less to no artefact compared to conventional techniques like compressed sensing. In recent times, deep learning has emerged as a very important area of research and has shown immense potential in solving inverse problems, e.g. MR image reconstruction. In this paper, a deep learning based MR image reconstruction framework is proposed, which includes a modified regularised version of ResNet as the network backbone to remove artefacts from the undersampled image, followed by data consistency steps that fusions the network output with the data already available from undersampled k-space in order to further improve reconstruction quality. The performance of this framework for various undersampling patterns has also been tested, and it has been observed that the framework is robust to deal with various sampling patterns, even when mixed together while training, and results in very high quality reconstruction, in terms of high SSIM (highest being 0.990 +/- 0.006 for acceleration factor of 3.5), while being compared with the fully sampled reconstruction. It has been shown that the proposed framework can successfully reconstruct even for an acceleration factor of 20 for Cartesian (0.968 +/- 0.005) and 17 for radially (0.962 +/- 0.012) sampled data. Furthermore, it has been shown that the framework preserves brain pathology during reconstruction while being trained on healthy subjects.
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