Detection of COVID-19 severity using blood gas analysis parameters and Harris hawks optimized extreme learning machine

Coronavirus disease-2019 (COVID-19) has made the world more cautious about widespread viruses, and a tragic pandemic that was caused by a novel coronavirus has harmed human beings in recent years. The new coronavirus pneumonia outbreak is spreading rapidly worldwide. We collect arterial blood samples from 51 patients with a COVID-19 diagnosis. Blood gas analysis is performed using a Siemens RAPID Point 500 blood gas analyzer. To accurately determine the factors that play a decisive role in the early recognition and discrimination of COVID-19 severity, a prediction framework that is based on an improved binary Harris hawk optimization (HHO) algorithm in combination with a kernel extreme learning machine is proposed in this paper. This method uses specular reflection learning to improve the original HHO algorithm and is referred to as HHOSRL. The experimental results show that the selected indicators, such as age, partial pressure of oxygen, oxygen saturation, sodium ion concentration, and lactic acid, are essential for the early accurate assessment of COVID-19 severity by the proposed feature selection method. The simulation results show that the established methodlogy can achieve promising performance. We believe that our proposed model provides an effective strategy for accurate early assessment of COVID-19 and distinguishing disease severity. The codes of HHO will be updated in https://aliasgh arheidari.com/HHO.html.

Automated summary

This study proposes a method for early and accurate assessment of COVID-19 severity by collecting arterial blood samples from patients and using an improved binary Harris hawk optimization algorithm combined with a kernel extreme learning machine. The experimental results show that indicators such as age, partial pressure of oxygen, oxygen saturation, sodium ion concentration, and lactic acid play a crucial role in the assessment of COVID-19 severity.