Related references
Note: Only part of the references are listed.Intestinal P-gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications
Maciej J. Zamek-Gliszczynski et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2021)
Short-chain fatty acids exert opposite effects on the expression and function of p-glycoprotein and breast cancer resistance protein in rat intestine
Qiu-shi Xie et al.
ACTA PHARMACOLOGICA SINICA (2021)
A Microdose Cocktail to Evaluate Drug Interactions in Patients with Renal Impairment
Daniel A. Tatosian et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2021)
Assessing Transporter-Mediated Natural Product-Drug Interactions Via In vitro-In Vivo Extrapolation: Clinical Evaluation With a Probe Cocktail
James T. Nguyen et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2021)
Pre-incubation with OATP1B1 and OATP1B3 inhibitors potentiates inhibitory effects in physiologically relevant sandwich-cultured primary human hepatocytes
Taleah Farasyn et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2021)
Regulation of OATP1B1 Function by Tyrosine Kinase-mediated Phosphorylation
Elizabeth R. Hayden et al.
CLINICAL CANCER RESEARCH (2021)
Molecular Regulation of Canalicular ABC Transporters
Amel Ben Saad et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Regulatory mechanisms of the bile salt export pump (BSEP/ABCB11) and its role in related diseases
Tengqi Ren et al.
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2021)
Influence of YES1 Kinase and Tyrosine Phosphorylation on the Activity of OCT1
Muhammad Erfan Uddin et al.
FRONTIERS IN PHARMACOLOGY (2021)
Exploring the Use of Serum-Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Hepatic Cytochromes P450 and Organic Anion Transporting Polypeptides
A. David Rodrigues et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2021)
RNA editing enzyme ADAR1 governs the circadian expression of P-glycoprotein in human renal cells by regulating alternative splicing of the ABCB1 gene
Yuji Omata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Protein kinase C regulates organic anion transporter 1 through phosphorylating ubiquitin ligase Nedd4-2
Zhou Yu et al.
BMC MOLECULAR AND CELL BIOLOGY (2021)
Unraveling pleiotropic effects of rifampicin by using physiologically based pharmacokinetic modeling: Assessing the induction magnitude of P-glycoprotein-cytochrome P450 3A4 dual substrates
Xian Pan et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2021)
Mapping the miRNA-mRNA Interactome in Human Hepatocytes and Identification of Functional mirSNPs in Pharmacogenes
Nicholas R. Powell et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2021)
Expression and Function of Organic Anion Transporting Polypeptides in the Human Brain: Physiological and Pharmacological Implications
Anima M. Schaefer et al.
PHARMACEUTICS (2021)
PBPK Model of Coproporphyrin I: Evaluation of the Impact of SLCO1B1 Genotype, Ethnicity, and Sex on its Inter-Individual Variability
Hiroyuki Takita et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2021)
Insulin-like growth factor 1 modulates the phosphorylation, expression, and activity of organic anion transporter 3 through protein kinase A signaling pathway
Jinghui Zhang et al.
ACTA PHARMACEUTICA SINICA B (2020)
Alternative Polyadenylation of ABC Transporters of the C-Family (ABCC1, ABCC2, ABCC3) and Implications on Posttranscriptional Micro-RNA Regulation
Oliver Bruhn et al.
MOLECULAR PHARMACOLOGY (2020)
Long-noncoding RNAs (lncRNAs) in drug metabolism and disposition, implications in cancer chemo-resistance
Yue Wang et al.
ACTA PHARMACEUTICA SINICA B (2020)
Stimulatory effect on the transport mediated by organic anion transporting polypeptide 2B1
Jiro Ogura et al.
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2020)
Alternative Splicing of the SLCO1B1 Gene: An Exploratory Analysis of Isoform Diversity in Pediatric Liver
Bianca D. van Groen et al.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2020)
Induction of Human Intestinal and Hepatic Organic Anion Transporting Polypeptides: Where Is the Evidence for Its Relevance in Drug-Drug Interactions?
A. David Rodrigues et al.
DRUG METABOLISM AND DISPOSITION (2020)
Suppression of P-glycoprotein by cigarette smoke extract in human lung-derived A549/P-gp cells
Mikihisa Takano et al.
DRUG METABOLISM AND PHARMACOKINETICS (2020)
S-acylation modulates the function of the apical sodium-dependent bile acid transporter in human cells
Alexander L. Ticho et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Profiling of Drug-Metabolizing Enzymes and Transporters in Human Tissue Biopsy Samples: A Review of the Literature
A. David Rodrigues et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2020)
Proteasome Inhibitors Bortezomib and Carfilzomib Stimulate the Transport Activity of Human Organic Anion Transporter 1
Yunzhou Fan et al.
MOLECULAR PHARMACOLOGY (2020)
Gestational Age-Dependent Abundance of Human Placental Transporters as Determined by Quantitative Targeted Proteomics
Olena Anoshchenko et al.
DRUG METABOLISM AND DISPOSITION (2020)
Regulation of Organic Anion Transporting Polypeptide 2B1 Expression by MicroRNA in the Human Liver
Ayaka Tajiri et al.
MOLECULAR PHARMACEUTICS (2020)
Post-transcriptional regulation of OATP2B1 transporter by a microRNA, miR-24
Weiyi Liu et al.
DRUG METABOLISM AND PHARMACOKINETICS (2020)
Role of OATP1B1 and OATP1B3 in Drug-Drug Interactions Mediated by Tyrosine Kinase Inhibitors
Dominique A. Garrison et al.
PHARMACEUTICS (2020)
Ubiquitin-specific peptidase 8 regulates the trafficking and stability of the human organic anion transporter 1
Jinghui Zhang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2020)
Organic Cation Transporters in the Lung-Current and Emerging (Patho)Physiological and Pharmacological Concepts
Mohammed Ali Selo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Genetic variants of SLCO1B7 are of relevance for the transport function of OATP1B3-1B7
Henriette E. Meyer zu Schwabedissen et al.
PHARMACOLOGICAL RESEARCH (2020)
Expression of clinically relevant drug-metabolizing enzymes along the human intestine and their correlation to drug transporters and nuclear receptors: An intra-subject analysis
Anja Fritz et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2019)
Dysregulation of Mucosal Membrane Transporters and Drug-Metabolizing Enzymes in Ulcerative Colitis
Pascal Erdmann et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2019)
Regulation of OCT2 transcriptional repression by histone acetylation in renal cell carcinoma
Qianying Zhu et al.
EPIGENETICS (2019)
Preincubation With Everolimus and Sirolimus Reduces Organic Anion-Transporting Polypeptide (OATP)1B1-and 1B3-Mediated Transport Independently of mTOR Kinase Inhibition: Implication in Assessing OATP1B1-and OATP1B3-Mediated Drug-Drug Interactions
Taleah Farasyn et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2019)
Characterization of Plasma Membrane Localization and Phosphorylation Status of Organic Anion Transporting Polypeptide (OATP) 1B1 c.521 T>C Nonsynonymous Single-Nucleotide Polymorphism
Alexandra Crowe et al.
PHARMACEUTICAL RESEARCH (2019)
Toward a Consensus on Applying Quantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper
Bhagwat Prasad et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2019)
Transcriptional and Post-Transcriptional Regulation of Duodenal P-Glycoprotein and MRP2 in Healthy Human Subjects after Chronic Treatment with Rifampin and Carbamazepine
Susanne Brueck et al.
MOLECULAR PHARMACEUTICS (2019)
microRNA-206 modulates the hepatic expression of the organic anion-transporting polypeptide 1B1
Taemer El Saadany et al.
LIVER INTERNATIONAL (2019)
Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo
Congrong Niu et al.
DRUG METABOLISM AND DISPOSITION (2019)
Intestinal breast cancer resistance protein (BCRP) requires Janus kinase 3 activity for drug efflux and barrier functions in obesity
Jayshree Mishra et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Role of N-glycosylation in the expression of human SLC26A2 and A3 anion transport membrane glycoproteins
Chloe L. Rapp et al.
BIOCHEMISTRY AND CELL BIOLOGY (2019)
From Endogenous Compounds as Biomarkers to Plasma-Derived Nanovesicles as Liquid Biopsy; Has the Golden Age of Translational Pharmacokinetics-Absorption, Distribution, Metabolism, Excretion-Drug-Drug Interaction Science Finally Arrived?
David Rodrigues et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2019)
Clinical Aspects of Transporter-Mediated Drug-Drug Interactions
Arne Gessner et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2019)
The impact of cigarette smoke exposure, COPD, or asthma status on ABC transporter gene expression in human airway epithelial cells
Jennifer A. Aguiar et al.
SCIENTIFIC REPORTS (2019)
Activation of Protein Kinase A Stimulates SUMOylation, Expression, and Transport Activity of Organic Anion Transporter 3
Haoxun Wang et al.
AAPS JOURNAL (2019)
Physiologically-Based Pharmacokinetic Modeling Approach to Predict Rifampin-Mediated Intestinal P-Glycoprotein Induction
Shinji Yamazaki et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2019)
Regulation of P-glycoprotein by Bajijiasu in vitro and in vivo by activating the Nrf2-mediated signalling pathway
Xin Yang et al.
PHARMACEUTICAL BIOLOGY (2019)
Expanded Physiologically-Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion Transporting Polypeptide 1B Induction
Ryuta Asaumi et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2019)
Relationship between DNA Methylation in the 5′ CpG Island of the SLC47A1 (Multidrug and Toxin Extrusion Protein MATE1) Gene and Interindividual Variability in MATE1 Expression in the Human Liver
Toshihiro Tanaka et al.
MOLECULAR PHARMACOLOGY (2018)
LST-3TM12 is a member of the OATP1B family and a functional transporter
Vanessa Malagnino et al.
BIOCHEMICAL PHARMACOLOGY (2018)
Cytochrome P450 3A Induction Predicts P-glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine
Justin D. Lutz et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)
Cytochrome P450 3A Induction Predicts P-glycoprotein Induction; Part 1: Establishing Induction Relationships Using Ascending Dose Rifampin
Justin D. Lutz et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)
Transporter-Mediated Alterations in Patients With NASH Increase Systemic and Hepatic Exposure to an OATP and MRP2 Substrate
Izna Ali et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)
Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium
Raymond Evers et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)
Beyond Competitive Inhibition: Regulation of ABC Transporters by Kinases and Protein-Protein Interactions as Potential Mechanisms of Drug-Drug Interactions
Rebecca R. Crawford et al.
DRUG METABOLISM AND DISPOSITION (2018)
Glucocorticoids modulate multidrug resistance transporters in the first trimester human placenta
Phetcharawan Lye et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2018)
Farnesoid X Receptor Agonists Obeticholic Acid and Chenodeoxycholic Acid Increase Bile Acid Efflux in Sandwich-Cultured Human Hepatocytes: Functional Evidence and Mechanisms
Cen Guo et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2018)
Genetic variations of the xenoreceptors NR1I2 and NR1I3 and their effect on drug disposition and response variability
Litaty Cephanoee Mbatchi et al.
PHARMACOGENOMICS (2018)
Post-translational modifications of transporters
Lindsay C. Czuba et al.
PHARMACOLOGY & THERAPEUTICS (2018)
JNK-AKT-NF-kappa B controls P-glycoprotein expression to attenuate the cytotoxicity of deoxynivalenol in mammalian cells
Xiaoming Li et al.
BIOCHEMICAL PHARMACOLOGY (2018)
Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance
Maciej J. Zamek-Gliszczynski et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)
Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective
J. Gerry Kenna et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)
Expression of MATE1, P-gp, OCTN1 and OCTN2, in epithelial and immune cells in the lung of COPD and healthy individuals
Tove Berg et al.
RESPIRATORY RESEARCH (2018)
Using quantitative systems pharmacology to evaluate the drug efficacy of COX-2 and 5-LOX inhibitors in therapeutic situations
Christoph Thiel et al.
NPJ SYSTEMS BIOLOGY AND APPLICATIONS (2018)
PBPK Modeling of Coproporphyrin I as an Endogenous Biomarker for Drug Interactions Involving Inhibition of Hepatic OATP1B1 and OATP1B3
Takashi Yoshikado et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2018)
Endogenous Probes for Drug Transporters: Balancing Vision With Reality
A. D. Rodrigues et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)
Soluble uric acid increases PDZK1 and ABCG2 expression in human intestinal cell lines via the TLR4-NLRP3 inflammasome and PI3K/Akt signaling pathway
Mo Chen et al.
ARTHRITIS RESEARCH & THERAPY (2018)
Epigenetic regulation of drug transporter expression in human tissues
Takeshi Hirota et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2017)
A novel miR-203-DNMT3b-ABCG2 regulatory pathway predisposing colorectal cancer development
Kenneth K. W. To et al.
MOLECULAR CARCINOGENESIS (2017)
Protein Kinases C-Mediated Regulations of Drug Transporter Activity, Localization and Expression
Abdullah Mayati et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Impaired N-linked glycosylation of uptake and efflux transporters in human non-alcoholic fatty liver disease
John D. Clarke et al.
LIVER INTERNATIONAL (2017)
Clinically Relevant Multidrug Transporters Are Regulated by microRNAs along the Human Intestine
Henrike Bruckmueller et al.
MOLECULAR PHARMACEUTICS (2017)
Preincubation-dependent and long-lasting inhibition of organic anion transporting polypeptide (OATP) and its impact on drug-drug interactions
Yoshihisa Shitara et al.
PHARMACOLOGY & THERAPEUTICS (2017)
Involvement of Nuclear Factor κB, not Pregnane X Receptor, in Inflammation-Mediated Regulation of Hepatic Transporters
Walaa A. Abualsunun et al.
DRUG METABOLISM AND DISPOSITION (2017)
Alternative Splicing: Expanding Diversity in Major ABC and SLC Drug Transporters
Ji Eun Park et al.
AAPS JOURNAL (2017)
Trafficking and other regulatory mechanisms for organic anion transporting polypeptides and organic anion transporters that modulate cellular drug and xenobiotic influx and that are dysregulated in disease
Michael Murray et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Glycans in the intestinal peptide transporter PEPT1 contribute to function and protect from proteolysis
Tamara Stelzl et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2017)
Histone H3 Lysine 4 Trimethylation, Lysine 27 Trimethylation, and Lysine 27 Acetylation Contribute to the Transcriptional Repression of Solute Carrier Family 47 Member 2 in Renal Cell Carcinoma
Qinqin Yu et al.
DRUG METABOLISM AND DISPOSITION (2017)
N-linked glycans do not affect plasma membrane localization of multidrug resistance protein 4 (MRP4) but selectively alter its prostaglandin E2 transport activity
M. Fahad Miah et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)
Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation
Lucie Hyrsova et al.
DRUG METABOLISM REVIEWS (2016)
Epigenetic activation of the drug transporter OCT2 sensitizes renal cell carcinoma to oxaliplatin
Yanqing Liu et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
A phosphotyrosine switch regulates organic cation transporters
Jason A. Sprowl et al.
NATURE COMMUNICATIONS (2016)
Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model
Lisa M. Almond et al.
DRUG METABOLISM AND DISPOSITION (2016)
Protein kinase C affects the internalization and recycling of organic anion transporting polypeptide 1B1
Mei Hong et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders
Hisham Qosa et al.
BRAIN RESEARCH (2015)
Exploiting a novel miR-519c-HuR-ABCG2 regulatory pathway to overcome chemoresistance in colorectal cancer
Kenneth K. W. To et al.
EXPERIMENTAL CELL RESEARCH (2015)
Regulation of the expression of renal drug transporters in KEAP1-knockdown human tubular cells
Hyuk-Sang Jeong et al.
TOXICOLOGY IN VITRO (2015)
What do drug transporters really do?
Sanjay K. Nigam
NATURE REVIEWS DRUG DISCOVERY (2015)
Nuclear Receptors, RXR, and the Big Bang
Ronald M. Evans et al.
CELL (2014)
Signaling Pathways that Regulate Basal ABC Transporter Activity at the Blood-Brain Barrier
David S. Miller et al.
CURRENT PHARMACEUTICAL DESIGN (2014)
MicroRNAs as regulators of drug transporters, drug-metabolizing enzymes, and tight junctions: Implication for intestinal barrier function
Kenji Ikemura et al.
PHARMACOLOGY & THERAPEUTICS (2014)
Renal Circadian Clock Regulates the Dosing-Time Dependency of Cisplatin-Induced Nephrotoxicity in Mice
Masayuki Oda et al.
MOLECULAR PHARMACOLOGY (2014)
Differential Roles of Ubiquitination in the Degradation Mechanism of Cell Surface-Resident Bile Salt Export Pump and Multidrug Resistance-Associated Protein 2
Kensuke Aida et al.
MOLECULAR PHARMACOLOGY (2014)
FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitinproteasome pathway in cancer cells
Kazuhiro Katayama et al.
CANCER SCIENCE (2013)
MiR-223 modulates multidrug resistance via downregulation of ABCB1 in hepatocellular carcinoma cells
Tao Yang et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2013)
Species differences in drug transporters and implications for translating preclinical findings to humans
Xiaoyan Chu et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2013)
Posttranslational Modifications of GLUT4 Affect Its Subcellular Localization and Translocation
Jessica B. A. Sadler et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Application of Permeability-Limited Physiologically-Based Pharmacokinetic Models: Part II - Prediction of P-Glycoprotein Mediated Drug-Drug Interactions with Digoxin
Sibylle Neuhoff et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2013)
A Cancer-Specific Variant of the SLCO1B3 Gene Encodes a Novel Human Organic Anion Transporting Polypeptide 1B3 (OATP1B3) Localized Mainly in the Cytoplasm of Colon and Pancreatic Cancer Cells
Nilay Thakkar et al.
MOLECULAR PHARMACEUTICS (2013)
Modeling of Rifampicin-Induced CYP3A4 Activation Dynamics for the Prediction of Clinical Drug-Drug Interactions from In Vitro Data
Fumiyoshi Yamashita et al.
PLOS ONE (2013)
DNA Methylation and Histone Modification Profiles of Mouse Organic Anion Transporting Polypeptides
Satoki Imai et al.
DRUG METABOLISM AND DISPOSITION (2013)
Hepatocyte Nuclear Factor 1 Regulates the Expression of the Organic Cation Transporter 1 via Binding to an Evolutionary Conserved Region in Intron 1 of the OCT1 Gene
Valerie P. O'Brien et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2013)
Regulation of MicroRNA Expression by Rifampin in Human Hepatocytes
Anuradha Ramamoorthy et al.
DRUG METABOLISM AND DISPOSITION (2013)
Transport Function and Transcriptional Regulation of a Liver-Enriched Human Organic Anion Transporting Polypeptide 2B1 Transcriptional Start Site Variant
Michael J. Knauer et al.
MOLECULAR PHARMACOLOGY (2013)
Impact of Efavirenz on Intestinal Metabolism and Transport: Insights From an Interaction Study With Ezetimibe in Healthy Volunteers
S. Oswald et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)
ABC drug transporter and nuclear receptor expression in human cytotrophoblasts: Influence of spontaneous syncytialization and induction by glucocorticoids
S. Manceau et al.
PLACENTA (2012)
N-glycosylation Dictates Proper Processing of Organic Anion Transporting Polypeptide 1B1
Juan Yao et al.
PLOS ONE (2012)
Interactions of Tyrosine Kinase Inhibitors with Organic Cation Transporters and Multidrug and Toxic Compound Extrusion Proteins
Tsuyoshi Minematsu et al.
MOLECULAR CANCER THERAPEUTICS (2011)
DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma
Elke Schaeffeler et al.
GENOME MEDICINE (2011)
Up-regulation of connexin 32 gene by 5-aza-2′-deoxycytidine enhances vinblastine-induced cytotoxicity in human renal carcinoma cells via the activation of JNK signalling
Y. Takano et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Liver X Receptor α and Farnesoid X Receptor Are Major Transcriptional Regulators of OATP1B1
Henriette E. Meyer Zu Schwabedissen et al.
HEPATOLOGY (2010)
Rapid Modulation of the Organic Anion Transporting Polypeptide 2B1 (OATP2B1, SLCO2B1) Function by Protein Kinase C-mediated Internalization
Kathleen Koeck et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Membrane transporters in drug development
Kathleen M. Giacomini et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
DNA Methylation Profiles of Organic Anion Transporting Polypeptide 1B3 in Cancer Cell Lines
Sayaka Ichihara et al.
PHARMACEUTICAL RESEARCH (2010)
Pathophysiological regulation of renal SLC22A organic ion transporters in acute kidney injury: Pharmacological and toxicological implications
Hideyuki Saito
PHARMACOLOGY & THERAPEUTICS (2010)
Posttranslational regulation of Abcc2 expression by SUMOylation system
Satoko Minami et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
Missense Mutations and Single Nucleotide Polymorphisms in ABCB11 Impair Bile Salt Export Pump Processing and Function or Disrupt Pre-Messenger RNA Splicing
Jane A. Byrne et al.
HEPATOLOGY (2009)
Localization of the human breast cancer resistance protein (BCRP/ABCG2) in lipid rafts/caveolae and modulation of its activity by cholesterol in vitro
Caroline Henrike Storch et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Independent regulation of apical and basolateral drug transporter expression and function in placental trophoblasts by cytokines, steroids, and growth factors
Denis A. Evseenko et al.
DRUG METABOLISM AND DISPOSITION (2007)
The apical conjugate efflux pump ABCC2 (MRP2)
Anne T. Nies et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2007)
Role of human hepatocyte nuclear factor 4 alpha in the expression of drug-metabolizing enzymes and transporters in human Hepatocytes assessed by use of small interfering RNA
Yoshiteru Kamiyama et al.
DRUG METABOLISM AND PHARMACOKINETICS (2007)
New insights into renal transport of urate
Naohiko Anzai et al.
CURRENT OPINION IN RHEUMATOLOGY (2007)
Differential regulation of sinusoidal and canalicular hepatic drug transporter expression by xenobiotics activating drug-sensing receptors in primary human hepatocytes
Emilie Jigorel et al.
DRUG METABOLISM AND DISPOSITION (2006)
Transporters on demand: Intracellular reservoirs and cycling of bile canalicular ABC transporters
Yoshiyuki Wakabayashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Functional analysis of the extracellular cysteine residues in the human organic anion transporting polypeptide, OATP2B1
Emanuel Haenggi et al.
MOLECULAR PHARMACOLOGY (2006)
Functional influence of N-glycosylation in OCT2-mediated tetraethylammonium transport
RM Pelis et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)
Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of ABCG2 (BCRP)
HEMZ Schwabedissen et al.
DRUG METABOLISM AND DISPOSITION (2006)
Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans
S Oswald et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2006)
Absence of N-linked glycosylation does not affect plasma membrane localization of breast cancer resistance protein (BCRP/ABCG2)
K Mohrmann et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2005)
Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists
B Ebert et al.
CARCINOGENESIS (2005)
Regulation of human organic cation transporter hOCT2 by PKA, PI3K, and calmodulin-dependent kinases
I Çetinkaya et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2003)
Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1α
D Jung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The effect of rifampin treatment on intestinal expression of human MRP transporters
MF Fromm et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: A new type of drug/drug interaction
K Westphal et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2000)