Journal
CHINESE CHEMICAL LETTERS
Volume 34, Issue 1, Pages -Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cclet.2022.04.065
Keywords
Visible light; Photocatalysis; Purine derivatives; C-N bond formation; Additive free
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This study developed a method for the photocatalyzed synthesis of 9-arylpurines using non-activated arenes and 9H-purines. The process is highly atom economical and does not require the use of metal or external oxidant.
The photocatalyzed synthesis of 9-arylpurines has been developed using 9H-purines and non-activated arenes. This method is highly atom economical using an acridinium photocatalyst induced by visible light under air atmosphere at room temperature. It employs no metal or external oxidant for the synthesis of 9-arylpurine derivatives.(c) 2022 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.
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