Preparation of amorphous MOF based biomimetic nanozyme with high laccase- and catecholase-like activity for the degradation and detection of phenolic compounds

In spite of the rapid development of nanozyme, it is still challenging to develop multifunctional nanozyme with high oxidase-like activity. In this work, a novel type of amorphous MOF based nanozyme (CA-Cu) with both laccase-and catecholase-like activity was prepared by the facile solvothermal reaction of cyanuric acid and Cu2+ to mimick the N-Cu coordinated environment between the imidazole and Cu2+ in their active site. Due to the excellent activity, substrate universality, recyclability and stability of CA-Cu nanozyme, it shows broad appli-cation prospects in degradation and detection of phenolic compounds. Besides, the structure-activity relation-ship between N-Cu coordinated environment and laccase/catecholase-like activity has been further proved.

Automated summary

In this study, a novel amorphous MOF-based nanozyme CA-Cu with both laccase and catecholase-like activity was prepared, successfully mimicking the N-Cu coordinated environment. CA-Cu nanozyme showed excellent performance in degradation and detection of phenolic compounds, making it highly promising for various applications.