Journal
CELL HOST & MICROBE
Volume 30, Issue 5, Pages 607-611Publisher
CELL PRESS
DOI: 10.1016/j.chom.2022.02.014
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Funding
- National Institute of Allergy and Infectious Diseases of the National Institutes of Health under the Intramural Research Program
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This article discusses the importance of maternal-child microbial seeding interventions for C-section delivered infants and the potential impact on immune development and inflammatory conditions.
Maternal-child microbial seeding interventions expose Cesarean-section (C-section)-delivered infants to the maternal microbiome they bypass during Cesarean delivery. It is theorized such interventions restore the microbiome and normalize immune development to reduce the occurrence of C-section-associated inflammatory conditions. Here we discuss the rationale, evidence, and controversies surrounding such interventions.
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