Journal
CARBOHYDRATE RESEARCH
Volume 514, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2022.108546
Keywords
N -Boc-protected amino acids esters; Peptide mimetic; Glycopeptide derivatives; Theoretical investigation
Funding
- Alexander von Humboldt-Fellowship
Ask authors/readers for more resources
This study presents new and simple synthetic routes for the preparation of novel glycopeptide antibiotics. The structures of the synthesized compounds are elucidated through IR, two-dimensional NMR spectroscopy, and mass spectrometry. The stability of the new glycopeptide derivatives is confirmed through various assessments, and DFT calculations are used to investigate the target precursors.
New, simple, synthetic routes for the preparation of novel glycopeptide antibiotics are described. The structures of the synthesized compounds are elucidated by IR, two-dimensional NMR spectroscopy, and mass spectrometry. The stability of the new glycopeptide derivatives 10a,b is confirmed by assessing the physical character, HOMOLUMO gap energy, ESP, and the corresponding correlation of 2D-NMR analysis. Furtherly, the target precursors are investigated via the DFT/B3LYP/6-311(G) basis set.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available