Related references
Note: Only part of the references are listed.
Article
Cardiac & Cardiovascular Systems
Thais Coutinho et al.
CANADIAN JOURNAL OF CARDIOLOGY
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Review
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Megan E. Hansen et al.
Summary: Differentiating systemic vasculitis from other forms of vasculopathy can be challenging. This review article emphasizes the importance of clinical, radiographic, and histologic clues in distinguishing systemic vasculitis from mimics. Recognition of cardiac manifestations is crucial due to associated mortality. Clinical phenotype, radiographic features, laboratory tests, and histology can help differentiate vasculitis from noninflammatory vasculopathies and guide treatment. Imaging modalities can aid in diagnosis and follow-up, and treatment should be coordinated with an experienced rheumatologist.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
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Vinai C. Bhagirath et al.
Summary: Peripheral artery disease (PAD) is associated with high risks of cardiovascular and limb events and death. Preventive therapies, such as antithrombotic therapy, lipid lowering, blood pressure control, diabetes management, smoking cessation, and exercise programs, have been shown to improve symptoms and reduce complications. However, these therapies are underutilised in PAD patients due to barriers including lack of knowledge and access to secondary prevention programs.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Jennifer A. Rymer et al.
Summary: There are significant gaps in clinical evidence in the management and treatment of peripheral artery disease (PAD) due to ongoing challenges in implementing and designing clinical trials within this field, including fragmented care, coexistence of other cardiovascular diseases, difficulties in recruiting patients, lack of diversity, limited research focus, and insufficient validation evidence.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Noel C. Chan et al.
Summary: Peripheral artery disease is a manifestation of atherosclerosis, and patients have a high risk of vascular complications. Inflammation plays a significant role in the development of atherosclerosis, and anti-inflammatory agents can be used as an additional approach to reduce complications.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
David Nash et al.
Summary: This narrative review explores the relationship between peripheral artery disease and socioeconomic status. It suggests that individuals of low socioeconomic status are more susceptible to developing the disease and face challenges in disease management, leading to adverse outcomes.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Graham R. McClure et al.
Summary: Patients with peripheral artery disease (PAD) have a significant thrombotic risk, but often go unrecognized. Recent Canadian guidelines recommend dual pathway therapy initiation for stable PAD and postrevascularisation patients. However, there is ongoing discussion about identifying those PAD patients who would benefit most from these therapies while minimizing bleeding harm. Clinical equipoise also persists around questions such as the use of dual antiplatelet therapy in conjunction with rivaroxaban after high-risk endovascular interventions and the optimal therapy for patients experiencing acute limb ischemia. Dual pathway therapy with low-dose rivaroxaban and aspirin has emerged as the only regimen to reduce major adverse cardiovascular and limb events for patients with chronic PAD and high-risk comorbidities or limb features, or for patients after revascularisation. Urgently needed are randomized investigations to guide decision making for intensified antithrombotic therapy for patients at high risk.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Darryl Wan et al.
Summary: This review aims to systematically collate literature on the relationship between dietary intake and the presence and progression of peripheral artery disease (PAD). The current evidence is insufficient to establish a clear association between diet and PAD, but the Mediterranean diet may have a protective effect against PAD development.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Matthew J. Eagleton
Summary: There have been significant advancements in endovascular technology, with less invasive procedures being used for complex diseases while still relying on standard 2-dimensional fluoroscopy imaging. Improvements in imaging tools, such as flat-panel detectors and cone-beam computed tomography, have occurred to enhance the visualization of endovascular procedures. Fusion imaging, which overlays preoperative 3-dimensional computed tomographic images, is being used along with artificial intelligence and machine learning to independently adapt to changes during the procedures.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Beth L. Abramson et al.
Summary: This article summarizes the evidence and provides recommendations for the diagnosis, risk stratification, medical and intervention treatments for patients with peripheral artery disease (PAD). Strong recommendations based on high-quality evidence include smoking cessation interventions, structured exercise programs, lipid modifying therapy, antithrombotic therapy, treatment of hypertension, and sodium glucose cotransporter 2 inhibitors for diabetes.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Amanda Morrison et al.
Summary: Atherosclerotic peripheral artery disease (PAD) has different prevalence and clinical presentations between men and women. Women with PAD are more likely to experience functional limitations and clinical deterioration, and they receive less medical therapy. Inflammation and lipid profiles are associated with the development of PAD, and there are sex differences in these factors.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Louisa Shovel et al.
Summary: The global demand for major surgery is increasing, especially in an aging population, and there is a need for clinically applicable approaches to reduce perioperative risks. Prehabilitation has the potential to improve postoperative outcomes by optimizing aerobic capacity and addressing modifiable risk factors before surgery. However, there is a lack of high-quality research specifically focused on prehabilitation for patients awaiting vascular surgery, making it difficult to draw definitive conclusions. Further research is needed to establish the impact of prehabilitation on outcomes for vascular patients.
CANADIAN JOURNAL OF CARDIOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Gregory A. Roth et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2020)
