Association between serum lithium level and incidence of COVID-19 infection

Article Public, Environmental & Occupational Health

Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial

Gilmar Reis et al.

Summary: Treatment with fluvoxamine (100 mg twice daily for 10 days) among high-risk outpatients with early diagnosed COVID-19 reduced the need for hospitalisation defined as retention in a COVID-19 emergency setting or transfer to a tertiary hospital. The trial showed a higher probability of superiority (99.8%) surpassing the prespecified threshold of 97.6%.

LANCET GLOBAL HEALTH (2022)

Add to Collection

Article Psychiatry

Respiratory infections during lithium and valproate medication: a within-individual prospective study of 50,000 patients with bipolar disorder

Mikael Landen et al.

Summary: In a study of 51,509 individuals with bipolar disorder in the Swedish Patient Register, it was found that lithium treatment was associated with a decreased risk of respiratory infections, while valproate treatment was associated with an increased risk.

INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS (2021)

Add to Collection

Letter Psychiatry

Association Between Antipsychotic Use and COVID-19 Mortality Among People With Serious Mental Illness

Katlyn Nemani et al.

JAMA PSYCHIATRY (2021)

Add to Collection

Article Psychiatry

Analysis of the impact of antidepressants and other medications on COVID-19 infection risk in a chronic psychiatric in-patient cohort

Catherine L. Clelland et al.

Summary: This study aimed to investigate the impact of antidepressant use on the risk of COVID-19 infection among long-stay psychiatric in-patients. The results showed a significant protective association between antidepressant use, especially SSRIs, serotonin-norepinephrine reuptake inhibitors, and serotonin-2 antagonist reuptake inhibitors, and COVID-19 infection.

BJPSYCH OPEN (2021)

Add to Collection

Review Psychiatry

Mental disorders and risk of COVID-19-related mortality, hospitalisation, and intensive care unit admission: a systematic review and meta-analysis

Benedetta Vai et al.

Summary: This systematic review and meta-analysis found that pre-existing mental disorders, specifically psychotic and mood disorders, and exposure to antipsychotics and anxiolytics were associated with an increased risk of COVID-19 mortality. The study highlighted the need for targeted approaches to manage and prevent COVID-19 in at-risk patient groups identified in this study. Further research is needed to determine the underlying mechanisms of these associations.

LANCET PSYCHIATRY (2021)

Add to Collection

Article Psychiatry

6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records

Maxime Taquet et al.

Summary: Our study provides evidence of significant neurological and psychiatric morbidity in the 6 months following COVID-19 infection. The risks were highest in patients with severe COVID-19. This information could assist in service planning and research priority identification.

LANCET PSYCHIATRY (2021)

Add to Collection

Article Psychiatry

Bidirectional associations between COVID-19 and psychiatric disorder: retrospective cohort studies of 62 354 COVID-19 cases in the USA

Maxime Taquet et al.

Summary: This study found that survivors of COVID-19 appear to be at increased risk of psychiatric sequelae, and a psychiatric diagnosis might be an independent risk factor for COVID-19. These findings have implications for clinical services, and prospective cohort studies are warranted to further validate the results.

LANCET PSYCHIATRY (2021)

Add to Collection

Review Psychiatry