4.6 Editorial Material

Identification of specific genes involved in schizophrenia aetiology - what difference does it make?

Journal

BRITISH JOURNAL OF PSYCHIATRY
Volume 221, Issue 2, Pages 437-439

Publisher

CAMBRIDGE UNIV PRESS
DOI: 10.1192/bjp.2021.153

Keywords

Schizophrenia; genes; exome; NMDA receptor; SETD1A

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Rare and damaging gene variants that increase the risk of developing schizophrenia have been identified, providing insights into the etiology of the disorder and potentially leading to better treatments.
Genes in which rare, damaging variants substantially increase risk of developing schizophrenia have now been identified. These findings can influence how we think about mental illness in general as well as yielding specific insights into schizophrenia aetiology. Better understanding of underlying biology might eventually lead to improved treatments.

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